Results 1 to 10 of about 14,964,075 (408)
T Cells Use Rafts for Survival [PDF]
Immunity, 2010 T cell homeostasis must be tightly controlled. In this issue of Immunity, Cho et al. (2010) describe results that begin to define the roles of the T cell receptor, self-peptide-MHC ligands, cytokines, and membrane rafts in this dynamic process.
David M. Kranz, Jennifer D. Stone
openaire +3 more sources
Archivos de Cardiología de México, 2023 Objetivo: Analizar la utilidad y relevancia clínica de la evaluación mediante ecocardiografía basada en las curvas de deformación auricular miocárdica con imágenes vectoriales de velocidad (VVI) de speckle-tracking, en el análisis de las extrasístoles ...
José M. Soler +5 more
doaj +1 more source
Oncogenes in Cell Survival and Cell Death [PDF]
Cold Spring Harbor Perspectives in Biology, 2012 The transforming effects of proto-oncogenes such as MYC that mediate unrestrained cell proliferation are countered by "intrinsic tumor suppressor mechanisms" that most often trigger apoptosis. Therefore, cooperating genetic or epigenetic effects to suppress apoptosis (e.g., overexpression of BCL2) are required to enable the dual transforming processes ...
Jake Shortt +2 more
openaire +2 more sources
Particle and Fibre Toxicology, 2021 Background Today, cosmetic products are very popular with both men and women to improve their appearance and increase their social acceptability. Results In this study, nano-sized (30–300 nm) plastic particles were isolated from the commercial face ...
Ponnusamy Manogaran Gopinath +6 more
doaj +1 more source
Bio-Protocol, 2013 The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela +2 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Lymphocyte homeostasis, activation and differentiation crucially rely on basal autophagy. The fine-tuning of this process depends on autophagy-related (ATG) proteins and their interaction with the trafficking machinery that orchestrates the membrane ...
Francesca Finetti +11 more
doaj +1 more source
Nature, 2004 A jaded observer might consider the cancer research field near maturity and surprising new results improbable. But work on the protein netrin-1 shows that unforeseen insights into cancer can still occur.
Fearon, Eric R., Cho, Kathleen R.
openaire +3 more sources
Cell Reports, 2015 Intestinal epithelial homeostasis requires continuous renewal supported by stem cells located in the base of the crypt. Disruption of this balance results in failure to regenerate and initiates tumorigenesis.
Victoria Llado +11 more
doaj +1 more source
The function of autophagy as a fundamental process of preserving cell homeostasis [PDF]
Biomedicinska istraživanja, 2021 Autophagy is a dynamic process, conserved in all eukaryotes. It is responsible for the degradation of cytoplasmic content. Autophagy is crucial in cell survival and cell death.
Nikolina Elez-Burnjaković +3 more
doaj +1 more source
PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7
Nature Communications, 2016 Rab7 is a critical GTPase for endosome maturation and it is implicated in the endocytic traffic of several receptors, including EGFR. In this study, the authors reveal the potential role of PTEN in the endocytic trafficking pathway of EGFR, which is ...
Swapnil Rohidas Shinde +1 more
doaj +1 more source