Results 61 to 70 of about 2,031,505 (263)

Cell Volume Changes and Membrane Ruptures Induced by Hypotonic Electrolyte and Sugar Solutions

Frontiers in Physiology, 2020
The cell volume changes induced by hypotonic electrolyte and sucrose solutions were studied in Chinese-hamster-ovary epithelial cells. The effects in the solutions with osmolarities between 32 and 315 mosM/L and distilled water were analyzed using bright-
Bojan Božič, Špela Zemljič Jokhadar, Špela Zemljič Jokhadar, Luka Kristanc, Gregor Gomišček, Gregor Gomišček   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Species-specific and environment-sensitive functional traits in six steppe plant species with different roles in community

Historia Naturalis Bulgarica
Plant functional traits are often considered as indicators of plant-environment relationship; however, some plant features can be highly taxonomic-specific.
Shinekhuu Tumurjav, Larissa Ivanova, Yurii Rupyshev, Svetlana Migalina, Sergey Bazha, Leonid Ivanov   +5 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Neutrophils actively swell to potentiate rapid migration

eLife
While the involvement of actin polymerization in cell migration is well-established, much less is known about the role of transmembrane water flow in cell motility.
Tamas L Nagy, Evelyn Strickland, Orion D Weiner   +2 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

A single-cell 3D dynamic volume control system for chondrocytes

BioTechniques
In articular cartilage, zone-specific cellular morphology is a typical characteristic of cartilage tissue, which is related with chondrocyte function, inflammation and osteoarthritis (OA).
Qiang Zhang, Yiyao Wang, Yanjun Zhang, Xiaochun Wei, Weiyi Chen, Quanyou Zhang   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Osmolarity‐Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis Pathology

Advanced Science
Osteoarthritis (OA) is a multifactorial degenerative joint disease of which the underlying mechanisms are yet to be fully understood. At the molecular level, multiple factors including altered signaling pathways, epigenetics, metabolic imbalance ...
Kannan Govindaraj, Marieke Meteling, Jeroen vanRooij, Malin Becker, Andre J. vanWijnen, Jeroen J. J. P. vanden Beucken, Yolande F. M. Ramos, Joyce vanMeurs, Janine N. Post, Jeroen Leijten   +9 more
doaj   +1 more source

Rounding up plant cells

International Journal of Plant Biology, 2010
Compared to animal cells, plant cells are typically non-spherical, which may bias morphometric and fluorimetric analyses, including flow cytometry and other approaches used in the study of cellular biodiversity.
Sergio Ochatt, Anne Moessner
doaj   +1 more source