Results 41 to 50 of about 12,836,766 (354)

Cell aging and kidney repair [PDF]

open access: yesCell Cycle, 2015
Acute kidney injury (AKI), a rapid loss of renal function, is a major clinical problem associated with a high degree of morbidity and mortality. During AKI, a stressor, such as ischemia-reperfusion (IR), causes tubular cell death, interstitial inflammation and vascular damage.
Nathan, Susnik   +2 more
openaire   +2 more sources

Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures [PDF]

open access: yes, 2013
The repair of articular cartilage is challenging due to the sparse native cell population combined with the avascular and aneural nature of the tissue. In recent years cartilage tissue engineering has shown great promise.
Blitterswijk, C.A. van   +4 more
core   +3 more sources

Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves

open access: yesGlia, 2019
Schwann cells respond to nerve injury by cellular reprogramming that generates cells specialized for promoting regeneration and repair. These repair cells clear redundant myelin, attract macrophages, support survival of damaged neurons, encourage axonal ...
K. Jessen, P. Arthur-Farraj
semanticscholar   +1 more source

Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner

open access: yesCell, 2020
Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet whether these cells contribute to cognitive deficits and secondary inflammatory pathology remains poorly understood.
Emily F. Willis   +12 more
semanticscholar   +1 more source

Cell therapy for cardiac repair [PDF]

open access: yesBritish Medical Bulletin, 2010
Heart failure is a leading cause of morbidity and mortality worldwide. The current strategies for treatment are limited and new therapeutic approaches are needed. This review describes research performed in animal models of cardiac disease and clinical trials and discusses the mechanisms involved in possible beneficial effects of cell therapy.
Joon, Lee, Cesare M, Terracciano
openaire   +2 more sources

Transplantation of GABAergic Cells Derived from Bioreactor-Expanded Human Neural Precursor Cells Restores Motor and Cognitive Behavioral Deficits in a Rodent Model of Huntington's Disease

open access: yesCell Transplantation, 2013
Huntington's disease (HD) is a neurodegenerative disorder that is characterized by progressive dementia, choreiform involuntary movements, and emotional deterioration.
Marcus C. McLeod   +7 more
doaj   +1 more source

BDNF Induced Translation of Limk1 in Developing Neurons Regulates Dendrite Growth by Fine-Tuning Cofilin1 Activity

open access: yesFrontiers in Molecular Neuroscience, 2019
Dendritic growth and branching are highly regulated processes and are essential for establishing proper neuronal connectivity. There is a critical phase of early dendrite development when these are heavily regulated by external cues such as trophic ...
Sreenath Ravindran   +3 more
doaj   +1 more source

Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis [PDF]

open access: yes, 2012
Copyright @ 2012 Nature Publishing GroupThis article has been made available through the Brunel Open Access Publishing Fund.Background: The objective of this study was to determine the molecular mechanism(s) responsible for cellular radiosensitivity in ...
A Musio   +30 more
core   +1 more source

Stem Cell Differentiation: Cardiac Repair [PDF]

open access: yesCells Tissues Organs, 2007
Cellular transplantation has been employed for several years to deliver donor cardiomyocytes to normal and injured hearts. Recent reports of a variety of stem cells with apparent cardiomyogenic potential have raised the possibility of cell transplantation-based therapeutic interventions for heart disease.
Michael, Rubart, Loren J, Field
openaire   +2 more sources

Regulatory Effects of Damaged Renal Epithelial Cells After Repair by Porphyra yezoensis Polysaccharides with Different Sulfation Degree on the Calcium Oxalate Crystal–Cell Interaction

open access: yesInternational Journal of Nanomedicine, 2021
Xin-Yuan Sun,1,* Hui Zhang,2,* Ji-Wang Deng,1,* Bang-Xian Yu,1 Yi-Han Zhang,1 Jian-Ming Ouyang2 1Department of Urology, Guangzhou Institute of Urology, Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical ...
Sun XY   +5 more
doaj  

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