Results 31 to 40 of about 14,964,075 (408)
Signal transduction and activator of transcription-3 (STAT3) in patients with colorectal cancer: associations with the phenotypic features of the tumour and host [PDF]
, 2017 Purpose: In patients with colorectal cancer (CRC), a high-density local inflammatory infiltrate response is associated with improved survival, whereas elevated systemic inflammatory responses are associated with poor survival.
Clark, Jennifer +7 more
core +1 more source
Cell Transplantation, 1995 Tissue storage prior to intracerebral transplantation would represent a major advantage when conducting clinical transplantation trials in that the procurement of the embryonic donor tissue and the timing of neurosurgery could be planned more efficiently.
Eva M. Frodl +3 more
doaj +1 more source
Effect of Overdispersion of Lethal Lesions on Cell Survival Curves [PDF]
Biomed. Phys. Eng. Express 8, 045011 (2022), 2021 We explore the effects of overdispersed DNA lesion distribution on the shapes of cell surviving curves of mammalian cells exposed to hadrons at various doses. To provide a theoretical framework in resolving discrepancies between experimental data and Linear-quadratic (LQ)model predictions, we employ a non-Poisson distribution of lethal lesions together
arxiv
High IKKα expression is associated with reduced time to recurrence and cancer specific survival in oestrogen receptor (ER)-positive breast cancer [PDF]
, 2017 The aim of our study was to examine the relationship between tumour IKKα expression and breast cancer recurrence and survival. Immunohistochemistry was employed in a discovery and a validation tissue microarray to assess the association of tumour IKKα ...
Bennett, Lindsay +7 more
core +2 more sources
Frontiers in Physiology, 2020 Dementia is one among the consequences of aging, and amnesia is often one of the most common symptoms. The lack of memory, as a consequence of both “healthy” aging or neurodegenerative conditions, such as in Alzheimer’s disease, has a dramatic impact on ...
Flavia Messina +4 more
doaj +1 more source
Frontiers in Oncology, 2021 Nuclear Receptor Binding Protein 2 (NRBP2), one of the pseudokinases discovered during a screen of neural differentiation genes, inhibits tumor progression in medulloblastoma and hepatocellular carcinoma.
Zhiyu Li +7 more
doaj +1 more source
Nature Communications, 2017 Tissue architecture contributes to pancreatic ductal adenocarcinoma (PDAC) phenotypes. Cancer cells within PDAC form gland-like structures embedded in a collagen-rich meshwork where nutrients and oxygen are scarce. Altered metabolism is needed for tumour
O. Olivares +19 more
semanticscholar +1 more source
Survival Seq2Seq: A Survival Model based on Sequence to Sequence Architecture [PDF]
arXiv, 2022 This paper introduces a novel non-parametric deep model for estimating time-to-event (survival analysis) in presence of censored data and competing risks. The model is designed based on the sequence-to-sequence (Seq2Seq) architecture, therefore we name it Survival Seq2Seq.
arxiv
Contribution of Anoctamins to Cell Survival and Cell Death [PDF]
Cancers, 2019 Before anoctamins (TMEM16 proteins) were identified as a family of Ca2+-activated chloride channels and phospholipid scramblases, the founding member anoctamin 1 (ANO1, TMEM16A) was known as DOG1, a marker protein for gastrointestinal stromal tumors (GIST). Meanwhile, ANO1 has been examined in more detail, and the role of ANO1 in cell proliferation and
Kunzelmann, Karl +4 more
openaire +4 more sources
Rapamycin induces transactivation of the EGFR and increases cell survival. [PDF]
, 2009 The mammalian target of rapamycin (mTOR) signaling network regulates cell growth, proliferation and cell survival. Deregulated activation of this pathway is a common event in diverse human diseases such as cancers, cardiac hypertrophy, vascular ...
Chaturvedi, D +4 more
core +2 more sources