Results 221 to 230 of about 816,794 (268)

Transglutaminase in cell proliferation and transformation

Medical Oncology and Tumor Pharmacotherapy, 1988
Transglutaminase (TGase) activity was reduced in intact mitogen-stimulated human peripheral blood lymphocytes (PBL) when compared to intact resting PBL. Moreover, a treatment of the same quiescent immunocompetent cells with purified liver TGase and Ca2+ completely suppressed the mitogen-induced blast transformation.
Metafora S, Peluso G, Ravagnan G, Marchese M, Di Pietro M, Mancini A, Panza N, Fusco A, PORTA, RAFFAELE   +8 more
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The role of calmodulin in cell transformation

Biochemical and Biophysical Research Communications, 1983
Two cell lines transformed with temperature sensitive retroviruses were examined for: their ability to grow in low Ca2+ medium, their calmodulin levels and changes in calmodulin acceptor proteins. Both cell lines grow in low Ca2+ medium at the permissive temperature 34 degrees C while both lines did not replicate at the non-permissive temperature 39 ...
C G, Connor, P B, Moore, R C, Brady, J P, Horn, R B, Arlinghaus, J R, Dedman   +5 more
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Cell Transformation and the Genesis of Cancer

Archives of Environmental Health: An International Journal, 1969
(1969). Cell Transformation and the Genesis of Cancer. Archives of Environmental Health: An International Journal: Vol. 19, No. 2, pp. 157-166.
A, Bendich, E, Borenfreund, Y, Honda, M, Steinglass   +3 more
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Mitochondrial transformation of mammalian cells

Nature, 1982
Resistance to the antibiotics chloramphenicol (CAPr) and efrapeptin (EFr) in mammalian cells is cytoplasmically inherited1,2. We demonstrate here that purified mitochondria obtained from CAPr and EFr cells are taken up by endocytosis and transfer antibiotic resistance to chloramphenicol-(CAPs) and efrapeptin-(EFs) sensitive cells.
M A, Clark, J W, Shay
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Enucleation of normal and transformed cells

Journal of Cellular Physiology, 1987
AbstractA quantitative analysis based on cenrifugal force requirements for enucleation was developed to examine the response of a number of untransformed and transformed cell lines to cytochalasin mediated enucleation. Examination of the extent of cell enucleation as a function of centrifugal force resulted in a series of response curves demonstrating ...
D, Degaetano, M, Schindler
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Reversion in virus-transformed cells

Biochemical Pharmacology, 1971
Abstract The hamster cell line BHK21 can be transformed by the Schmidt-Ruppin strain of Rous sarcoma (RSV-SR) and by polyoma viruses. Revertant cells that have apparently lost the virus genes can be obtained in both cases. These occur spontaneously in the case of RSV-SR transformed cells and following the induction of chromosome loss from near ...
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Physiology of transformed glial cells

Glia, 1995
AbstractMuch of our present knowledge of glial cell function stems from studies of glioma cell lines, both rodent (C6, C6 polyploid, and TR33B) and human (1321N1, 138MG, D384, R‐111, T67, Tp‐301MG, Tp‐483MG, Tp‐378MG, U‐118MG, U‐251MG, U‐373MG, U‐787MG, U‐1242MG, and UC‐11MG). New methods such as patch clamp and Ca2+ imaging have lead to rapid progress
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The Centrosome in Normal and Transformed Cells

DNA and Cell Biology, 2004
The centrosome is a unique organelle that functions as the microtubule organizing center in most animal cells. During cell division, the centrosomes form the poles of the bipolar mitotic spindle. In addition, the centrosomes are also needed for cytokinesis.
Qiang, Wang, Yoshihiko, Hirohashi, Keiji, Furuuchi, Huiwu, Zhao, Qingdu, Liu, Hongtao, Zhang, Ramachandran, Murali, Alan, Berezov, Xiulian, Du, Bin, Li, Mark I, Greene   +10 more
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Viral Transformation of Epithelial Cells

2012
Approximately 18% of human cancers have a viral etiology and the majority of these involve transformation of epithelial cells. Viral proteins transform epithelia by inducing alterations in the normal cell growth and differentiation pathways through the targeting of host proteins.
Jennifer A, Regan, Laimonis A, Laimins
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Transformation of mammalian cells by luteoskyrin

Food and Chemical Toxicology, 1991
The transforming activity of luteoskyrin (LS), a bis-anthraquinoid mycotoxin produced by Penicillium islandicum Sopp., and a hepatocarcinogen in rodents, was examined by an in vitro transformation assay using mouse embryonal Balb/3T3 A31-1-1 cells. The results revealed that LS induced type III foci at 0.5 micrograms/ml, and that the cells selected from
Y, Ueno, W, Habano, H, Yamaguchi, T, Masuda, S, Morimura, K, Nemoto, S, Kojima, F, Tashiro   +7 more
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