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Case report: Acute pancreatitis in lung adenocarcinoma with small cell transformation after multiple line targeted therapy. [PDF]
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Current Protocols in Toxicology, 1999
AbstractMorphological transformation of mammalian cells following exposure to a chemical agent is frequently used as a preliminary screen for the carcinogenic potential of the agent. This unit describes a protocol using Syrian hamster embryo (SHE) cells to assay transformation.
M, Costa, J E, Sutherland
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AbstractMorphological transformation of mammalian cells following exposure to a chemical agent is frequently used as a preliminary screen for the carcinogenic potential of the agent. This unit describes a protocol using Syrian hamster embryo (SHE) cells to assay transformation.
M, Costa, J E, Sutherland
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The Cell Surface and Malignant Transformation
Annual Review of Medicine, 1974A malignant cell has lost many restrictions to which normal cells are subjected. For example, cell division is no longer tightly regulated by cell-cell contact or specific serum factors, serum-mediated hormonal feedback loops are broken, and cell recog nition of neighboring cells no longer leads to maintenance of cell position.
Pollack, R. E., Hough, P. V.
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Spreading of non-transformed and transformed cells
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1984Mechanisms of cellular reactions responsible for the spreading of non-transformed cultured tissue cells on the surface of various substrata and relationships of these reactions to the control of cell proliferation are reviewed; the special role of the membrane-cytoskeleton interactions leading to extension and attachment of pseudopods is stressed ...
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Studies on cell transformation
Somatic Cell Genetics, 1979Seven different transformation stigmata of the transformed CHO cell line, including morphological characteristics, growth behavior, cell membrane biochemical properties, and failure of fibronectin deposition, are reversed by addition of cAMP derivatives to the medium.
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Cellular transformation and the ‘morphologic phenotype’ of transformed cells
Nature, 1978Expression of the product of the transforming gene (src) of RNA tumour viruses promotes growth and usually alters the adhesion, appearance and surface properties of cultured fibroblasts. The latter group of properties termed the 'morphologic phenotype' of transformed cells is largely due to diminished cell-to-substratum adhesion. The role of cyclic AMP,
I, Pastan, M, Willingham
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Oncomodulin in Normal and Transformed Cells
1990The 3-dimensional crystal structure of oncomodulin from X-ray analysis reveals that it is quite similar to that of parvalbumin (F. Ahmed et al., in preparation). Oncomodulin has three domains composed of helix:metal-binding loop:helix arranged in a similar way to parvalbumin (Moews and Kretsinger 1975). This was not unexpected because it was known that
Macmanus, J., Brewer, L., Banville, D.
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Archiv f�r die gesamte Virusforschung, 1965
Studies were made on the effect of various doses of SV40 on the transformation rate of bovine cells, and the transformed cells were studied with regard to the presence of infectious SV40, the presence of the specific complement-fixing (CF) “tumor” antigen, and the transplantability into the autologous host.
H, Diderholm, T, Wesslén
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Studies were made on the effect of various doses of SV40 on the transformation rate of bovine cells, and the transformed cells were studied with regard to the presence of infectious SV40, the presence of the specific complement-fixing (CF) “tumor” antigen, and the transplantability into the autologous host.
H, Diderholm, T, Wesslén
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Mutagensis and cell transformation in cell culture
Methods in Cell Science, 1999The current lack of continuous prawn cell lines suitable for the isolation and growth of prawn viruses is a major setback for diagnosis of viral diseases of prawns; isolation and identification of the causative agents are severely hindered and the development of other diagnostic procedures is slowed.
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Genetic transformation of grapevine cells
Plant Cell Reports, 1989Biovar 1 strains ofAgrobacterium tumefaciens have been used to transform a cell suspension culture ofVitis vinifera cv. Cabernet Sauvignon. Cocultivation of cultures withAgrobacterium strains bearing either the cointegrate pGV3850::1103neo, or the binary vector pGA474-68, each gave rise to kanamycin resistant tissue.
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