Results 21 to 30 of about 1,403,431 (298)

Epigenetics of cellular reprogramming [PDF]

Current Opinion in Genetics & Development, 2013
Cells are constantly changing their state of equilibrium in response to internal and external stimuli. These changes in cell identity are driven by highly coordinated modulation of gene expression. This coordinated regulation is achieved in large part due to changes in the structure and composition of the chromatin, driven by epigenetic modulators ...
Krishnakumar, Raga, Blelloch, Robert H
openaire   +4 more sources

Exopolysaccharide of Enterococcus faecium L15 promotes the osteogenic differentiation of human dental pulp stem cells via p38 MAPK pathway

Stem Cell Research & Therapy, 2022
Background Bone has important functions in the body. Several researchers have reported that the polysaccharides and lipopolysaccharide derived from microbes can promote osteogenic differentiation of stem cells.
Hyewon Kim, Naeun Oh, Mijin Kwon, Oh-Hee Kwon, Seockmo Ku, Jeongmin Seo, Sangho Roh   +6 more
doaj   +1 more source

High Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues

Antioxidants, 2021
Extracellular vesicles (EVs) are paracrine factors that mediate stem cell therapeutics. We aimed at evaluating the possible therapeutic and esthetic applications of EVs prepared from the waste human facial tissue-derived orbicularis oculi muscle stem ...
Kyung Min Lim, Ahmed Abdal Dayem, Yujin Choi, Yoonjoo Lee, Jongyub An, Minchan Gil, Soobin Lee, Hee Jeong Kwak, Balachandar Vellingirl, Hyun Jin Shin, Ssang-Goo Cho   +10 more
doaj   +1 more source

Ketocarotenoid production in tomato triggers metabolic reprogramming and cellular adaptation: The quest for homeostasis [PDF]

, 2023
Plants are sessile and therefore have developed an extraordinary capacity to adapt to external signals. Here, the focus is on the plasticity of the plant cell to respond to new intracellular cues.
Nogueira, M., Lewinsohn, E., Price, E. J., Fraser, P. D., Menard, G. N., Eastmond, P. J., Venter, E., Bar, E., Enfissi, E. M. A.   +8 more
core   +1 more source

Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals

Genome Biology, 2021
Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X ...
Irene Talon, Adrian Janiszewski, Bart Theeuwes, Thomas Lefevre, Juan Song, Greet Bervoets, Lotte Vanheer, Natalie De Geest, Suresh Poovathingal, Ryan Allsop, Jean-Christophe Marine, Florian Rambow, Thierry Voet, Vincent Pasque   +13 more
doaj   +1 more source

A Rho Kinase (ROCK) Inhibitor, Y-27632, Inhibits the Dissociation-Induced Cell Death of Salivary Gland Stem Cells

Molecules, 2021
Salivary gland stem cells (SGSCs) are potential cell sources for the treatment of salivary gland diseases. The control of cell survival is an essential factor for applying stem cells to regenerative medicine or stem cell-based research.
Kichul Kim, Sol Min, Daehwan Kim, Hyewon Kim, Sangho Roh   +4 more
doaj   +1 more source

Unleashing Ascl1 Exploring Cross-Lineage Potential in Reprogramming and Regenerative Frontiers

, 2023
In the era of stem cell research and regenerative medicine, understanding the regulatory networks that drive cellular reprogramming is fundamental.
Lund University., Echegaray, Camila Vazquez,   +1 more
core   +1 more source

Cellular reprogramming in skin cancer [PDF]

Seminars in Cancer Biology, 2015
Early primitive stem cells have long been viewed as the cancer cells of origin (tumor initiating target cells) due to their intrinsic features of self-renewal and longevity. However, emerging evidence suggests a surprising capacity for normal committed cells to function as reserve stem cells upon reprogramming as a consequence of tissue damage ...
Song, Ihn Young, Balmain, Allan
openaire   +4 more sources

Anti-Cancer Effects of Lactobacillus plantarum L-14 Cell-Free Extract on Human Malignant Melanoma A375 Cells

Molecules, 2020
Human malignant melanoma is the most aggressive type of skin cancer with high metastatic ability. Despite several traditional therapies, the mortality rate remains high. Lactobacillus plantarum (L.
Jaehyun Park, Mijin Kwon, Jaehoon Lee, Sangkyu Park, Jeongmin Seo, Sangho Roh   +5 more
doaj   +1 more source

Role of the cytoskeleton in cellular reprogramming: effects of biophysical and biochemical factors [PDF]

Frontiers in Molecular Biosciences
Momotyuk E, Ebrahim N, Shakirova K, Dashinimaev E.   +3 more
exaly   +2 more sources