Results 71 to 80 of about 15,438,001 (312)
How cell crowding causes cancer cells to spread
eLifeCell crowding causes high-grade breast cancer cells to become more invasive by activating a molecular switch that causes the cells to shrink and spread.
Rui Hua, Jean X Jiang
doaj +1 more source
Frontiers in Microbiology, 2015 Yeast cells are protected by a cell wall that plays an important role in the exchange of substances with the environment. The cell wall structure is dynamic and can adapt to different physiological states or environmental conditions.
Johannes eLiesche +2 more
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Mechanisms and clinical significance of cell volume regulation
, 1998 A wide variety of factors challenge constancy of cell volume. Alterations of cell volume activate diverse cell volume regulatory mechanisms including ion transport, osmolyte accumulation, metabolism and expression of appropriate genes.
HEIDLAND A +13 more
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Simulated impact trauma and osteoarthritis: the role of cell volume and mechanotransduction [PDF]
, 2013 Health and emotional benefits are linked to participation in exercise, however single-impact load (e.g. trauma) and altered joint loading can cause bone fracture(s) resulting in permanent cartilage damage and increased risk of osteoarthritis (OA).
Nedelcheva, Y.
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SEARCH FOR CELL VOLUME SENSORS: AN UPDATE
Бюллетень сибирской медицины, 2013 Cell volume changes affect a plethora of cellular functions including macromolecular synthesis and catabolism, cell proliferation, differentiation and death.
S. N. Orlov, R. Grygorszyk
doaj
GABA not only a neurotransmitter: osmotic regulation by GABAAR signalling
Frontiers in Cellular Neuroscience, 2012 In neurons the anionic channel γ-aminobutyric (GABA) A receptor (GABAAR) plays a central role in mediating both the neurotrophic and neurotransmitter role of GABA. Activation of this receptor by GABA also affects the function of non-neuronal cells in the
Tiziana eCesetti +2 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Relationship of nuclear genome size, cell volume and nuclei volume in endosperm of Sorghum bicolor
Acta Biologica Slovenica, 2015 Endosperm cells of Sorghum bicolor undergo several rounds of endoreplication during seed development, resulting in somatic endopolyploidy with cells containing 3 C to 96 C nuclei (1 C represents the amount of DNA in an unreplicated haploid genome ...
Aleš Kladnik
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source