Expression and cell transformation activity of dynactin‐associated protein isoforms
Overexpression of human dynactin‐associated protein isoform a (dynAPa) transforms NIH3T3 cells. DynAPa is a single‐pass transmembrane protein with a carboxy‐terminal region exposed to the outside of cells. According to the NCBI RefSeq database, there may
Xiaobo Yin +12 more
doaj +1 more source
An investigation of the RWPE prostate derived family of cell lines using FTIR spectroscopy [PDF]
Interest in developing robust, quicker and easier diagnostic tests for cancer has lead to an increased use of Fourier transform infrared (FTIR) spectroscopy to meet that need.
Baker +34 more
core +3 more sources
Establishment of human embryonic stem cell WAe009-A-48 carrying a long QT syndrome mutation in SCN5A
The long QT syndrome type 3 (LQT3) is currently the 3rd most prevalent of the 15 known types of LQT syndrome. Cardiac events in LQT3 are less frequent than LQT1 and LQT2, but more likely to be fatal.
Xiaofei Yang +3 more
doaj +1 more source
Identification of senescence and death in Emiliania huxleyi and Thalassiosira pseudonana: Cell staining, chlorophyll alterations, and dimethylsulfoniopropionate (DMSP) metabolism [PDF]
We measured membrane permeability, hydrolytic enzyme, and caspase-like activities using fluorescent cell stains to document changes caused by nutrient exhaustion in the coccolithophore Emiliania huxleyi and the diatom Thalassiosira pseudonana, during ...
Airs, Ruth L. +6 more
core +1 more source
Histologic Transformation in an EGFR-Mutant Lung Cancer in a Filipino Patient treated with Afatinib
We report a case of a 64-year-old Filipino male who initially presented with chronic cough, easy fatigability, and weight loss. Work-ups lead to a diagnosis of lung adenocarcinoma with epidermal growth factor receptor (EGFR) exon 19 deletion. Patient was
Steffanie Charlyne Tamayo +6 more
doaj +1 more source
A review of protocols for engineering human cardiac organoids
The use of human cardiac organoids (hCOs) as 3D in vitro models for cardiovascular research has shown great promise. Human pluripotent stem cells (hPSCs) have proven to be a potent source for engineering hCOs.
Fujian Wu +3 more
doaj +1 more source
Oncogenic K-Ras suppresses IP3-dependent Ca2+ release through remodeling of IP3Rs isoform composition and ER luminal Ca2+ levels in colorectal cancer cell lines [PDF]
The GTPase Ras is a molecular switch engaged downstream of G-protein coupled receptors and receptor tyrosine inases that controls multiple cell fate-determining signalling athways.
Bootman, Martin D. +4 more
core +2 more sources
Developmental toxicity of embryonic 1-naphthol exposure in zebrafish
Objective To investigate the toxic effects of embryonic exposure to 1-naphthol (1-NAP) on zebrafish development and explore the possible mechanism. Methods Fertilized zebrafish eggs were exposed to 1-NAP at the concentrations of 40, 80, 160 and 200 μmol ...
REN Pingping +4 more
doaj +1 more source
A thermosyphon-driven hydrothermal flow-through cell for in situ and time-resolved neutron diffraction studies [PDF]
A flow-through cell for hydrothermal phase transformation studies by in situ and time-resolved neutron diffraction has been designed and constructed.
Allan Pring +55 more
core +3 more sources
Rapid development and deployment of engineered nanomaterials such as carbon nanotubes (CNTs) in various commercial and biomedical applications have raised concerns about their potential adverse health effects, especially their long-term effects which ...
Warangkana eLohcharoenkal +7 more
doaj +1 more source

