Results 51 to 60 of about 14,829,970 (312)

Two homologous Agr-like quorum-sensing systems cooperatively control adherence, cell morphology, and cell viability properties in Lactobacillus plantarum WCFS1 [PDF]

, 2008
A two-component regulatory system of Lactobacillus plantarum, encoded by genes designated lamK and lamR (hpk10 and rrp10), was studied. The lamK and lamR genes encode proteins which are highly homologous to the quorum-sensing histidine kinase LamC and ...
Vos, W.M., de, Kleerebezem, M., Kunuki, Ryoko, Ingham, C.J., Sturme, Mark, Nakayama, J., Vaughan, Elaine, Kunuki, R., Nakayama, Jiro, Sturme, M.H.J., Fujii, Toshio, Kleerebezem, Michiel, Molenaar, D., Fujii, T., Vaughan, E.E., Ingham, Colin, Beerthuyzen, Marke, Molenaar, Douwe, de Vos, Willem, Molenaar, Douwe; id_orcid, de Vos, W.M., Beerthuyzen, M.M.   +21 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages

, 2017
Stem cell engineering and grafting of mesencephalic dopamine (mesDA) neurons is a promising strategy for brain repair in Parkinson's disease (PD). Refinement of differentiation protocols to optimize this approach will require deeper understanding of ...
Perlmann, Thomas,, Storvall, Helena,, Gillberg, L, Perlmann, Thomas., Joodmardi, Eliza, Kirkeby, A, Gillberg, Linda,, Parmar, Malin,, Kirkeby, Agnete, Perlmann, Thomas, Lahti, Laura,, Sandberg, Rickard,, Nolbrant, Sara, Dahl, Lina,, Bjorklund, AK, Kee, N,, Storvall, H, Dahl, L, Kee, Nigel, Lahti, L, Björklund, Åsa K., Volakakis, Nikolaos, Kee, Nigel,, Dahl, Lina, Joodmardi, E, Parmar, Malin, Volakakis, N, Björklund, Åsa K.,, Bjoerklund, Aasa K., Joodmardi, Eliza,, Gillberg, Linda, Lahti, Laura, Storvall, Helena, Volakakis, Nikolaos,, Nolbrant, Sara,, Sandberg, Rickard, Nolbrant, S, Kirkeby, Agnete,   +37 more
core   +1 more source

Cell Volume Regulation in Lymphocytes

Kidney and Blood Pressure Research, 1988
This article reviews what is known about the volume regulatory responses of lymphocytes. We present a discussion of recent data and hypotheses pertaining to the underlying mechanisms in regulatory volume increase (RVI) and regulatory volume decrease (RVD).
C, Deutsch, S C, Lee
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Inflating bacterial cells by increased protein synthesis

Molecular Systems Biology, 2015
Understanding how the homeostasis of cellular size and composition is accomplished by different organisms is an outstanding challenge in biology. For exponentially growing Escherichia coli cells, it is long known that the size of cells exhibits a strong ...
Markus Basan, Manlu Zhu, Xiongfeng Dai, Mya Warren, Daniel Sévin, Yi‐Ping Wang, Terence Hwa   +6 more
doaj   +1 more source

Label-Free Digital Holo-tomographic Microscopy Reveals Virus-Induced Cytopathic Effects in Live Cells

mSphere, 2018
Cytopathic effects (CPEs) are a hallmark of infections. CPEs are difficult to observe due to phototoxicity from classical light microscopy. We report distinct patterns of virus infections in live cells using digital holo-tomographic microscopy (DHTM ...
Artur Yakimovich, Robert Witte, Vardan Andriasyan, Fanny Georgi, Urs F. Greber   +4 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Principles of Cell Volume Regulation

Kidney and Blood Pressure Research, 1988
Cell volume is determined by the content of osmotically active solute (cell osmoles) and the osmolarity of the extracellular fluid. Cell osmoles consist of non-diffusible and diffusible solutes. A large fraction of the diffusible cation content balances negative charges on the non-diffusible solutes.
openaire   +2 more sources

The Biological Significance of Cell Volume

Kidney and Blood Pressure Research, 1993
To survive, cells have to avoid excessive alterations of their volume. To this end, cells have developed a complex machinery of cell volume regulatory mechanisms comprising transport across the cell membrane and metabolism. Upon cell swelling, they loose electrolytes mainly via selective K⁺ channels and unselective ion channels ...
F, Lang, M, Ritter, H, Völkl, D, Häussinger   +3 more
openaire   +2 more sources