Results 21 to 30 of about 155,417 (232)

Stuck on you: Meninges cellular crosstalk in development. [PDF]

Curr Opin Neurobiol, 2023
The spatial and temporal development of the brain, overlying meninges (fibroblasts, vasculature and immune cells) and calvarium are highly coordinated. In particular, the timing of meningeal fibroblasts into molecularly distinct pia, arachnoid and dura subtypes coincides with key developmental events in the brain and calvarium.
Como CN, Kim S, Siegenthaler J.
europepmc   +3 more sources

CD30-Positive Extracellular Vesicles Enable the Targeting of CD30-Negative DLBCL Cells by the CD30 Antibody-Drug Conjugate Brentuximab Vedotin

Frontiers in Cell and Developmental Biology, 2021
CD30, a member of the TNF receptor superfamily, is selectively expressed on a subset of activated lymphocytes and on malignant cells of certain lymphomas, such as classical Hodgkin Lymphoma (cHL), where it activates critical bystander cells in the tumor ...
Liudmila Lobastova, Liudmila Lobastova, Liudmila Lobastova, Liudmila Lobastova, Marcus Lettau, Marcus Lettau, Felix Babatz, Thais Dolzany de Oliveira, Thais Dolzany de Oliveira, Thais Dolzany de Oliveira, Thais Dolzany de Oliveira, Phuong-Hien Nguyen, Phuong-Hien Nguyen, Phuong-Hien Nguyen, Phuong-Hien Nguyen, Bianca Alves Pauletti, Astrid C. Schauss, Horst Dürkop, Ottmar Janssen, Adriana F. Paes Leme, Michael Hallek, Michael Hallek, Michael Hallek, Michael Hallek, Hinrich P. Hansen, Hinrich P. Hansen, Hinrich P. Hansen, Hinrich P. Hansen   +27 more
doaj   +1 more source

MicroRNA and Protein Cargos of Human Limbal Epithelial Cell-Derived Exosomes and Their Regulatory Roles in Limbal Stromal Cells of Diabetic and Non-Diabetic Corneas

Cells, 2023
Epithelial and stromal/mesenchymal limbal stem cells contribute to corneal homeostasis and cell renewal. Extracellular vesicles (EVs), including exosomes (Exos), can be paracrine mediators of intercellular communication.
Nagendra Verma, Drirh Khare, Adam J. Poe, Cynthia Amador, Sean Ghiam, Andrew Fealy, Shaghaiegh Ebrahimi, Odelia Shadrokh, Xue-Ying Song, Chintda Santiskulvong, Mitra Mastali, Sarah Parker, Aleksandr Stotland, Jennifer E. Van Eyk, Alexander V. Ljubimov, Mehrnoosh Saghizadeh   +15 more
doaj   +1 more source

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

eLife, 2022
Interactions of developing T cells with Aire+ medullary thymic epithelial cells expressing high levels of MHCII molecules (mTEChi) are critical for the induction of central tolerance in the thymus.
Noella Lopes, Nicolas Boucherit, Jérémy C Santamaria, Nathan Provin, Jonathan Charaix, Pierre Ferrier, Matthieu Giraud, Magali Irla   +7 more
doaj   +1 more source

Volatile Compounds Are Involved in Cellular Crosstalk and Upregulation [PDF]

Advanced Biosystems, 2019
AbstractCell–cell cross talk is of great importance in cancer research due to its major role in proliferation, differentiation, migration, and influence on the apoptotic pathway. Different cell–cell communication mechanisms have come mainly from proteomic and genomic approaches. In this paper, a new route is reported for cross talk between cancer cells
Serasanambati, Mamatha, Broza, Yoav Y., Haick, Hossam   +2 more
openaire   +2 more sources

The crosstalk between parenchymal cells and macrophages: A keeper of tissue homeostasis

Frontiers in Immunology, 2022
Non-parenchymal cells (NPCs) and parenchymal cells (PCs) collectively perform tissue-specific functions. PCs play significant roles and continuously adjust the intrinsic functions and metabolism of organs.
Yusi Chen, Li Tang
doaj   +1 more source

Healthy and Osteoarthritis-Affected Joints Facing the Cellular Crosstalk. [PDF]

Int J Mol Sci, 2023
Osteoarthritis (OA) is a chronic, progressive, severely debilitating, and multifactorial joint disease that is recognized as the most common type of arthritis. During the last decade, it shows an incremental global rise in prevalence and incidence. The interaction between etiologic factors that mediate joint degradation has been explored in numerous ...
Semenistaja S, Skuja S, Kadisa A, Groma V.   +3 more
europepmc   +3 more sources

Epithelial–Fibroblast Crosstalk Protects against Acidosis-Induced Inflammatory and Fibrotic Alterations

Biomedicines, 2022
Pathogenesis of chronic kidney disease (CKD) is accompanied by extracellular acidosis inflammation, fibrosis and epithelial-to-mesenchymal transition (EMT). The aim of this study was to assess the influence of acidosis on tubule epithelial cells (NRK-52E)
Marie-Christin Schulz, Linda Voß, Gerald Schwerdt, Michael Gekle   +3 more
doaj   +1 more source

Astrocyte–Oligodendrocyte–Microglia Crosstalk in Astrocytopathies

Frontiers in Cellular Neuroscience, 2020
Defective astrocyte function due to a genetic mutation can have major consequences for microglia and oligodendrocyte physiology, which in turn affects the white matter integrity of the brain.
Dieuwke Maria de Waard, Marianna Bugiani
doaj   +1 more source

Integrin and microtubule crosstalk in the regulation of cellular processes [PDF]

Cellular and Molecular Life Sciences, 2018
Integrins engage components of the extracellular matrix, and in collaboration with other receptors, regulate signaling cascades that impact cell behavior in part by modulating the cell's cytoskeleton. Integrins have long been known to function together with the actin cytoskeleton to promote cell adhesion, migration, and invasion, and with the ...
LaFlamme, Susan E., Mathew-Steiner, Shomita, Singh, Neetu, Colello-Borges, Diane, Nieves, Bethsaida   +4 more
openaire   +2 more sources