Results 31 to 40 of about 155,417 (232)
Milk-Derived Extracellular Vesicles in Inter-Organism, Cross-Species Communication and Drug Delivery
Proteomes, 2020 Milk is considered as more than a source of nutrition for infants and is a vector involved in the transfer of bioactive compounds and cells. Milk contains abundant quantities of extracellular vesicles (EVs) that may originate from multiple cellular ...
Rahul Sanwlani +3 more
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Cellular crosstalk in fibrosis: Insights into macrophage and fibroblast dynamics. [PDF]
J Biol ChemPathological fibrosis, the excessive deposition of extracellular matrix and tissue stiffening that causes progressive organ dysfunction, underlies diverse chronic diseases. The fibrotic microenvironment is driven by the dynamic microenvironmental interaction between various cell types; macrophages and fibroblasts play central roles in fibrotic disease ...
Froom ZSCS +2 more
europepmc +3 more sources
OncoImmunology, 2018 Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk.
Yingxin Yu +5 more
doaj +1 more source
The crosstalk of NAD, ROS and autophagy in cellular health and ageing [PDF]
Biogerontology, 2020 AbstractCellular adaptation to various types of stress requires a complex network of steps that altogether lead to reconstitution of redox balance, degradation of damaged macromolecules and restoration of cellular metabolism. Advances in our understanding of the interplay between cellular signalling and signal translation paint a complex picture of ...
Lucia Sedlackova, Viktor I. Korolchuk
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Hepatic Macrophages in Liver Injury
Frontiers in Immunology, 2020 Ample evidence suggests that hepatic macrophages play key roles in the injury and repair mechanisms during liver disease progression. There are two major populations of hepatic macrophages: the liver resident Kupffer cells and the monocyte-derived ...
Zhao Shan, Cynthia Ju
doaj +1 more source
Crosstalk of endoplasmic reticulum exit sites and cellular signaling [PDF]
FEBS Letters, 2019 The synthesis, quality control, and trafficking of a third of the eukaryotic proteome takes place at the endoplasmic reticulum (ER), which is the largest cellular organelle. Thus, biosynthetic trafficking from the ER, although constitutive, has to be tightly controlled.
Federica G. Centonze, Hesso Farhan
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TP53 and MTOR crosstalk to regulate cellular senescence
Aging, 2010 The full spectrum of activities of the tumor suppressor p53 (TP53) has not been completely elucidated yet. Recently, it was demonstrated that TP53 communicates with the metabolic regulator mechanistic target of rapamycin (MTOR) to determine whether stressed cells undergo cell death, reversible quiescence or irreversible senescence, thereby adding yet ...
Kepp, Oliver +2 more
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Frontiers in ImmunologyBackgroundProstate cancer (PCa) presents substantial heterogeneity and unpredictability in its progression. Despite therapeutic advancements, mortality from advanced PCa remains a significant challenge.
Tingting Wu +4 more
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The crosstalk between cellular reprogramming and senescence in aging and regeneration
Experimental Gerontology, 2020 Aging is associated with diminished regenerative capacity and increased risk of chronic diseases. There is now compelling evidence suggests that aging process is reversible. Besides metabolic modification and systematic factors, both senescence elimination and cellular reprogramming showed beneficial effects on tissue regeneration and rejuvenation ...
Chiche, Aurélie, Chen, Cheng, Li, Han
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The role of cellular and molecular neuroimmune crosstalk in gut immunity
Cellular & Molecular Immunology, 2023 AbstractThe gastrointestinal tract is densely innervated by the peripheral nervous system and populated by the immune system. These two systems critically coordinate the sensations of and adaptations to dietary, microbial, and damaging stimuli from the external and internal microenvironment during tissue homeostasis and inflammation. The brain receives
Daping Yang +2 more
openaire +2 more sources