Results 11 to 20 of about 155,417 (232)
Lysosome-Mitochondrial Crosstalk in Cellular Stress and Disease
The perception of lysosomes and mitochondria as entirely separate and independent entities that degrade material and produce ATP, respectively, has been challenged in recent years as not only more complex roles for both organelles, but also an ...
Szilvia Kiraly +2 more
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Cellular crosstalk during liver regeneration: unity in diversity [PDF]
The liver is unique in its ability to regenerate from a wide range of injuries and diseases. Liver regeneration centers around hepatocyte proliferation and requires the coordinated actions of nonparenchymal cells, including biliary epithelial cells ...
Wenzhi Shu +5 more
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TLRs in Hepatic Cellular Crosstalk [PDF]
Toll-like receptors (TLRs) are expressed on all major subsets of liver cells. Both exogenous ligands derived from pathogens, and endogenous ligands that are products of cellular injury, engage these receptors and activate aspects of innate immunity ...
Amelie E. Bigorgne, Ian Nicholas Crispe
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Ubiquitin crosstalk connecting cellular processes [PDF]
The polypeptide ubiquitin is used in many processes as different as endocytosis, multivesicular body formation, and regulation of gene transcription. Conjugation of a single ubiquitin moiety is typically used in these processes.
Salomons Florian A +3 more
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Cellular crosstalk during cholestatic liver injury
The functions of the liver are very diverse. From detoxifying blood to storing glucose in the form of glycogen and producing bile to facilitate fat digestion, the liver is a very active and important organ.
Joanne Thomson +4 more
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Macrophage-Derived Exosomal BMPR2 Mediates Alveolar Epithelial Repair and Cellular Crosstalk in Acute Lung Injury [PDF]
Xiang Yun,1– 3 Fei Li,1 Zhen Chen,4 Jiahua Meng,1 Lin Zhang,2,3,5 Juxiang Yuan1 1School of Public Health, North China University of Science and Technology, Tangshan, 063000, People’s Republic of China; 2Clinical Medical Research Center for Women and ...
Yun X +5 more
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GDF2 and BMP10 coordinate liver cellular crosstalk to maintain liver health [PDF]
The liver is the largest solid organ in the body and is primarily composed of hepatocytes (HCs), endothelial cells (ECs), Kupffer cells (KCs), and hepatic stellate cells (HSCs), which spatially interact and cooperate with each other to maintain liver ...
Dianyuan Zhao +12 more
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Mimicking the Dynamic Mechanical ECM Using Engineered Biomaterials to Investigate Cellular Crosstalk
The stiffness of a tissue changes during the lifetime of an individual and is an indicator of age, disease, and pathophysiological conditions [...]
Banani Kundu
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Crosstalk of renal epithelial cells with interstitial fibroblasts plays an important role in kidney pathophysiology. A previous study showed that crosstalk between renal epithelial cells and renal fibroblasts protects against acidosis-induced damage.
Marie-Christin Schulz +5 more
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Roles of extracellular vesicles associated non-coding RNAs in Diabetes Mellitus
Extracellular vesicles (EVs), especially exosomes (50 to 150 nm), have been shown to play important roles in a wide range of physiological and pathological processes, including metabolic diseases such as Diabetes Mellitus (DM).
Benoit R. Gauthier +3 more
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