Results 21 to 30 of about 2,039,775 (263)

Effect of Thioridazine on Erythrocytes

open access: yesToxins, 2013
Background: Thioridazine, a neuroleptic phenothiazine with antimicrobial efficacy is known to trigger anemia. At least in theory, the anemia could result from stimulation of suicidal erythrocyte death or eryptosis, which is characterized by cell ...
Majed Abed   +6 more
doaj   +1 more source

In Vitro Sensitization of Erythrocytes to Programmed Cell Death Following Baicalein Treatment

open access: yesToxins, 2014
The polyphenolic flavonoid Baicalein has been shown to trigger suicidal death or apoptosis of tumor cells and is thus considered for the prevention and treatment of malignancy.
Rosi Bissinger   +5 more
doaj   +1 more source

Enhanced Eryptosis Following Gramicidin Exposure

open access: yesToxins, 2015
The peptide antibiotic and ionophore gramicidin has previously been shown to trigger apoptosis of nucleated cells. In analogy to apoptosis, the suicidal death of erythrocytes or eryptosis involves cell shrinkage and cell membrane scrambling with ...
Abaid Malik   +4 more
doaj   +1 more source

Single-Cell Hypertrophy Promotes Contractile Function of Cultured Human Airway Smooth Muscle Cells via Piezo1 and YAP Auto-Regulation

open access: yesCells
Severe asthma is characterized by increased cell volume (hypertrophy) and enhanced contractile function (hyperresponsiveness) of the airway smooth muscle cells (ASMCs). The causative relationship and underlying regulatory mechanisms between them, however,
Kai Ni   +8 more
doaj   +1 more source

Hippocampal and Cortical Pyramidal Neurons Swell in Parallel with Astrocytes during Acute Hypoosmolar Stress

open access: yesFrontiers in Cellular Neuroscience, 2017
Normal nervous system function is critically dependent on the balance of water and ions in the extracellular space (ECS). Pathological reduction in brain interstitial osmolarity results in osmotically-driven flux of water into cells, causing cellular ...
Thomas R. Murphy   +13 more
doaj   +1 more source

On the Distribution of Red Cell Volumes [PDF]

open access: yesBlood, 1968
Abstract A large number of red cell volume distribution curves can be generated on the same sample of blood by manipulating the length of the Coulter Counter aperture and the shape of the red cell. Curves derived from sphered red cells flowing through an aperture 70 x 98µ long, or longer appear to be relatively free from artefacts and ...
openaire   +2 more sources

p38-mediated cell growth and survival drive rapid embryonic wound repair

open access: yesCell Reports, 2021
Summary: Embryos repair wounds rapidly, with no inflammation or scarring, in a process that involves polarization of the actomyosin cytoskeleton. Actomyosin polarization results in the assembly of a contractile cable around the wound that drives wound ...
Gordana Scepanovic   +3 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot   +6 more
wiley   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

The Relationship Between Physical Activity and Left Ventricular Remodeling in Childhood Cancer Survivors Treated With Anthracyclines: A Cross‐Sectional Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Anthracycline‐related cardiac remodeling precedes heart failure in childhood cancer survivors. The objectives of this study were to determine the relationships between patient‐specific factors, moderate‐to‐vigorous physical activity (MVPA), and cardiac remodeling.
Hari K. Narayan   +15 more
wiley   +1 more source

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