Results 31 to 40 of about 326,716 (261)

Overview on HTLV-I p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesis.

Frontiers in Microbiology, 2012
The human T-lymphotropic virus type-1 (HTLV-1) is etiologically linked to adult T-cell leukemia/lymphoma (ATLL) and tropical spastic paraparesis/ HTLV-1 associated myelopathy (TSP/HAM).
Christophe eNicot, xue tao ebai
doaj   +1 more source

SPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infection. [PDF]

PLoS Pathogens, 2013
Little is known about immediate phases after viral infection and how an incoming viral genome complex counteracts host cell defenses, before the start of viral gene expression.
Sabrina Schreiner, Sarah Kinkley, Carolin Bürck, Andreas Mund, Peter Wimmer, Tobias Schubert, Peter Groitl, Hans Will, Thomas Dobner   +8 more
doaj   +1 more source

Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]

, 2016
Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core   +1 more source

Herpesviral microRNAs in Cellular Metabolism and Immune Responses

Frontiers in Microbiology, 2017
The microRNAs (miRNAs) function as a key regulator in many biological processes through post-transcriptional suppression of messenger RNAs. Recent advancements have revealed that miRNAs are involved in many biological functions of cells.
Hyoji Kim, Hisashi Iizasa, Yuichi Kanehiro, Sintayehu Fekadu, Hironori Yoshiyama   +4 more
doaj   +1 more source

A dynamic Bayesian nonlinear mixed-effects model of HIV response incorporating medication adherence, drug resistance and covariates

, 2011
HIV dynamic studies have contributed significantly to the understanding of HIV pathogenesis and antiviral treatment strategies for AIDS patients. Establishing the relationship of virologic responses with clinical factors and covariates during long-term ...
Acosta, Edward P., Holden-Wiltse, Jeanne, Huang, Yangxin, Wu, Hulin   +3 more
core   +1 more source

Merkel cell polyomavirus small T antigen is a viral transcription activator that is essential for viral genome maintenance.

PLoS Pathogens, 2022
Merkel cell polyomavirus (MCV) is a small DNA tumor virus that persists in human skin and causes Merkel cell carcinoma (MCC) in immunocompromised individuals.
Kyle Rapchak, Shiva D Yagobian, Jackson Moore, Michelle Khattri, Masahiro Shuda   +4 more
doaj   +1 more source

HPV-18 transformed cells fail to arrest in G1 in response to quercetin treatment [PDF]

, 2005
Previous work with primary human keratinocytes demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 with concomitant elevation of the cyclin-dependent kinase inhibitor (cdki ...
Alonso-Amelot, Beniston, Beniston, Bjeldanes, Cairney, Campo, Chang, Connolly, Cooper, Davies, de Villiers, Dell, Fazal, Galpin, Gillison, Hawley-Nelson, Hirayama, Ishidate, Jackson, Jones, M.S. Campo, Marliere, Nakayasu, O’Connor, Pecoraro, Pecoraro, Pennie, Plaumann, R.G. Beniston, Stanley, Suzuk, Suzuki, Syrjanen, Thierry, Togawa, Villalobos-Salazar, zur Hausen, zur Hausen   +37 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Human polyomaviruses and cancer: an overview

Clinics, 2018
The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the
José Carlos Mann Prado, Telma Alves Monezi, Aline Teixeira Amorim, Vanesca Lino, Andressa Paladino, Enrique Boccardo   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source