Cell-free translation of virion RNA from nondefective and transformation-defective Rous sarcoma viruses [PDF]
Tony Pawson+2 more
openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Transformation of a Hamster Cell Line by Adenovirus Type 12
Robert M. McAllister, I. Macpherson
openalex +1 more source
Malignant Transformation of BHK 21 Clone 13 Cells by BK Virus—A Human Papovavirus [PDF]
Eugene O. Major, Giampiero di Mayorca
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Effects of calreticulin mutations on cell transformation and immunity. [PDF]
Desikan H+3 more
europepmc +1 more source
Cell Graph Transformer for Nuclei Classification [PDF]
Nuclei classification is a critical step in computer-aided diagnosis with histopathology images. In the past, various methods have employed graph neural networks (GNN) to analyze cell graphs that model inter-cell relationships by considering nuclei as vertices.
arxiv
Transformation of Nonimmune Lymph Node Cells to State of Transplantation Immunity by RNA
John A. Mannick, Richard H. Ecdahl
openalex +2 more sources
Neoplastic transformation of epithelial cells in whole mammary gland in vitro. [PDF]
Nitin Telang+3 more
openalex +1 more source