Results 21 to 30 of about 154,639 (265)
The Journal of Reproduction and Development, 2019 Historically, it had been widely accepted that the female mammalian ovary contained a limited number of oocytes that would reduce over time, without the possibility of replenishment. However, recent studies have suggested that female germline stem cells (
Huy-Hoang NGUYEN +4 more
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Biology, 2023 Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) can differentiate into various tissues and are an essential source of various disease models and therapeutics.
Sejong Kim +9 more
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Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology [PDF]
Aging CellAlejandro Ocampo, Patrick Paine
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Cells, 2022 Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works as a survival mechanism that allows the generation of metabolic ...
Laura Gómez-Virgilio +11 more
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Transcriptional reprogramming in cellular quiescence [PDF]
RNA Biology, 2017 Most cells in nature are not actively dividing, yet are able to return to the cell cycle given the appropriate environmental signals. There is now ample evidence that quiescent G0 cells are not shut-down but still metabolically and transcriptionally active.
Roche, Benjamin +2 more
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Journal of Animal Reproduction and Biotechnology, 2018 Hedgehog (Hh) pathway plays a key role in development from invertebrate to vertebrate. It is known to be involved in cell differentiation, polarity, proliferation, including the development of vertebrate limb and the establishment of flies’ body plan. To
Jaehyun Park +4 more
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Molecular Roadblocks for Cellular Reprogramming [PDF]
Molecular Cell, 2012 During development, diverse cellular identities are established and maintained in the embryo. Although remarkably robust in vivo, cellular identities can be manipulated using experimental techniques. Lineage reprogramming is an emerging field at the intersection of developmental and stem cell biology in which a somatic cell is stably reprogrammed into ...
Vierbuchen, Thomas, Wernig, Marius
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Circulation: Heart Failure, 2013 The hearts of lower vertebrates have remarkable regenerative capacity.1 Neonatal mouse hearts are also capable of repairing damaged myocardium; however, this capacity is lost barely 2 weeks after birth.2 The human adult myocardium is replenished throughout life,3 and studies suggest that this occurs as a result of division of existing cardiomyocytes,4 ...
Anthony J, White +3 more
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The Journal of Reproduction and DevelopmentThe enzymatic isolation of preantral follicles (PAFs) is considered the most efficient method for retrieving a large number of intact follicles, offering significant advantages in terms of yield and processing time.
Ba Anh My LE +10 more
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Journal of Animal Reproduction and Biotechnology, 2018 Polo-like kinase 1 (Plk1) has been known to be a critical element in cell division including centrosome maturation, cytokinesis and spindle formation in somatic, cancer, and mammalian embryonic cells.
Jeonghyeon Moon, Sangho Roh
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