Results 11 to 20 of about 751,951 (166)
Viruses, 2021 It is suggested that HPV-18 variants from the A lineage have higher oncogenic potential compared to B variants. Some studies show uneven distribution of HPV-18 variants in cervical adenocarcinomas and squamous cell carcinomas.
Emily Montosa Nunes +9 more
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The Emerging Role of miRNAs in HTLV-1 Infection and ATLL Pathogenesis
Viruses, 2015 Human T-cell leukemia virus (HTLV)-1 is a human retrovirus and the etiological agent of adult T-cell leukemia/lymphoma (ATLL), a fatal malignancy of CD4/CD25+ T lymphocytes.
Ramona Moles, Christophe Nicot
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Histologic Transformation in an EGFR-Mutant Lung Cancer in a Filipino Patient treated with Afatinib
Philippine Journal of Pathology, 2019 We report a case of a 64-year-old Filipino male who initially presented with chronic cough, easy fatigability, and weight loss. Work-ups lead to a diagnosis of lung adenocarcinoma with epidermal growth factor receptor (EGFR) exon 19 deletion. Patient was
Steffanie Charlyne Tamayo +6 more
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Expression and cell transformation activity of dynactin‐associated protein isoforms
FEBS Open Bio, 2021 Overexpression of human dynactin‐associated protein isoform a (dynAPa) transforms NIH3T3 cells. DynAPa is a single‐pass transmembrane protein with a carboxy‐terminal region exposed to the outside of cells. According to the NCBI RefSeq database, there may
Xiaobo Yin +12 more
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Establishment of human embryonic stem cell WAe009-A-48 carrying a long QT syndrome mutation in SCN5A
Stem Cell Research, 2021 The long QT syndrome type 3 (LQT3) is currently the 3rd most prevalent of the 15 known types of LQT syndrome. Cardiac events in LQT3 are less frequent than LQT1 and LQT2, but more likely to be fatal.
Xiaofei Yang +3 more
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Cells, 2019 Cadmium (Cd) is a widespread environmental pollutant and carcinogen. Although the exact mechanisms of Cd-induced carcinogenesis remain unclear, previous acute/chronic Cd exposure studies have shown that Cd exerts its cytotoxic and carcinogenic effects ...
Heng Wee Tan +8 more
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A review of protocols for engineering human cardiac organoids
Heliyon, 2023 The use of human cardiac organoids (hCOs) as 3D in vitro models for cardiovascular research has shown great promise. Human pluripotent stem cells (hPSCs) have proven to be a potent source for engineering hCOs.
Fujian Wu +3 more
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Developmental toxicity of embryonic 1-naphthol exposure in zebrafish
Di-san junyi daxue xuebao, 2019 Objective To investigate the toxic effects of embryonic exposure to 1-naphthol (1-NAP) on zebrafish development and explore the possible mechanism. Methods Fertilized zebrafish eggs were exposed to 1-NAP at the concentrations of 40, 80, 160 and 200 μmol ...
REN Pingping +4 more
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Frontiers in Physiology, 2014 Rapid development and deployment of engineered nanomaterials such as carbon nanotubes (CNTs) in various commercial and biomedical applications have raised concerns about their potential adverse health effects, especially their long-term effects which ...
Warangkana eLohcharoenkal +7 more
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Establishment of human embryonic stem cell WAe009-A-74 carrying a Long QT syndrome mutation in KCNH2
Stem Cell Research, 2022 Long-QT syndrome type 2 (LQT2) is a common malignant hereditary arrhythmia. Due to the lack of suitable animal and human models, the pathogenesis of LQT2 caused by human ether-a-go-go-related gene (hERG) deficiency is still unclear.
Lixiang Sun +5 more
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