Results 71 to 80 of about 3,597,969 (327)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Prospects of Justice for Cellular Agriculture: A just Transition or Reinvesting in Unsustainability?

Food Ethics
Transformation in food systems poses new opportunities for improving environmental sustainability and reducing the use of farmed animals. Discussions about transforming current food systems have been centered mostly on replacing animal source proteins ...
Jana Moritz, Rachel Mazac, Mariana Hase Ueta, Niko Räty, Hanna L. Tuomisto, T. Ryynänen   +5 more
semanticscholar   +1 more source

Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle [PDF]

, 2018
peer-reviewedThe genetic mechanisms controlling residual feed intake (RFI) in beef cattle are still largely unknown. Here we performed whole transcriptome analyses to identify differentially expressed (DE) genes and their functional roles in liver ...
Fitzsimmons, Carolyn, Keogh, Kate, Li, Changxi, Mukiibi, Robert, Stothard, Paul, Vinsky, Michael, Waters, Sinead M.   +6 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Possibilities for Engineered Insect Tissue as a Food Source

Frontiers in Sustainable Food Systems, 2019
Due to significant environmental concerns associated with industrial livestock farming, it is vital to accelerate the development of sustainable food production methods.
Natalie R. Rubio, Natalie R. Rubio, Kyle D. Fish, Barry A. Trimmer, David L. Kaplan   +4 more
doaj   +1 more source

The cultural construction of cellular agriculture food: through the lens of the whole-parts framework for meat

Frontiers in Sustainable Food Systems
This essay presents a critical perspective on the nature of what is referred to as “cultured meat” in the public sphere by revisiting the concept of meat in cultural practice.
Aiko Hibino, J. Minari, Kento Takahashi, Yuko Sugiyama, Shinji Kawana   +4 more
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Cell-Based Seafood Production: Regulatory Framework in the United States and Food Safety Considerations

EDIS
In this EDIS publication, we provide information on the current regulatory framework for cell-based seafood production in the United States, food safety considerations, and the path forward for cell-based seafood products to get approved for selling in ...
Rose Omidvar, Razieh Farzad
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Modulation of nutritional composition and aroma volatiles in cultivated pork fat by culture media supplementation

Frontiers in Nutrition
Cultivated meat is emerging as a novel food source with the potential to contribute to a more sustainable and ethical food production system. However, limited research to date has explored the extent to which the nutrition and the aroma of such foods can
Natsu Sugama, Emily T. Lew, Camilo Riquelme-Guzmán, Di Sheng Lee, Xinxin Li, John S. K. Yuen, John S. K. Yuen, Taehwan Lim, Anson Kwan, Run Yi Liu, Yoshene A. Ma, Scott C. Frost, David L. Kaplan   +12 more
doaj   +1 more source