Results 21 to 30 of about 233,840 (301)
Journal of Translational Medicine, 2023 Background The incidence of bladder cancer (BCa) is approximately four times higher in men than in women. To develop effective BCa treatments, there is an urgent need to understand the differences in the BCa control mechanisms based on gender. Our recent
Jaekwon Seok +6 more
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Stem Cell Research, 2022 Charcot-Marie-Tooth type 4B3 (CMT4B3) is a rare subtype of hereditary neuropathy associated with variants in the MTMR5/SBF1 gene. Herein, we report the generation and characterization of a hiPSC line from a 12-year-old Italian girl with early onset ...
Elisa Maria Turco +12 more
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The Journal of Reproduction and Development, 2019 Historically, it had been widely accepted that the female mammalian ovary contained a limited number of oocytes that would reduce over time, without the possibility of replenishment. However, recent studies have suggested that female germline stem cells (
Huy-Hoang NGUYEN +4 more
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Pluripotent Stem Cells for Spinal Cord Injury Repair
Cells, 2021 Spinal cord injury (SCI) is a devastating condition of the central nervous system that strongly reduces the patient’s quality of life and has large financial costs for the healthcare system.
Maria Martin-Lopez +2 more
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Gain-of-function oncogenic mutations in TP53 enhance defined factor-mediated cellular reprogramming [PDF]
, 2011 Cancer is a disorder with various genetic and epigenetic alterations. Genetic alterations such as mutations, i.e., substitutions, amplifications, and deletions of nucleotide sequences, are largely irreversible, whereas epigenetic alterations can be ...
Dyah Laksmi Dewi +9 more
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Epigenetic impairments in development of parthenogenetic preimplantation mouse embryos
The Journal of Reproduction and Development, 2018 Parthenogenesis is an activation process of oocytes that occur without the participation of sperm. Evidence suggests that normal development of embryos requires proper expression of several imprinted genes inherited from both the paternal and maternal ...
Ngan Thi Kim HO +3 more
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Biology, 2023 Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) can differentiate into various tissues and are an essential source of various disease models and therapeutics.
Sejong Kim +9 more
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A stochastic model dissects cell states in biological transition processes [PDF]
, 2013 Many biological processes, including differentiation, reprogramming, and disease transformations, involve transitions of cells through distinct states.
Armond, Jonathan W. +6 more
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Circulation: Heart Failure, 2013 The hearts of lower vertebrates have remarkable regenerative capacity.1 Neonatal mouse hearts are also capable of repairing damaged myocardium; however, this capacity is lost barely 2 weeks after birth.2 The human adult myocardium is replenished throughout life,3 and studies suggest that this occurs as a result of division of existing cardiomyocytes,4 ...
Anthony J, White +3 more
openaire +2 more sources
Cells, 2022 Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works as a survival mechanism that allows the generation of metabolic ...
Laura Gómez-Virgilio +11 more
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