Results 1 to 10 of about 5,097,186 (131)

Distribution and Levels of Insulin-like Growth Factor 2 Receptor Across Mouse Brain Cell Types [PDF]

Receptors
Background: The insulin-like growth factor 2 receptor (IGF-2R), also known as the cation-independent mannose 6-phosphate receptor (CI-M6PR), is emerging as a critical receptor for brain function and disease. IGF-2R, in fact, plays a key role in long-term
Jessica R. Gaunt, Gokul Manoj, Cristina M. Alberini   +2 more
doaj   +2 more sources

Rostral and caudal basolateral amygdala engage distinct circuits in the prelimbic and infralimbic prefrontal cortex

eLife, 2022
Connections from the basolateral amygdala (BLA) to medial prefrontal cortex (PFC) regulate memory and emotion and become disrupted in neuropsychiatric disorders.
Kasra Manoocheri, Adam G Carter
doaj   +1 more source

Whole animal freeze-fracture scanning electron microscopy: an easy-to-use method to investigate cell type morphology of marine embryos and larvae

Frontiers in Ecology and Evolution, 2023
Morphological and molecular characterization of cell types, organs and individual organisms is essential for understanding the origins of morphogenesis.
Periklis Paganos, Filomena Caccavale, Maria Cocurullo, Enrico D’Aniello, Maria Ina Arnone, Giovanna Benvenuto   +5 more
doaj   +1 more source

Assembling animals: trees, genomes, cells, and contrast to plants

Frontiers in Ecology and Evolution, 2023
The Animal Kingdom is an astonishingly diverse group. Together with plants and fungi is one of the three major lineages of multicellular eukaryotes. Due to anthropocentrism and/or genuine scientific interest, their origin and diversification are pivotal ...
Jordi Paps, Maria Eleonora Rossi, Alexander M. C. Bowles, Marta Álvarez-Presas   +3 more
doaj   +1 more source

A connectome and analysis of the adult Drosophila central brain

eLife, 2020
The neural circuits responsible for animal behavior remain largely unknown. We summarize new methods and present the circuitry of a large fraction of the brain of the fruit fly Drosophila melanogaster.
Louis K Scheffer, C Shan Xu, Michal Januszewski, Zhiyuan Lu, Shin-ya Takemura, Kenneth J Hayworth, Gary B Huang, Kazunori Shinomiya, Jeremy Maitlin-Shepard, Stuart Berg, Jody Clements, Philip M Hubbard, William T Katz, Lowell Umayam, Ting Zhao, David Ackerman, Tim Blakely, John Bogovic, Tom Dolafi, Dagmar Kainmueller, Takashi Kawase, Khaled A Khairy, Laramie Leavitt, Peter H Li, Larry Lindsey, Nicole Neubarth, Donald J Olbris, Hideo Otsuna, Eric T Trautman, Masayoshi Ito, Alexander S Bates, Jens Goldammer, Tanya Wolff, Robert Svirskas, Philipp Schlegel, Erika Neace, Christopher J Knecht, Chelsea X Alvarado, Dennis A Bailey, Samantha Ballinger, Jolanta A Borycz, Brandon S Canino, Natasha Cheatham, Michael Cook, Marisa Dreher, Octave Duclos, Bryon Eubanks, Kelli Fairbanks, Samantha Finley, Nora Forknall, Audrey Francis, Gary Patrick Hopkins, Emily M Joyce, SungJin Kim, Nicole A Kirk, Julie Kovalyak, Shirley A Lauchie, Alanna Lohff, Charli Maldonado, Emily A Manley, Sari McLin, Caroline Mooney, Miatta Ndama, Omotara Ogundeyi, Nneoma Okeoma, Christopher Ordish, Nicholas Padilla, Christopher M Patrick, Tyler Paterson, Elliott E Phillips, Emily M Phillips, Neha Rampally, Caitlin Ribeiro, Madelaine K Robertson, Jon Thomson Rymer, Sean M Ryan, Megan Sammons, Anne K Scott, Ashley L Scott, Aya Shinomiya, Claire Smith, Kelsey Smith, Natalie L Smith, Margaret A Sobeski, Alia Suleiman, Jackie Swift, Satoko Takemura, Iris Talebi, Dorota Tarnogorska, Emily Tenshaw, Temour Tokhi, John J Walsh, Tansy Yang, Jane Anne Horne, Feng Li, Ruchi Parekh, Patricia K Rivlin, Vivek Jayaraman, Marta Costa, Gregory SXE Jefferis, Kei Ito, Stephan Saalfeld, Reed George, Ian A Meinertzhagen, Gerald M Rubin, Harald F Hess, Viren Jain, Stephen M Plaza   +107 more
doaj   +1 more source

Mapping the mind of a fly

eLife, 2020
Scientists have created the most detailed map of the fruit fly brain to date, identifying over 25,000 neurons and 20 million synapses.
Jason Pipkin
doaj   +1 more source

Single Cell Transcriptomic and Chromatin Profiles Suggest Layer Vb Is the Only Layer With Shared Excitatory Cell Types in the Medial and Lateral Entorhinal Cortex

Frontiers in Neural Circuits, 2022
All brain functionality arises from the activity in neural circuits in different anatomical regions. These regions contain different circuits comprising unique cell types.
Stefan Blankvoort, Lene Christin Olsen, Lene Christin Olsen, Lene Christin Olsen, Clifford G. Kentros   +4 more
doaj   +1 more source

Tangential distribution of cell type and direction selectivity in monkey area MT [PDF]

Anais da Academia Brasileira de Ciências, 2020
Abstract: We studied the multiunit responses to moving and static stimuli from 585 cell clusters in area MT using multi-electrode arrays. Our aim was to explore if MT columns exhibit any larger-scale tangential organization or clustering based on their ...
ANTONIA CINIRA M. DIOGO, BRUSS LIMA, JULIANA G. M. SOARES, RICARDO GATTASS   +3 more
doaj   +1 more source

Molecular and spatial profiling of the paraventricular nucleus of the thalamus

eLife, 2023
The paraventricular nucleus of the thalamus (PVT) is known to regulate various cognitive and behavioral processes. However, while functional diversity among PVT circuits has often been linked to cellular differences, the molecular identity and spatial ...
Claire Gao, Chiraag A Gohel, Yan Leng, Jun Ma, David Goldman, Ariel J Levine, Mario A Penzo   +6 more
doaj   +1 more source

Identification of Cell Subpopulations and Interactive Signaling Pathways From a Single-Cell RNA Sequencing Dataset in Osteosarcoma: A Comprehensive Bioinformatics Analysis

Frontiers in Oncology, 2022
Osteosarcoma is a type of highly aggressive bone tumor arising from primitive cells of mesenchymal origin in adults and is associated with a high rate of tumor relapse.
Rong Wu, Xiaojie Dou, Haidong Li, Zhenguo Sun, Heng Li, Yuxin Shen, Wei Weng, Jikang Min   +7 more
doaj   +1 more source