Results 171 to 180 of about 4,791 (192)

Carbohydrate Depolymerization by Intricate Cellulosomal Systems

2023
Cellulosomes are multi-enzymatic nanomachines that have been fine-tuned through evolution to efficiently deconstruct plant biomass. Integration of cellulosomal components occurs via highly ordered protein-protein interactions between the various enzyme-borne dockerin modules and the multiple copies of the cohesin modules located on the scaffoldin ...
Sarah Moraïs, Johanna Stern, Lior Artzi, Carlos M. G. A. Fontes, Edward A. Bayer, Itzhak Mizrahi   +5 more
openaire   +2 more sources

Cellulosomes: Highly Efficient Cellulolytic Complexes

2020
Cellulosomes are elaborate multienzyme complexes capable of efficiently deconstructing lignocellulosic substrates, produced by cellulolytic anaerobic microorganisms, colonizing a large variety of ecological niches. These macromolecular structures have a modular architecture and are composed of two main elements: the cohesin-bearing scaffoldins, which ...
Victor D, Alves, Carlos M G A, Fontes, Pedro, Bule   +2 more
openaire   +2 more sources

Advances in consolidated bioprocessing using synthetic cellulosomes

Current Opinion in Biotechnology, 2022
The primary obstacle impeding the more widespread use of biomass for energy and chemical production is the absence of a low-cost technology for overcoming their recalcitrant nature. It has been shown that the overall cost can be reduced by using a 'consolidated' bioprocessing (CBP) approach, in which enzyme production, biomass hydrolysis, and sugar ...
Shen-Long, Tsai, Qing, Sun, Wilfred, Chen   +2 more
openaire   +2 more sources

Dissolved xylan inhibits cellulosome-based saccharification by binding to the key cellulosomal component of Clostridium thermocellum

International Journal of Biological Macromolecules, 2022
Polysaccharides derived from lignocellulose are promising sustainable carbon sources. Cellulosome is a supramolecular machine integrating multi-function enzymes for effective lignocellulose bio-saccharification. However, how various non-cellulose components of lignocellulose affect the cellulosomal saccharification is hitherto unclear. This study first
Chao, Chen, Kuan, Qi, Fang, Chi, Xiaojin, Song, Yingang, Feng, Qiu, Cui, Ya-Jun, Liu   +6 more
openaire   +2 more sources

Carbohydrate Depolymerization by Intricate Cellulosomal Systems

2017
Cellulosomes are multi-enzymatic nanomachines that have been fine-tuned through evolution to efficiently deconstruct plant biomass. Integration of cellulosomal components occurs via highly ordered protein-protein interactions between the various enzyme-borne dockerin modules and the multiple copies of the cohesin modules located on the scaffoldin ...
Johanna, Stern, Lior, Artzi, Sarah, Moraïs, Carlos M G A, Fontes, Edward A, Bayer   +4 more
openaire   +2 more sources

Cellulosome-like entities inBacteroides cellulosolvens

Current Microbiology, 1991
Cellulosome-like complexes were identified in the broth and sonic extracts of cellobiose-and cellulose-grown cells ofBacteroides cellulosolvens. The extracellular fractions contained three to four major polypeptides and several minor polypeptide bands that were localized in two major gel filtration peaks indicating average molecular weights of about ...
Raphael Lamed, Ely Morag (Morgenstern), Orly Mor-Yosef, Edward A. Bayer   +3 more
openaire   +1 more source

Cellulosomes from Clostridium thermocellum

1988
Publisher Summary Biomass in the form of cellulose is the major constituent of plant matter, thereby comprising the earth's most abundant natural organic resource. Although the repeating unit of this biopolymer is a simple disaccharide (cellobiose), cellulose fibrils are organized into a complicated paracrystalline state.
Raphael Lamed, Edward A. Bayer
openaire   +1 more source

Cellulosome and noncellulosomal cellulases of Clostridium cellulovorans

Extremophiles, 1998
This paper reviews the properties of the cellulosome and noncellulosome cellulases produced by Clostridium cellulovorans, an anaerobic, mesophilic, spore-forming microorganism that produces copious amounts of cellulase. The three major subunits of the cellulosome, CbpA, exoglucanase S (ExgS), and P100, are described, as well as the properties of the ...
R H, Doi, J S, Park, C C, Liu, L M, Malburg, Y, Tamaru, A, Ichiishi, A, Ibrahim   +6 more
openaire   +2 more sources

Cellulosomes: bacterial nanomachines for dismantling plant polysaccharides

Nature Reviews Microbiology, 2016
Cellulosomes are multienzyme complexes that are produced by anaerobic cellulolytic bacteria for the degradation of lignocellulosic biomass. They comprise a complex of scaffoldin, which is the structural subunit, and various enzymatic subunits. The intersubunit interactions in these multienzyme complexes are mediated by cohesin and dockerin modules ...
Lior, Artzi, Edward A, Bayer, Sarah, Moraïs   +2 more
openaire   +2 more sources

The cellulosome — A treasure-trove for biotechnology

Trends in Biotechnology, 1994
The cellulases of many cellulolytic bacteria are organized into discrete multienzyme complexes, called cellulosomes. The multiple subunits of cellulosomes are composed of numerous functional domains, which interact with each other and with the cellulosic substrate.
E A, Bayer, E, Morag, R, Lamed
openaire   +2 more sources