Results 51 to 60 of about 7,373 (166)

Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort

Archives of Gerontology and Geriatrics Plus
Aim: Centenarians represent a successful model of biological aging that is becoming increasingly common but still largely unknown. Data about centenarians in Colombia is scarce.
Ivan David Lozada-Martinez, Juan Sebastian Marín, Sandra Milena Castelblanco-Toro, Enrique A Mazenett-Granados, John Fredy Suárez, Mauricio Sarmiento, Juan-Manuel Anaya   +6 more
doaj   +1 more source

Reflections on Gerontological Nursing Over the Past 50 Years

Journal of Advanced Nursing, EarlyView.
Wendy Moyle
wiley   +1 more source

Masticatory Function in Elderly Individuals Living in Long‐Term Care Facilities in Brazil: Associations Between Objective and Subjective Measurements

Journal of Oral Rehabilitation, Volume 53, Issue 3, Page 761-769, March 2026.
Objective and subjective masticatory functions were associated, but their related factors differed, highlighting the importance of considering both objective and self‐perceived indicators when assessing masticatory dysfunction in LTCF residents.
Lorena Tavares Gama, Mariana Marinho Davino de Medeiros, Yuri Wanderley Cavalcanti, Mario Augusto Brondani, Renata Cunha Matheus Rodrigues Garcia   +4 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, Volume 600, Issue 4, Page 392-417, February 2026.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Reproductive behaviour and longevity: Evidence from Chinese centenarians

Homo, 2023
With the implementation of the three-child policy in China, the debate between fertility and health and longevity has again become a hot topic in the era of increasing ageing. This study aimed to explore the association between reproductive behaviour and
Shuo Zhang, Si-qing Zhang, Hua-lei Yang, Jia-hao Wang, Yuan-yang Wu   +4 more
doaj   +1 more source

Hainan Longevity Model, Senile Degeneration, Cognitive Disability and Healthy Longevity

AGING MEDICINE, Volume 9, Issue 1, Page 67-81, February 2026.
Investigating centenarians who exemplify healthy longevity can aid in formulating preventive strategies aimed at achieving health and extending lifespan in the context of population aging. Hainan longevity model (HLM) plays key roles in promoting healthy longevity and provides scientific evidence for achieving healthy longevity in the older population.
Shihui Fu, Jiacai Lin, Qianshuo Liu, Lianbo Gao, Zhirui Li, Feng Lin, Leixing Xie, Xiong Liu, Wenkai Xiao, Qiwei Zhu, Fan Wang, Jin Zheng, Yali Zhao, Xiaolei Chen, Yao Yao, Long Feng   +15 more
wiley   +1 more source

From consortia discovery to biotech creation: An innovative approach to next‐gen Alzheimer's drugs

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease (AD) research has entered a new era where public‐private partnerships are reigniting the pursuit of disease‐modifying therapies targeting mechanisms beyond amyloid and tau. This perspective outlines how Monument Biosciences was founded to advance novel therapies by translating National Institutes of Health (NIH) ‐supported ...
Sarah F. Giardina, Alexander Culver, Chandrama Ahmed, Christian Mirescu, Adrian L. Oblak, Jared Brosch, W. Brent Clayton, Jeffrey L. Dage, Bruce T. Lamb, Timothy I. Richardson, Derek Small, Alan D. Palkowitz   +11 more
wiley   +1 more source

The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring

BMC Genomics, 2007
Background Studies on heteroplasmy occurring in the mitochondrial DNA (mtDNA) control region (CR) in leukocytes of centenarians and younger subjects have shown that the C150T somatic transition is over-represented in centenarians.
Maletta Raffaele, Feraco Emidio, Mari Vincenzo, Bellizzi Dina, Dato Serena, Romeo Giuseppe, Scornaienchi Vittorio, Passarino Giuseppe, Rose Giuseppina, Bruni Amalia, Franceschi Claudio, De Benedictis Giovanna   +11 more
doaj   +1 more source

RBFOX1 association with age at onset of Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Genetic contributors to early onset Alzheimer's disease (AD) beyond APP and PSEN1/2 remain unknown. Identifying novel loci may reveal disease mechanisms and therapeutic targets. We investigated genetic variants influencing age at onset in early onset families from the Long‐Life Family Study (LLFS).
Laura Xicota, Rong Cheng, Stacy L. Andersen, Joseph M. Zmuda, Mary Wojczynski, Mary F. Feitosa, Joseph Bradley, Carlos Cruchaga, Alex G. Contreras, Timothy J. Hohman, Dolly Reyes‐Dumeyer, Badri V. Vardarajan, Stephanie Cosentino, Richard Mayeux, Joseph H. Lee, Sandra Barral, the Long‐Life Family Study (LLFS), Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA), and The National Institute on Aging Alzheimer's Disease Family Based Study (NIA‐LOAD FBS)   +18 more
wiley   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

Aging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá, Rosario Ortolá, Mercedes Sotos‐Prieto, Fernando Rodríguez‐Artalejo, Andrés Moya, Susana Ruiz‐Ruiz   +5 more
wiley   +1 more source