Results 31 to 40 of about 151,906 (302)

Pellino Proteins in Viral Immunity and Pathogenesis

, 2023
Pellino proteins are a family of evolutionarily conserved ubiquitin ligases involved in intracellular signaling in a wide range of cell types. They are essential for microbe detection and the initiation of innate and adaptive immune responses.
Liselotte E. Jensen
core   +1 more source

Varicella complications: Is it time to consider a routine varicella vaccination? [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. Varicella is a common and benign disease of childhood. Complications are rare, but in some patients, even without risk factors, severe, life threatening complications could be seen.
Dulović Olga, Gvozdenović Eleonora, Nikolić Jelena, Radovanović-Spurnić Aleksandra, Katanić Nataša, Kovačević-Pavićević Dragana   +5 more
doaj   +1 more source

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more [PDF]

, 2012
B cells and antibodies constitute an important element in different inflammatory diseases of the central nervous system (CNS). Autoantibodies can serve as a biomarker to identify disease subgroups and may in addition contribute to the pathogenic process.
Mayer, Marie Cathrin, Meinl, Edgar, Marie Cathrin Mayer, Edgar Meinl, Meinl, E., Mayer, M.   +5 more
core   +1 more source

Molecular Pathogenicity of Enteroviruses Causing Neurological Disease

Frontiers in Microbiology, 2020
Enteroviruses are single-stranded positive-sense RNA viruses that primarily cause self-limiting gastrointestinal or respiratory illness. In some cases, these viruses can invade the central nervous system, causing life-threatening neurological diseases ...
Anna Majer, Alan McGreevy, Alan McGreevy, Alan McGreevy, Timothy F. Booth, Timothy F. Booth   +5 more
doaj   +1 more source

The retrospective data analysis on the pedigree of nervous system diseases in children

Scientific Reports, 2023
Nowadays, the development of diagnosis and treatment technology is constantly changing the pedigree and classification of nervous system diseases. Analyzing changes in earlier disease pedigrees can help us understand the changes involved in disease ...
Xiaohui Liu, Huanxi Chen, Xiansi Ma, Hongjia Yu, Haiyan Yang, Liang Ai, Qing Liu, Liwen Wu   +7 more
doaj   +1 more source

Chemokines and viral diseases of the central nervous system

, 2001
This chapter discusses chemokines and their receptors in the evolution of viral infectious diseases of the central nervous system (CNS). Infection of the human CNS with many different viruses or infection of the rodent CNS induces vigorous host-inflammatory responses with recruitment of large numbers of leukocytes, particularly T lymphocytes and ...
Asensio, Valerie C., Campbell, lain L.
openaire   +2 more sources

Differential In Vitro Infection of Neural Cells by Astroviruses

mBio, 2019
Recent advances in unbiased pathogen discovery have implicated astroviruses as pathogens of the central nervous system (CNS) of mammals, including humans.
Andrew B. Janowski, Robyn S. Klein, David Wang   +2 more
doaj   +1 more source

Human Brain Organoids as Models for Central Nervous System Viral Infection

, 2022
Pathogenesis of viral infections of the central nervous system (CNS) is poorly understood, and this is partly due to the limitations of currently used preclinical models. Brain organoid models can overcome some of these limitations, as they are generated
Josse A. Depla, Lance A. Mulder, Sridhar, Adithya, Wolthers, Katja C., Pajkrt, Dasja, Melvin M. Evers, Depla, Josse A., Wartel, Morgane, Evers, Melvin M., Renata Vieira de Sá, Adithya Sridhar, de Sá, Renata Vieira, Katja C. Wolthers, Morgane Wartel, Dasja Pajkrt, Mulder, Lance A.   +15 more
core   +1 more source

Human Parvovirus 4 as Potential Cause of Encephalitis in Children, India

, 2011
To investigate whether uncharacterized infectious agents were associated with neurologic disease, we analyzed cerebrospinal fluid specimens from 12 children with acute central nervous system infection.
Vasanthapuram, R., Laura Benjamin, Lewthwaite, P., Ravi Vasanthapuram, Vasanthapuram, Ravi, Colin P. Sharp, Simmonds, Peter, David Wang, Peter Simmonds, Lewthwaite, Penny, Zhao, G., Tom Solomon, Guoyan Zhao, Sharp, C., Benjamin, Laura A, Sharp, Colin, Solomon, T., Benjamin, L.A., Zhao, Guoyan, Penny Lewthwaite, Wang, D., Laura A. Benjamin, Wang, David, Simmonds, P., Solomon, Tom   +24 more
core   +1 more source

Increased Hospitalizations for Neuropathies as Indicators of Zika Virus Infection, according to Health Information System Data, Brazil

Emerging Infectious Diseases, 2016
Evidence is increasing that Zika virus can cause extensive damage to the central nervous system, affecting both fetuses and adults. We sought to identify traces of possible clinical manifestations of nervous system diseases among the registers of ...
Christovam Barcellos, Diego Ricardo Xavier, Ana Luiza Pavão, Cristiano Siqueira Boccolini, Maria Fatima Pina, Marcel Pedroso, Dalia Romero, Anselmo Rocha Romão   +7 more
doaj   +1 more source