Results 91 to 100 of about 2,959,069 (338)
Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes [PDF]
, 2007 Adhesion molecules of the integrin beta1 family are thought to be involved in the malignant progression renal cell carcinoma (RCC). Still, it is not clear how they contribute to this process.
Achiwa H +10 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Materials Research, 2013 Nanocomposites based on superhydrophilic vertically aligned multi-walled carbon nanotubes (VAMWCNT-O2) and nanohydroxyapatite (nHAp) are of great interest in bone regenerative medicine.
Marcele Florencio Neves +5 more
doaj
Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]
, 1998 The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, A.
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cellular Communication via Adhesion
The FASEB Journal, 2020 Adhesion G Protein‐Coupled Receptors (GPCRs) are cell adhesion proteins that mediate cellular communication and play critical roles in embryonic and neural development. Their mechanisms of action remain poorly understood. In the past several years, three‐dimensional structures of adhesion GPCRs and their ligands have been reported at atomic resolutions
openaire +1 more source
Transmembrane cooperative linkage in cellular adhesion
European Journal of Cell Biology, 2002 Various dynamic cellular activities require precise regulation of extracellular adhesion. Here we propose a simple thermodynamic model that does not depend on affinity regulation of transmembrane adhesion molecules but, rather, is based on the principles of collision-limited reactions. We show that the number of transmembrane adhesion molecules forming
Werner, Baumgartner, Detlev, Drenckhahn
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Morphofunctional characteristics of endothelial cells in coronary atherosclerosis [PDF]
Archives of Biological Sciences, 2011 Atherosclerosis represents a complex disease which encompasses all the components of the vascular wall. Nevertheless, according to all known theories of the pathogenesis of atherosclerosis, the key role in this process belongs to the endothelial cells,
Lačković Vesna +11 more
doaj +1 more source