Results 51 to 60 of about 14,964,075 (408)
AAV-mediated and pharmacological induction of Hsp70 expression stimulates survival of retinal ganglion cells following axonal injury. [PDF]
, 2015 We evaluated the effect of AAV2- and 17-AAG (17-N-allylamino-17-demethoxygeldanamycin)-mediated upregulation of Hsp70 expression on the survival of retinal ganglion cells (RGCs) injured by optic nerve crush (ONC).
Bekerman, V +9 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2022 Humanin (HN) belongs to a member of mitochondrial-derived peptides (MDPs) which are encoded by mitochondrial genes. HN shares sequence homology with thirteen HN-like proteins, named MTRNR2L1 to MTRNR2L13, which encompass 24–28 amino acid residues in ...
Sipin Zhu +4 more
doaj +1 more source
Effect of preheating on the cytotoxicity of bulk-fill composite resins [PDF]
Journal of Dental Research, Dental Clinics, Dental Prospects, 2020 Background. Due to the effect of pre-heating on the degree of conversion of composite resins and the possible effect on cytotoxicity, the effect of pre-heating of bulk-fill composite resins was investigated on cytotoxicity in this study. Methods. In this
Mohammad Esmaeel Ebrahimi Chaharom +8 more
doaj +1 more source
Signalling for B cell survival
Current Opinion in Cell Biology, 2018 The number of mature B cells is carefully controlled by signalling from receptors that support B cell survival. The best studied of these are the B cell antigen receptor (BCR) and BAFFR. Recent work has shown that signalling from these receptors is closely linked, involves the CD19 co-receptor, and leads to activation of canonical and non-canonical NF ...
Edina Schweighoffer +2 more
openaire +5 more sources
Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL [PDF]
, 2015 In chronic lymphocytic leukemia (CLL), Notch1 and Notch2 signaling is constitutively activated and contributes to apoptosis resistance. We show that genetic inhibition of either Notch1 or Notch2, through small-interfering RNA, increases apoptosis of CLL ...
Baldoni, Stefano +9 more
core +2 more sources
Kaohsiung Journal of Medical Sciences, 2021 Cullin 4B (CUL4B) was reported to be closely related to the progression of some tumors, but its function in clear cell renal cell carcinoma (ccRCC) has not been reported.
Hai‐Feng Yang +3 more
doaj +1 more source
Dark-Induced Barley Leaf Senescence – A Crop System for Studying Senescence and Autophagy Mechanisms
Frontiers in Plant Science, 2021 This review synthesizes knowledge on dark-induced barley, attached, leaf senescence (DILS) as a model and discusses the possibility of using this crop system for studying senescence and autophagy mechanisms.
Ewelina Paluch-Lubawa +2 more
doaj +1 more source
In Vitro and in vivo anti-tumoral effects of the flavonoid apigenin in malignant mesothelioma [PDF]
, 2017 Malignant mesothelioma (MM) is a tumor arising from mesothelium. MM patients' survival is poor. The polyphenol 4',5,7,-trihydroxyflavone Apigenin (API) is a "multifunctional drug". Several studies have demonstrated API anti-tumoral effects.
Andrea Modesti +13 more
core +2 more sources
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
Cancers, 2016 The generation and release of membrane-enclosed packets from cancer cells, called extracellular vesicles (EVs), play important roles in propagating transformed phenotypes, including promoting cell survival. EVs mediate their effects by transferring their
B. Kreger +3 more
semanticscholar +1 more source