Results 51 to 60 of about 2,922,174 (317)

Simulated Micro-, Lunar, and Martian Gravities on Earth—Effects on Escherichia coli Growth, Phenotype, and Sensitivity to Antibiotics

open access: yesLife, 2022
Bacterial behavior has been studied under microgravity conditions, but very little is known about it under lunar and Martian gravitational regimes. An Earth-based approach was designed and implemented using inclined clinostats and an in-house-developed ...
Lily A. Allen   +6 more
doaj   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

DNA Content, Cell Size, and Cell Senescence [PDF]

open access: yesTrends in Biochemical Sciences, 2019
A recent study assessed the impact of cell size on various cell properties. Oversized yeast cells display slow cell division, cytoplasmic dilution, and transcriptomic and proteomic alterations. It highlights commonalities between aging yeast and mammalian cells, suggesting the existence of a range of DNA content: cell volume ratio ensuring optimal ...
openaire   +2 more sources

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

Evaluating cell growth and hypoxic regions of 3D spheroids via a machine learning approach

open access: yesMachine Learning: Science and Technology
This study investigated the applicability of the area of spheroids and hypoxic regions for efficient evaluation of drug efficacy using machine learning (ML).
Jaekak Yoo   +9 more
doaj   +1 more source

Adaptive abilities of benthic microalga Attheya ussurensis to prolonged contamination with a salt of hexavalent chromium in culture

open access: yesИзвестия ТИНРО, 2014
Adaptive capacity of benthic microalga Attheya ussurensis (Bacillariophyta) from Peter the Great Bay, Japan Sea to the medium contamination with a salt of hexavalent chromium is tested in laboratory culture.
Nina A. Aizdaicher, Olga B. Gostyukhina
doaj   +1 more source

Dominance of small-sized phytoplankton in a Mediterranean eutrophic coastal lagoon

open access: yesAdvances in Oceanography and Limnology, 2023
The predator-prey relationship is generally size-specific in the pelagic food webs. Phytoplankton cell size structure can provide information on the successive levels of consumers and therefore on the energy that can flow towards the top consumers. This
Silvia Pulina   +6 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

Sizing Up Lung Stem Cells [PDF]

open access: yesDevelopmental Cell, 2014
Mammalian lungs are comprised of conducting airways and alveoli. How the distinct epithelial linings of these two zones are differentially specified and maintained is not fully understood. In this issue of Developmental Cell, two groups find critical roles for the Hippo pathway in regulation of lung progenitor cell differentiation.
openaire   +2 more sources

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