Results 111 to 120 of about 5,248,930 (285)

Control of Bacillus subtilis Replication Initiation during Physiological Transitions and Perturbations

open access: yesmBio, 2019
Bacillus subtilis and Escherichia coli are evolutionarily divergent model organisms whose analysis has enabled elucidation of fundamental differences between Gram-positive and Gram-negative bacteria, respectively.
John T. Sauls   +5 more
doaj   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Accuracy and Reliability of Oral Exfoliative Cytology in Age Estimation: An Observational Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Aim and Objectives: Age and gender identification are critical in forensic investigations, especially for unidentified human bodies. This study explores differences in nuclear size, nuclear area, and nuclear-cytoplasmic ratio between healthy individuals ...
Naseemoon Shaik   +6 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Genome-Wide Screen for Haploinsufficient Cell Size Genes in the Opportunistic Yeast Candida albicans

open access: yesG3: Genes, Genomes, Genetics, 2017
One of the most critical but still poorly understood aspects of eukaryotic cell proliferation is the basis for commitment to cell division in late G1 phase, called Start in yeast and the Restriction Point in metazoans.
Julien Chaillot   +3 more
doaj   +1 more source

Effect of Dedifferentiation on Time to Mutation Acquisition in Stem Cell-Driven Cancers

open access: yes, 2013
Accumulating evidence suggests that many tumors have a hierarchical organization, with the bulk of the tumor composed of relatively differentiated short-lived progenitor cells that are maintained by a small population of undifferentiated long-lived ...
Gutenkunst, Ryan N., Jilkine, Alexandra
core   +3 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Does Cell Size Impact Chloroplast Genome Size?

open access: yesFrontiers in Plant Science, 2017
There is a strong positive relationship between nuclear genome size and cell size across the eukaryotic domain, but the cause and effect of this relationship is unclear.
David R. Smith
doaj   +1 more source

Quantification of Cell Subpopulations, Fractions of Dead Cells and Debris in Cell Suspensions by Laser Diffractometry [PDF]

open access: yes, 1992
Laser diffractometry was employed for size analysis in liver cell and blood cell suspensions to assess its suitability for characterizing cell populations.
Blunk, Torsten, Müller, R. H., Rudt, S.
core  

Effect of particle polydispersity on the irreversible adsorption of fine particles on patterned substrates

open access: yes, 2012
We performed extensive Monte Carlo simulations of the irreversible adsorption of polydispersed disks inside the cells of a patterned substrate. The model captures relevant features of the irreversible adsorption of spherical colloidal particles on ...
A. B. Lima   +4 more
core   +1 more source

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