Results 21 to 30 of about 14,829,970 (312)
Triggering of Suicidal Erythrocyte Death by Celecoxib
Toxins, 2013 The selective cyclooxygenase-2 (COX-2) inhibitor celecoxib triggers apoptosis of tumor cells and is thus effective against malignancy. The substance is at least partially effective through mitochondrial depolarization.
Florian Lang +3 more
doaj +1 more source
Mesenchymal cell invasion requires cooperative regulation of persistent microtubule growth by SLAIN2 and CLASP1 [PDF]
, 2016 Microtubules regulate signaling, trafficking, and cell mechanics, but the respective contribution of these functions to cell morphogenesis and migration in 3D matrices is unclear.
Noordstra, Ivar +15 more
core +2 more sources
Brazilian Journal of Medical and Biological Research, 2001 Chick cardiomyocytes, when submitted to hyposmotic swelling, exhibit a partial regulatory volume decrease (RVD). A Ca2+ influx by stretch-activated channels signals a taurine efflux and the RVD at 37°C.
M.M. Souza, R.T. Boyle
doaj +1 more source
Eryptosis: Programmed Death of Nucleus-Free, Iron-Filled Blood Cells
Cells, 2022 Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin, specializing in the transport of oxygen. With a total number of approximately 25 trillion cells per individual, the erythrocyte is the most abundant cell type not only ...
Peter Dreischer +3 more
doaj +1 more source
Triggering of Erythrocyte Death by Triparanol
Toxins, 2015 The cholesterol synthesis inhibitor Triparanol has been shown to trigger apoptosis in several malignancies. Similar to the apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal death characterized by cell shrinkage and cell ...
Arbace Officioso +3 more
doaj +1 more source
Cell Competition and its role in the regulation of cell fitness from development to cancer [PDF]
, 2016 Cell competition is a cell fitness-sensing mechanism conserved from insects to mammals that eliminates those cells that, although viable, are less fit than their neighbors. An important implication of cell competition is that cellular fitness is not only
di gregorio, A, Rodriguez, T, Bowling, S
core +1 more source
Microtubules in 3D cell motility [PDF]
, 2017 Three-dimensional (3D) cell motility underlies essential processes, such as embryonic development, tissue repair and immune surveillance, and is involved in cancer progression. Although the cytoskeleton is a well-studied regulator of cell migration, most
Sub Cell Biology +5 more
core +1 more source
Effect of Thioridazine on Erythrocytes
Toxins, 2013 Background: Thioridazine, a neuroleptic phenothiazine with antimicrobial efficacy is known to trigger anemia. At least in theory, the anemia could result from stimulation of suicidal erythrocyte death or eryptosis, which is characterized by cell ...
Majed Abed +6 more
doaj +1 more source
In Vitro Sensitization of Erythrocytes to Programmed Cell Death Following Baicalein Treatment
Toxins, 2014 The polyphenolic flavonoid Baicalein has been shown to trigger suicidal death or apoptosis of tumor cells and is thus considered for the prevention and treatment of malignancy.
Rosi Bissinger +5 more
doaj +1 more source
Cell Volume Regulation in the Epidermis
Cellular Physiology and Biochemistry, 2021 In order to cope with external stressors such as changes in humidity and temperature or irritating substances, the epidermis as the outermost skin layer forms a continuously renewing and ideally intact protective barrier. Under certain circumstances, this barrier can be impaired and epidermal cells have to counteract cell swelling or shrinkage induced ...
Magdalena Jahn +3 more
openaire +3 more sources