Results 31 to 40 of about 14,829,970 (312)

Enhanced Eryptosis Following Gramicidin Exposure

Toxins, 2015
The peptide antibiotic and ionophore gramicidin has previously been shown to trigger apoptosis of nucleated cells. In analogy to apoptosis, the suicidal death of erythrocytes or eryptosis involves cell shrinkage and cell membrane scrambling with ...
Abaid Malik, Rosi Bissinger, Guoxing Liu, Guilai Liu, Florian Lang   +4 more
doaj   +1 more source

Single-Cell Hypertrophy Promotes Contractile Function of Cultured Human Airway Smooth Muscle Cells via Piezo1 and YAP Auto-Regulation

Cells
Severe asthma is characterized by increased cell volume (hypertrophy) and enhanced contractile function (hyperresponsiveness) of the airway smooth muscle cells (ASMCs). The causative relationship and underlying regulatory mechanisms between them, however,
Kai Ni, Bo Che, Rong Gu, Chunhong Wang, Yan Pan, Jingjing Li, Lei Liu, Mingzhi Luo, Linhong Deng   +8 more
doaj   +1 more source

Hippocampal and Cortical Pyramidal Neurons Swell in Parallel with Astrocytes during Acute Hypoosmolar Stress

Frontiers in Cellular Neuroscience, 2017
Normal nervous system function is critically dependent on the balance of water and ions in the extracellular space (ECS). Pathological reduction in brain interstitial osmolarity results in osmotically-driven flux of water into cells, causing cellular ...
Thomas R. Murphy, Thomas R. Murphy, David Davila, David Davila, Nicholas Cuvelier, Nicholas Cuvelier, Leslie R. Young, Leslie R. Young, Kelli Lauderdale, Kelli Lauderdale, Devin K. Binder, Devin K. Binder, Todd A. Fiacco, Todd A. Fiacco   +13 more
doaj   +1 more source

PI3K-C2 alpha Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation [PDF]

, 2018
Insulin resistance is a syndrome that affects multiple insulin target tissues, each having different biological functions regulated by insulin. A remaining question is to mechanistically explain how an insulin target cell/tissue can be insulin resistant ...
Berggren, PO, Leibiger, IB, Paschen, M, Yunn, NO, Lim, JH, Leibiger, B, Ryu, SH, Moede, T, Pereira, T   +8 more
core   +1 more source

Simulated impact trauma and osteoarthritis: the role of cell volume and mechanotransduction [PDF]

, 2013
Health and emotional benefits are linked to participation in exercise, however single-impact load (e.g. trauma) and altered joint loading can cause bone fracture(s) resulting in permanent cartilage damage and increased risk of osteoarthritis (OA).
Nedelcheva, Y.
core   +1 more source

p38-mediated cell growth and survival drive rapid embryonic wound repair

Cell Reports, 2021
Summary: Embryos repair wounds rapidly, with no inflammation or scarring, in a process that involves polarization of the actomyosin cytoskeleton. Actomyosin polarization results in the assembly of a contractile cable around the wound that drives wound ...
Gordana Scepanovic, Miranda Victoria Hunter, Ran Kafri, Rodrigo Fernandez-Gonzalez   +3 more
doaj   +1 more source

On the Distribution of Red Cell Volumes [PDF]

Blood, 1968
Abstract A large number of red cell volume distribution curves can be generated on the same sample of blood by manipulating the length of the Coulter Counter aperture and the shape of the red cell. Curves derived from sphered red cells flowing through an aperture 70 x 98µ long, or longer appear to be relatively free from artefacts and ...
openaire   +2 more sources

Modulation of Peptidoglycan Synthesis by Recycled Cell Wall Tetrapeptides

, 2020
The bacterial cell wall is made of peptidoglycan (PG), a polymer that is essential for the maintenance of cell shape and survival. During growth, bacteria remodel their PG, releasing fragments that are predominantly reinternalized and recycled.
Dorr, Tobias, Cava, Felipe, Hernandez, Sara B.,, Waldor, Matthew K., Hernandez, Sara B., Cava, Felipe,   +5 more
core   +1 more source

Cell cycle analysis of primary sponge cell cultures [PDF]

, 2011
Proliferation of sponge cells is generally measured via cell counts or viability assays. However, more insight into the proliferative state of a sponge cell population can be obtained from the distribution of the cells over the different phases of the ...
Pomponi, S.A., Dirk E. Martens, Shirley A. Pomponi, Klaske J. Schippers, Martens, D.E., Schippers, K.J., Wijffels, R.H., René H. Wijffels   +7 more
core   +1 more source

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition [PDF]

, 2021
Checkpoint inhibitors (CPIs) augment adaptive immunity. Systematic pan-tumor analyses may reveal the relative importance of tumor-cell-intrinsic and microenvironmental features underpinning CPI sensitization.
Turati, Virginia, Rosenthal, R, Saini, SK, Rosenthal, Rachel, Herrero, Javier, Rowan, A, Turajlic, Samra, Litchfield, K, Guerra-Assunção, José Afonso, Turajlic, S, Hellmann, Matthew D., Swanton, C, Saini, Sunil Kumar, Larkin, James, McGranahan, Nicholas, Reading, JL, Puttick, C, Reading, James L., Swanton, Charles, Thakkar, K, Al Bakir, M, Conde, L, Lim, Emilia, Watkins, TBK, Biswas, D, Enver, Tariq, Puttick, Clare, Turati, V, Litchfield, Kevin, Watkins, Thomas B.K., Hellmann, MD, Rowan, Andrew, Lim, E, Biswas, Dhruva, Van Loo, P, Quezada, SA, Guerra-Assunção, JA, Quezada, Sergio A., Bentham, Robert, Herrero, J, Enver, T, Furness, Andrew J.S., Hadrup, Sine R., Conde, Lucia, Hadrup, SR, Abbosh, C, Lee, Se Hoon, Furness, AJS, Lee, S-H, Al Bakir, Maise, Abbosh, Chris, McGranahan, N, Bentham, R, Larkin, J, Van Loo, Peter, Thakkar, Krupa   +55 more
core   +1 more source