Results 71 to 80 of about 12,836,766 (354)
DNA Repair in Mammalian Cells [PDF]
Cellular and Molecular Life Sciences, 2009 Complementary base pairing underlies the genetic template function of the DNA double helix. Therefore, to assure faithful DNA transactions, cells must adhere to a strict application of the Watson-Crick base pairing principle.Yet, mispairing does arise in DNA, most frequently as a result of DNA polymerase errors or base damage.
Kunz, C., Saito, Y., Schär, P.
openaire +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Procesos puntuales, densidades producto y biología celular
Revista Colombiana de Estadística, 2005 En este artículo se explica cómo los procesos puntuales han sido usados con éxito para modelar problemas de poblaciones celulares. En particular, se muestra la utilidad de la técnica de densidades producto para tratar un problema de células sujetas a ...
VISWANATHAN ARUNACHALAM
doaj +2 more sources
European Journal of Medical ResearchObjective Red blood cell distribution width (RDW) is a marker of inflammation and oxidative stress, and its elevation has been associated with poor outcomes in critically ill patients.
Qing Cao +4 more
doaj +1 more source
MethodsX, 2020 Three-dimensional (3D) cell culturing has several advantages over 2D cultures. 3D cell cultures more accurately mimic the in vivo environment, which is vital to obtain reliable results in disease modelling and toxicity testing.
Jeffrey Aalders +4 more
doaj +1 more source
Enhanced Tissue Integration During Cartilage RepairIn VitroCan Be Achieved by Inhibiting Chondrocyte Death at the Wound Edge [PDF]
, 2009 Objective: Experimental wounding of articular cartilage results in cell death at the lesion edge. The objective of this study was to investigate whether inhibition of this cell death results in enhanced integrative cartilage repair.
Archer, Charles W. +7 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Revista Colombiana de Estadística, 2005 In this paper an attempt is made to explain how point processes have been successfully used in modeling cell biology problems. In particular we demonstrate the utility of the product density techniques in dealing with cells subject to radiation.
Arunachalam Viswanathan
doaj
Hydrogen peroxide induced genomic instability in nucleotide excision repair-deficient lymphoblastoid cells [PDF]
, 2010 Copyright @ 2010 Gopalakrishnan et al; licensee BioMed Central Ltd.Background The Nucleotide Excision Repair (NER) pathway specialises in UV-induced DNA damage repair. Inherited defects in the NER can predispose individuals to Xeroderma Pigmentosum (XP).
Gopalakrishnan, K +5 more
core +2 more sources
Experientia, 2020 is becoming a promising target in cancer therapy and a powerful prognostic and predictive factor in several cancer types. Thus, speci fi c APE1 inhibitors have been developed targeting: i) the endonuclease activity; ii) the redox function and iii) the ...
Marta Codrich +9 more
semanticscholar +1 more source