Results 111 to 120 of about 1,789,995 (350)

La relación núcleo-citoplasmática en la diferenciación y transformación celular del epitelio mamario

Revista Chilena de Obstetricia y Ginecología, 2012
Antecedentes: Las células pertenecientes a la línea HC11 son estimuladas tanto a proliferar mediante el Factor de Crecimiento Epidérmico, como a diferenciar estimuladas con dexametasona, insulina y prolactina, dando origen a los tipos celulares HC11 GM y
Ricardo Cornejo U
doaj  

Proteomic analysis reveals LRPAP1 as a key player in the micropapillary pattern metastasis of lung adenocarcinoma

Heliyon
Objectives: Lung adenocarcinomas have different prognoses depending on their histological growth patterns. Micropapillary growth within lung adenocarcinoma, particularly metastasis, is related to dismal prognostic outcome. Metastasis accounts for a major
Hao-jie Yan, Sheng-cheng Lin, Shao-hang Xu, Yu-biao Gao, Bao-jin Zhou, Ruo Zhou, Fu-ming Chen, Fu-rong Li   +7 more
doaj   +1 more source

A model for the epigenetic switch linking inflammation to cell transformation: deterministic and stochastic approaches.

PLoS Computational Biology, 2014
Recently, a molecular pathway linking inflammation to cell transformation has been discovered. This molecular pathway rests on a positive inflammatory feedback loop between NF-κB, Lin28, Let-7 microRNA and IL6, which leads to an epigenetic switch ...
Claude Gérard, Didier Gonze, Frédéric Lemaigre, Béla Novák   +3 more
doaj   +1 more source

transformed cell

Citation: 'transformed cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.16166 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Will Stem Cells Transform Medicine? [PDF]

Baylor University Medical Center Proceedings, 2002
Before beginning this activity, please read the instructions for CMEon p. 241. This page also provides important information on themethod of physician participation, estimated time to complete theeducational activity, medium used for instruction, and dates of re-lease and expiration. The quiz, evaluation form, and certificationappear on pp. 241–243.
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Peripheral Blood T‐Cell Receptor Repertoire Diversity as a Potential Biomarker in the Diagnosis and Treatment Evaluation of Colorectal and Lung Cancers: A Prospective Observational Study

Cancer Medicine
Background T‐cell receptor (TCR) diversity 50 (D50) values could assess peripheral blood (PB) TCR diversity and immunity. This study aimed to evaluate the potential D50 value in the diagnosis and treatment evaluation of colorectal cancer (CRC) and ...
Jilong Ma, Yuanbiao Wang, Zhixin Zhang, Xinyi Cai, Xudong Xiang, Yan Chen, Fengqiong Sun, Jian Dong   +7 more
doaj   +1 more source

p27kip1 Protein Levels Reflect a Nexus of Oncogenic Signaling during Cell Transformation [PDF]

, 2012
Jeffrey Miller, Nancy Yeh, Christoph P. Hofstetter, Doruk Keskin, Andrew S. Goldstein, Andrew Koff   +5 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Long-term follow-up of patients with relapsed/refractory multiple myeloma after BCMA CAR-T-cell therapy

Frontiers in Immunology
BackgroundB-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapy has demonstrated potent short-term efficacy in patients with relapsed/refractory multiple myeloma (R/R MM); however, long-term clinical data remain limited.
Yuanyuan Hao, Yuanyuan Hao, Zhen Wang, Zhen Wang, Lei Zhang, Lei Zhang, Yanliang Bai, Xiaoli Yuan, Jing Yang, Li Jiang, Junwei Niu, Wei Cheng, Wei Li, Zhoufeng Huang, Yuqing Chen, Kai Sun, Kai Sun, Zunmin Zhu, Zunmin Zhu   +18 more
doaj   +1 more source