Results 111 to 120 of about 751,951 (166)

Brief Report: Comprehensive Clinicogenomic Profiling of Small Cell Transformation From EGFR-Mutant NSCLC Informs Potential Therapeutic Targets. [PDF]

open access: yesJTO Clin Res Rep
Zhang B   +35 more
europepmc   +1 more source

Cell Transformation Assays

Current Protocols in Toxicology, 1999
AbstractMorphological transformation of mammalian cells following exposure to a chemical agent is frequently used as a preliminary screen for the carcinogenic potential of the agent. This unit describes a protocol using Syrian hamster embryo (SHE) cells to assay transformation.
M, Costa, J E, Sutherland
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Studies on cell transformation

Somatic Cell Genetics, 1979
Seven different transformation stigmata of the transformed CHO cell line, including morphological characteristics, growth behavior, cell membrane biochemical properties, and failure of fibronectin deposition, are reversed by addition of cAMP derivatives to the medium.
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Unit Cell Transformations

2021
In order to know the exact relationships (in terms of planes, directions, unit cell volumes, etc. both in direct and reciprocal lattices) between the two sets of unit cells such as one primitive to another, primitive to non-primitive or vice-versa, the transformation of one set of indices to another is carried out simply by the use of vector algebra ...
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Spreading of non-transformed and transformed cells

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1984
Mechanisms of cellular reactions responsible for the spreading of non-transformed cultured tissue cells on the surface of various substrata and relationships of these reactions to the control of cell proliferation are reviewed; the special role of the membrane-cytoskeleton interactions leading to extension and attachment of pseudopods is stressed ...
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Unique transforming gene in carcinogen-transformed mouse cells

Nature, 1981
Observations from various biological systems suggest that chemical carcinogens transform cells by causing somatic mutations through interacting with DNA1–5. These observations raise several fundamental questions regarding the nature of the transforming genes that are the target of the carcinogens.
Shilo, B, Weinberg, R A
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Genetic transformation of grapevine cells

Plant Cell Reports, 1989
Biovar 1 strains ofAgrobacterium tumefaciens have been used to transform a cell suspension culture ofVitis vinifera cv. Cabernet Sauvignon. Cocultivation of cultures withAgrobacterium strains bearing either the cointegrate pGV3850::1103neo, or the binary vector pGA474-68, each gave rise to kanamycin resistant tissue.
T J, Baribault   +2 more
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Viral Transformation of Epithelial Cells

2012
Approximately 18% of human cancers have a viral etiology and the majority of these involve transformation of epithelial cells. Viral proteins transform epithelia by inducing alterations in the normal cell growth and differentiation pathways through the targeting of host proteins.
Jennifer A, Regan, Laimonis A, Laimins
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