Results 31 to 40 of about 216,120 (296)

Twirling and Whirling: Viscous Dynamics of Rotating Elastica

open access: yes, 1999
Motivated by diverse phenomena in cellular biophysics, including bacterial flagellar motion and DNA transcription and replication, we study the overdamped nonlinear dynamics of a rotationally forced filament with twist and bend elasticity.
A. E. H. Love   +33 more
core   +1 more source

Universal protein fluctuations in populations of microorganisms

open access: yes, 2012
The copy number of any protein fluctuates among cells in a population; characterizing and understanding these fluctuations is a fundamental problem in biophysics.
Braun, Erez   +7 more
core   +1 more source

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction. [PDF]

open access: yes, 2020
The AAA protein Msp1 extracts mislocalized tail-anchored membrane proteins and targets them for degradation, thus maintaining proper cell organization.
Myasnikov, Alexander   +3 more
core   +3 more sources

Mind-life continuity: a qualitative study of conscious experience [PDF]

open access: yes, 2017
There are two fundamental models to understanding the phenomenon of natural life. One is thecomputational model, which is based on the symbolic thinking paradigm. The other is the biologicalorganism model.
Hipólito, Inês, Martins, J.
core   +1 more source

Cellular Biophysics: Bacterial Endospore, Membranes and Random Fluctuation [PDF]

open access: yesCurrent Biology, 2006
Purposeful motion of biological processes can be driven by Brownian motion of macromolecular complexes with one-sided binding biasing movement in one direction: a Brownian ratchet, now proposed to explain membrane motion during a phagocytosis-like process in bacteria.
Lizunov, Vladimir, Zimmerberg, Joshua
openaire   +2 more sources

The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release [PDF]

open access: yes, 2012
Hypothalamic magnocellular neurons release vasopressin and oxytocin not only from their axon terminals into the blood, but also from their somata and dendrites into the extracellular space of the brain, and this can be regulated independently ...
Leng, Gareth, Ludwig, Mike, Tobin, Vicky
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. [PDF]

open access: yes, 2019
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged.
Caballero, Iracema   +10 more
core   +4 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Liver cancer multiomics reveals diverse protein kinase A disruptions convergently produce fibrolamellar hepatocellular carcinoma

open access: yesNature Communications
Fibrolamellar Hepatocellular Carcinoma (FLC) is a rare liver cancer characterized by a fusion oncokinase of the genes DNAJB1 and PRKACA, the catalytic subunit of protein kinase A (PKA).
David Requena   +7 more
doaj   +1 more source

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