Results 71 to 80 of about 1,443,234 (190)

Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis. [PDF]

, 2018
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Akif A. Khawaja, Catherine W. M. Ong, Catherine W. M. Ong, Deborah L. W. Chong, Joanna C. Porter, Jon S. Friedland, Naomi J. Guppy, Sara Brilha, Sara Brilha   +8 more
core   +6 more sources

One special question to start with: can HIF/NFkB be a target in inflammation? [PDF]

, 2015
Hypoxia and Inflammation are strictly interconnected with important consequences at clinical and therapeutic level. While cell and tissue damage due to acute hypoxia mostly leads to cell necrosis, in chronic hypoxia, cells that are located closer to ...
CARNEVALE, ILARIA, DE SANTIS, Elena, Limana, F, Perrone, Ga, POLLETTA, LUCIA, RUNCI, ALESSANDRA, RUSSO, Matteo Antonio, SANSONE, LUIGI, TAFANI, MARCO   +8 more
core   +1 more source

Cardiac repair by stem cells

Cell Death & Differentiation, 2007
Peer ...
Sánchez, Ana, García-Sancho, Javier
openaire   +3 more sources

TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair. [PDF]

, 2016
E-cadherin is a cell adhesion molecule best known for its function in suppressing tumor progression and metastasis. Here we show that E-cadherin promotes nucleotide excision repair through positively regulating the expression of xeroderma pigmentosum ...
Barcellos-Hoff, MH, He, YY, Qiang, L, Shah, P   +3 more
core   +1 more source

A novel TGFβ1–Hs3st2–tau axis regulates tau pathology and synaptic integrity

Frontiers in Neuroscience
IntroductionTauopathies are a group of neurodegenerative diseases characterized by the pathological accumulation of tau protein. The hippocampus, a brain region crucial for learning and memory, is particularly susceptible to tau-induced damage.
Rafael Castillo-Negrete, Rafael Castillo-Negrete, Rafael Castillo-Negrete, Heloise Merrick, Sethupathiraj Selvaraj, Minh Bao Huynh, Xavier Laffray, Ajitha Thuraisamy, Martin Diener, Peter Jedlicka, Peter Jedlicka, Peter Jedlicka, Mohand Ouidir Ouidja, Dulce Papy-Garcia   +13 more
doaj   +1 more source

Comparison of Olfactory Bulbar and Mucosal Cultures in a Rat Rhizotomy Model

Cell Transplantation, 2014
In an ongoing clinical trial, a spinal injured patient who received a transplant of autologous cells cultured from the olfactory bulb is showing greater functional benefit than three previous patients with transplants of mucosal origin.
Ahmed Ibrahim, Daqing Li, Andrew Collins, Pawel Tabakow, Geoffrey Raisman FRS, Ying Li   +5 more
doaj   +1 more source

The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity [PDF]

, 2015
Different tissues contain diverse and dynamic cellular niches, providing distinct signals to tissue-resident or migratory infiltrating immune cells.
Agathocleous, Alcedo, Aza-Blanc, Bai, Bellavia, Boyman, Brennan, Buckland, Chan, Cheng, Crompton, D'Acquisto, de la Roche, Decker, Dennler, Drakopoulou, El Andaloussi, Feske, Finetti, Furler, Furmanski, Furmanski, Gilmour, Hafezi-Moghadam, Hager-Theodorides, Hager-Theodorides, Hatayama, Huang, Hui, Huse, Ingham, Jiang, Kahn, Kasper, Kim, Kumabe, Lau, Le, Lee, Li, Lowrey, Marigo, Matise, Medyouf, Michel, Mo, Neumann, Nielsen, Outram, Park, Perry, Pola, Priatel, Priatel, Reynolds, Riobó, Rohatgi, Rowbotham, Rowbotham, Rowbotham, Sacedón, Sacedón, Sato, Seo, Shah, Shimizu, Smith, Smith-Garvin, Stewart, Thompson, Varjosalo, Wakelin, Yamane   +72 more
core   +5 more sources

Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury

eLife, 2020
Previously we showed that YAP/TAZ promote not only proliferation but also differentiation of immature Schwann cells (SCs), thereby forming and maintaining the myelin sheath around peripheral axons (Grove et al., 2017).
Matthew Grove, Hyunkyoung Lee, Huaqing Zhao, Young-Jin Son   +3 more
doaj   +1 more source

“Self-repairing” nanoshell for cell protection

Chemical Science, 2015
Self-repairing biohybrid nanoshells provide living cells with high activity and extended viability in harsh micro-environments.
Jiang, Nan, Yang, Xiao Yu, Ying, Guo Liang, Shen, Ling, Liu, Jing, Geng, Wei, Dai, Ling Jun, Liu, Shao Yin, Cao, Jian, Tian, Ge, Sun, Tao Lei, Li, Shi Pu, Su, Bao Lian   +12 more
openaire   +4 more sources

Machines on Genes: Enzymes that Make, Break and Move DNA and RNA [PDF]

, 2010
As the vital information repositories of the cell, the nucleic acids DNA and RNA pose many challenges as enzyme substrates. To produce, maintain and repair DNA and RNA, and to extract the genetic information that they encode, a battery of remarkable ...
Bates, Belousoff, Ben F. Luisi, Lilley, Marshall, Olorunniji, Rice, Richard P. Bowater, Sherratt, Smith, Szczelkun, Tomlinson, W. Marshall Stark, Weinzierl   +13 more
core   +1 more source