Results 1 to 10 of about 3,396,679 (311)

The function of autophagy as a fundamental process of preserving cell homeostasis [PDF]

open access: yesBiomedicinska istraživanja, 2021
Autophagy is a dynamic process, conserved in all eukaryotes. It is responsible for the degradation of cytoplasmic content. Autophagy is crucial in cell survival and cell death.
Nikolina Elez-Burnjaković   +3 more
doaj   +1 more source

PTEN-lipid Binding Assay

open access: yesBio-Protocol, 2013
The lipid and protein interactions are an integral and important part of many cellular signaling pathways. The understanding of the selective and specific interaction of the given lipid molecule with the target protein is required for studying cellular ...
Sridhar Kavela   +2 more
doaj   +1 more source

Evaluación de formas cortas de extrasístoles auriculares recurrentes mediante ecocardiografía con deformación auricular izquierda en pacientes ambulatorios sin cardiopatía orgánica

open access: yesArchivos de Cardiología de México, 2023
Objetivo: Analizar la utilidad y relevancia clínica de la evaluación mediante ecocardiografía basada en las curvas de deformación auricular miocárdica con imágenes vectoriales de velocidad (VVI) de speckle-tracking, en el análisis de las extrasístoles ...
José M. Soler   +5 more
doaj   +1 more source

Prospects on the nano-plastic particles internalization and induction of cellular response in human keratinocytes

open access: yesParticle and Fibre Toxicology, 2021
Background Today, cosmetic products are very popular with both men and women to improve their appearance and increase their social acceptability. Results In this study, nano-sized (30–300 nm) plastic particles were isolated from the commercial face ...
Ponnusamy Manogaran Gopinath   +6 more
doaj   +1 more source

PTEN Regulates Glucose Transporter Recycling by Impairing SNX27 Retromer Assembly

open access: yesCell Reports, 2017
Summary: The tumor suppressor PTEN executes cellular functions predominantly through its phosphatase activity. Here we identified a phosphatase-independent role for PTEN during vesicular trafficking of the glucose transporter GLUT1.
Swapnil Rohidas Shinde   +1 more
doaj   +1 more source

Isolation and Characterization of Crab Haemolymph Exosomes and Its Effects on Breast Cancer Cells (4T1) [PDF]

open access: yesCell Journal, 2021
Objective: The use of animal or plant exosomes in cancer treatment is promising because of their easy access and low cost. Freshwater crabs are used in traditional Iranian medicine to treat cancer.
Leila Rezakhani   +4 more
doaj   +1 more source

PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7

open access: yesNature Communications, 2016
Rab7 is a critical GTPase for endosome maturation and it is implicated in the endocytic traffic of several receptors, including EGFR. In this study, the authors reveal the potential role of PTEN in the endocytic trafficking pathway of EGFR, which is ...
Swapnil Rohidas Shinde   +1 more
doaj   +1 more source

Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ

open access: yesCell Reports, 2015
Intestinal epithelial homeostasis requires continuous renewal supported by stem cells located in the base of the crypt. Disruption of this balance results in failure to regenerate and initiates tumorigenesis.
Victoria Llado   +11 more
doaj   +1 more source

Effects of zinc oxide and calcium–doped zinc oxide nanocrystals on cytotoxicity and reactive oxygen species production in different cell culture models [PDF]

open access: yesRestorative Dentistry & Endodontics, 2020
ObjectivesThis study aimed to synthesize nanocrystals (NCs) of zinc oxide (ZnO) and calcium ion (Ca2+)-doped ZnO with different percentages of calcium oxide (CaO), to evaluate cytotoxicity and to assess the effects of the most promising NCs on ...
Gabriela Leite de Souza   +7 more
doaj   +1 more source

Vesicular Zinc Modulates Cell Proliferation and Survival in the Developing Hippocampus

open access: yesCells, 2023
In the brain, vesicular zinc, which refers to a subset of zinc that is sequestered into synaptic vesicles by zinc transporter 3 (ZnT3), has extensive effects on neuronal signalling and modulation.
Selena Fu   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy