Results 1 to 10 of about 13,969,136 (421)
New Sesquiterpene Glycosides from the Flowers of Aster koraiensis and Their Inhibition Activities on EGF- and TPA-Induced Cell Transformation. [PDF]
Plants (Basel), 2023 In total, four new eudesmane-type sesquiterpene glycosides, askoseosides A–D (1–4), and 18 known compounds (5–22) were isolated from the flowers of Aster koraiensis via chromatographic techniques.
Seo YH +11 more
europepmc +2 more sources
Frontiers in Plant Science, 2020 Successful regeneration of genetically modified plants from cell culture is highly dependent on the species, genotype, and tissue-type being targeted for transformation. Studies in some plant species have shown that when expression is altered, some genes
Andika Gunadi, Jiankang Liu
exaly +3 more sources
Dendrosomal nanocurcumin prevents EBV-associated cell transformation by targeting the lytic cycle genes of the Epstein-Barr virus in the generation of lymphoblastoid cell line [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Targeting the lytic cycle of the Epstein-Barr virus (EBV) has been considered a new treatment strategy for malignancies caused by this virus.
Mahboobeh Cheragh +3 more
doaj +1 more source
Novel Therapeutic Approaches for KRAS-Mutated Lung Cancer Involving LZTR1 Genetic Alteration
Medical Sciences Forum, 2023 A total of 30% of lung adenocarcinoma are driven by activating KRAS mutations. The treatment options for KRAS-mutant lung cancer are still limited as a challenge for therapy is the high heterogeneity within KRAS mutant tumors.
Raj N. Sewduth +3 more
doaj +1 more source
Diffuse osteolytic lesions in leukemic transformation of myelofibrosis [PDF]
Archive of Oncology, 2007 Myelofibrosis is a clonal myeloproliferative disorder characterized by splenomegaly, abnormal deposition of reticulin and collagen in the bone marrow, extramedullary hematopoiesis, dacryocytosis and leukoerythroblastic blood smear.
Jurišić Vladimir +3 more
doaj +1 more source
Viruses, 2021 It is suggested that HPV-18 variants from the A lineage have higher oncogenic potential compared to B variants. Some studies show uneven distribution of HPV-18 variants in cervical adenocarcinomas and squamous cell carcinomas.
Emily Montosa Nunes +9 more
doaj +1 more source
Expression and cell transformation activity of dynactin‐associated protein isoforms
FEBS Open Bio, 2021 Overexpression of human dynactin‐associated protein isoform a (dynAPa) transforms NIH3T3 cells. DynAPa is a single‐pass transmembrane protein with a carboxy‐terminal region exposed to the outside of cells. According to the NCBI RefSeq database, there may
Xiaobo Yin +12 more
doaj +1 more source
Frontiers in Oncology, 2021 The c-Myc protein (MYC) is a transcription factor with strong oncogenic potential controlling fundamental cellular processes. In most human tumors, MYC is overexpressed by enhanced transcriptional activation, gene amplification, chromosomal ...
Alexander Mödlhammer +4 more
doaj +1 more source
Marine Drugs, 2020 Astaxanthin from H. pluvialis is an antioxidant and presents a promising application in medicine for human health. The two-stage strategy has been widely adopted to produce astaxanthin by the Haematococcus industry and research community.
Feng Li +9 more
doaj +1 more source
Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase
eLife, 2023 The activation of Src kinase in cells is strictly controlled by intramolecular inhibitory interactions mediated by SH3 and SH2 domains. They impose structural constraints on the kinase domain holding it in a catalytically non-permissive state.
Lenka Koudelková +9 more
doaj +1 more source