Results 101 to 110 of about 151,906 (302)

Cerebral venous thrombosis in non-bacterial infections: a systematic review

BMC Neurology
Background This systematic review summarizes evidence on cerebral venous thrombosis (CVT) following non-bacterial (viral, fungal, parasitic) infections, excluding COVID-19, by describing etiology, clinical features, management, and outcomes.
Matheus Campos Medeiros, Ezequias Batista Martins, Lusiele Guaraldo, Guilherme Amaral Calvet   +3 more
doaj   +1 more source

CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems

Frontiers in Molecular Neuroscience, 2019
The options available for genetic modification of cells of the central nervous system (CNS) have greatly increased in the last decade. The current panoply of viral and nonviral vectors provides multifunctional platforms to deliver expression cassettes to
Danila del Rio, Bertrand Beucher, Marina Lavigne, Amani Wehbi, Iria Gonzalez Dopeso-Reyes, Isabella Saggio, Isabella Saggio, Eric J. Kremer   +7 more
doaj   +1 more source

Distribution of Bovine Virus Diarrhoea Viral Antigens in the Central Nervous System of Cattle with Various Congenital Manifestations*

, 1992
Distribution of bovine viral diarrhoea virus (BVDV) antigens in the central nervous system (CNS) of 26 cattle persistently BVDV infected, 11 cattle with mucosal disease (MD), and 32 calves with congenital brain malformations was studied using monoclonal ...
Moennig, V., Liess, B., V. Moennig, B. Liess, Trautwein, G., Fernández Rodríguez, Antonio Jesús, A. Fernandez, T. Wöhrmann, M. Hewicker‐Trautwein, Wöhrmann, T., Hewicker‐Trautwein, M., G. Trautwein   +11 more
core   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

PECULIARITIES OF AMINO ACID METABOLISM IN SERUM AND CEREBROSPINAL FLUID OF PATIENTS WITH CHRONIC VIRAL ENCEPHALITIS WITH CONVULSIVE SYNDROME

Эпилепсия и пароксизмальные состояния, 2016
: a viral infection of the central nervous system is a group of infectious diseases of high infectiousness and mortality in all age groups. Over the past decade, the structure of the viral lesions replaced polio and western encephalitis came slow and ...
N. F. Philippovich, N. V. Staheyko
doaj  

Immunohistochemical analysis of MMP-9, MMP-2 and TIMP-1, TIMP-2 expression in the central nervous system following infection with viral and bacterial meningitis.

, 2009
Matrix metalloproteinases (MMPs) are capable of degrading components of the basal lamina of cerebral vessels, thereby disrupting the blood-brain barrier and inducing leukocyte recruitment.
Sulik, Artur; Department of Pediatric Infectious Diseases, Medical University of Białystok, Poland, Chyczewski, Lech   +1 more
core   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Interferon Gamma: Influence on Neural Stem Cell Function in Neurodegenerative and Neuroinflammatory Disease

Clinical Medicine Insights: Pathology, 2016
Interferon-gamma (IFNγ), a pleiotropic cytokine, is expressed in diverse neurodegenerative and neuroinflammatory conditions. Its protective mechanisms are well documented during viral infections in the brain, where IFNγ mediates non-cytolytic viral ...
Apurva Kulkarni, Priya Ganesan, Lauren A. O'Donnell   +2 more
doaj   +1 more source

Investigation of Bacterial and Viral Etiology in Community Acquired Central Nervous System Infections with Molecular Methods

, 2017
In this multicenter prospective cohort study, it was aimed to evaluate the bacterial and viral etiology in community-acquired central nervous system infections by standart bacteriological culture and multiplex polymerase chain reaction (PCR) methods ...
Alper TÜNGER, Oğuz Reşat SİPAHİ, Şebnem ŞENOL, ALP ÇAVUŞ, SEMA, Gazi, Horu, Isikgoz Tasbakan, Meltem, Cavus, Sema Alp, Sercan ULUSOY, Hörü GAZİ, Sabri ATALAY, Sipahi, Oguz Resat, Bahar ÖRMEN, Kose, Sukran, Gulay, Zeynep, Senol, Sebnem, Meltem IŞIKGÖZ TAŞBAKAN, Şükran KÖSE, Zeynep GÜLAY, Sema ALP ÇAVUŞ, Yamazhan, Tansu, Kahraman, Hasip, Hüsnü PULLUKÇU, Hasip KAHRAMAN, Tansu YAMAZHAN, Ulusoy, Sercan, Tunger, Alper, Atalay, Sabri, Turker, Nesrin, Meltem AVCI, Nesrin TÜRKER, Pullukcu, Husnu, Avci, Meltem, Ormen, Bahar   +32 more
core   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source