Results 41 to 50 of about 96,711 (247)

Regulation of Cell Wall Biogenesis in Saccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway [PDF]

Genetics, 2011
Abstract The yeast cell wall is a strong, but elastic, structure that is essential not only for the maintenance of cell shape and integrity, but also for progression through the cell cycle. During growth and morphogenesis, and in response to environmental challenges, the cell wall is remodeled in a highly regulated and polarized manner ...
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Protein Interactions of the Mechanosensory Proteins Wsc2 and Wsc3 for Stress Resistance in Saccharomyces cerevisiae

G3: Genes, Genomes, Genetics, 2020
Antifungal drug discovery and design is very challenging because of the considerable similarities in genetic features and metabolic pathways between fungi and humans. However, cell wall composition represents a notable point of divergence.
Vladimir Vélez-Segarra, Sahily González-Crespo, Ednalise Santiago-Cartagena, Luis E. Vázquez-Quiñones, Nelson Martínez-Matías, Yamirelis Otero, Julián J. Zayas, Rafael Siaca, Jeanmadi del Rosario, Inoushka Mejías, José J. Aponte, Noelani C. Collazo, Francisco J. Lasso, Jamie Snider, Matthew Jessulat, Hiroyuki Aoki, Brian C. Rymond, Mohan Babu, Igor Stagljar, José R. Rodríguez-Medina   +19 more
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Micafungin-Induced Cell Wall Damage Stimulates Morphological Changes Consistent with Microcycle Conidiation in Aspergillus nidulans

Journal of Fungi, 2021
Fungal cell wall receptors relay messages about the state of the cell wall to the nucleus through the Cell Wall Integrity Signaling (CWIS) pathway. The ultimate role of the CWIS pathway is to coordinate repair of cell wall damage and to restore normal ...
Samantha Reese, Cynthia Chelius, Wayne Riekhof, Mark R. Marten, Steven D. Harris   +4 more
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Genome‐wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway [PDF]

Molecular Microbiology, 1999
The cell integrity pathway of Saccharomyces cerevisiae monitors cell wall remodelling during growth and differentiation. Additionally, this pathway responds to environmental stresses that challenge the integrity of the cell wall. We conducted a genome‐wide survey of genes whose expression was altered in response to activation of Mpk1/Slt2, the MAP ...
U S, Jung, D E, Levin
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Participation of Candida albicans transcription factor RLM1 in cell wall biogenesis and virulence. [PDF]

PLoS ONE, 2014
Candida albicans cell wall is important for growth and interaction with the environment. RLM1 is one of the putative transcription factors involved in the cell wall integrity pathway, which plays an important role in the maintenance of the cell wall ...
Yolanda Delgado-Silva, Catarina Vaz, Joana Carvalho-Pereira, Catarina Carneiro, Eugénia Nogueira, Alexandra Correia, Laura Carreto, Sónia Silva, Augusto Faustino, Célia Pais, Rui Oliveira, Paula Sampaio   +11 more
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MaAreB, a GATA Transcription Factor, Is Involved in Nitrogen Source Utilization, Stress Tolerances and Virulence in Metarhizium acridum

Journal of Fungi, 2021
The nitrogen catabolite repression (NCR) pathway is involved in nitrogen utilization, in which the global GATA transcription factor AreA plays an indispensable role and has been reported in many fungi. However, relatively few studies are focused on AreB,
Chaochuang Li, Qipei Zhang, Yuxian Xia, Kai Jin   +3 more
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Cross Talk between the Cell Wall Integrity and Cyclic AMP/Protein Kinase A Pathways in Cryptococcus neoformans

mBio, 2014
Cryptococcus neoformans is a fungal pathogen of immunocompromised people that causes fatal meningitis. The fungal cell wall is essential to viability and pathogenesis of C.
Maureen J. Donlin, Rajendra Upadhya, Kimberly J. Gerik, Woei Lam, Laura G. VanArendonk, Charles A. Specht, Neil K. Sharma, Jennifer K. Lodge   +7 more
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The High Osmotic Response and Cell Wall Integrity Pathways Cooperate to Regulate Transcriptional Responses to Zymolyase-induced Cell Wall Stress in Saccharomyces cerevisiae [PDF]

Journal of Biological Chemistry, 2009
The adaptation of Saccharomyces cerevisiae to situations in which cell wall integrity is seriously compromised mainly involves the cell wall integrity (CWI) pathway. However, in a recent work ( Bermejo, C., Rodriguez, E., García, R., Rodríguez-Peña, J. M., Rodríguez de la Concepción, M.
Raúl, García, Jose M, Rodríguez-Peña, Clara, Bermejo, César, Nombela, Javier, Arroyo   +4 more
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The Aspergillus giganteus antifungal protein AFPNN5353activates the cell wall integrity pathway and perturbs calcium homeostasis [PDF]

BMC Microbiology, 2011
Abstract Background The antifungal protein AFPNN5353 is a defensin-like protein of Aspergillus giganteus. It belongs to a group of secretory proteins with low molecular mass, cationic character and a high content of cysteine residues.
Binder, Ulrike, Bencina, Mojca, Eigentler, Andrea, Meyer, Vera, Marx, Florentine   +4 more
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Cdc48 and cofactors Npl4-Ufd1 are important for G1 progression during heat stress by maintaining cell wall integrity in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2011
The ubiquitin-selective chaperone Cdc48, a member of the AAA (ATPase Associated with various cellular Activities) ATPase superfamily, is involved in many processes, including endoplasmic reticulum-associated degradation (ERAD), ubiquitin- and proteasome ...
Meng-Ti Hsieh, Rey-Huei Chen
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