Results 111 to 120 of about 18,770 (220)

Fifteen years of research on oral–facial–digital syndromes: from 1 to 16 causal genes [PDF]

, 2017
Oral–facial–digital syndromes (OFDS) gather rare genetic disorders characterised by facial, oral and digital abnormalities associated with a wide range of additional features (polycystic kidney disease, cerebral malformations and several others) to ...
Aral, B, Argente, J, Attie-Bitach, T, Baumann, C, Birnbaum, D, Blacque, OE, Bongers, E, Bruel, A-L, Burglen, L, Chevrier, V, Cormier-Daire, V, David, A, Deleuze, J-F, Desguerres, I, Dieux, A, Doray, B, Doummar, D, Duffourd, Y, Eguether, T, Faivre, L, Fargeot-Espaliat, A, Franco, B, Gaillard, D, Gigot, N, Gilbert-Dussardier, B, Giles, RH, Goldenberg, A, Goldstein, JS, Herranz-Pérez, V, Huynen, MA, Jego, L, Johnson, CA, Leroux, MR, Loget, P, Lopez, E, Morleo, M, Mégarbané, A, Nachury, MV, Panigrahi, I, Pasquier, L, Pazour, GJ, Phadke, SR, Pierquin, G, Reversade, B, Rivière, J-B, Rosnet, O, Saunier, S, St-Onge, J, Steichen-Gersdorf, E, Thauvin-Robinet, C, Thevenon, J, Wallingford, JB   +51 more
core   +3 more sources

Atypical Centrioles During Sexual Reproduction

Frontiers in Cell and Developmental Biology, 2015
Centrioles are conserved, self-replicating, microtubule-based 9-fold symmetric subcellular organelles that are essential for proper cell division and function.
Tomer eAvidor-Reiss, Atul eKhire, Emily Lillian Fishman, Kyoung Ha Jo   +3 more
doaj   +1 more source

Separase prevents genomic instability by controlling replication fork speed [PDF]

, 2016
Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development.
Cucco, Francesco, Palumbo, Elisa, Camerini, Serena, D'Alessio, Barbara, Quarantotti, Valentina, Casella, Maria Luisa, Rizzo, Ilaria Maria, Cukrov, Dubravka, Delia, Domenico, Russo, Antonella, Crescenzi, Marco, Musio, Antonio   +11 more
core   +4 more sources

9-fold symmetry is not essential for centriole elongation and formation of new centriole-like structures

Nature Communications
As daughter centrioles assemble during G2, they recruit conserved Ana3/RTTN followed by its partner Rcd4/PPP1R35. Together, this contributes to the subsequent recruitment of Ana1/CEP295, required for the centriole’s conversion to a centrosome.
Pallavi Panda, Mark S. Ladinsky, David M. Glover   +2 more
doaj   +1 more source

Male gametogenesis without centrioles

Developmental Biology, 2011
The orientation of the mitotic spindle plays a central role in specifying stem cell-renewal by enabling interaction of the daughter cells with external cues: the daughter cell closest to the hub region is instructed to self-renew, whereas the distal one starts to differentiate.
Riparbelli, Maria Giovanna, Callaini, Giuliano   +1 more
openaire   +3 more sources

CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

Cell Reports, 2018
Summary: The centrosome is the main microtubule-organizing center in animal cells and comprises a mother and daughter centriole surrounded by pericentriolar material.
Maren Mönnich, Louise Borgeskov, Loretta Breslin, Lis Jakobsen, Michaela Rogowski, Canan Doganli, Jacob M. Schrøder, Johanne B. Mogensen, Louise Blinkenkjær, Lea M. Harder, Emma Lundberg, Stefan Geimer, Søren T. Christensen, Jens S. Andersen, Lars A. Larsen, Lotte B. Pedersen   +15 more
doaj   +1 more source

Ultrastructures of spermatozoon tail in rice water weevil, Lissorhoptrus oryzophilus Kuschel (Coleoptera, Curculionidae)

浙江大学学报. 农业与生命科学版, 2008
Ultrastructures of spermatozoon tail in the rice water weevil, Lissorhoptrus oryzophilus, were observed via transmission electron microscopy at selected sperm developmental stages with the aim at clarifying spermiogenesis in this weevil.
HE Yan, JI Xiang-hua, JIANG Ming-xing, CHENG Jia-an   +3 more
doaj   +1 more source

Centrioles take center stage [PDF]

Current Biology, 2001
Centrioles are among the most beautiful and mysterious of all cell organelles. Although the ultrastructure of centrioles has been studied in great detail ever since the advent of electron microscopy, these studies raised as many questions as they answered, and for a long time both the function and mode of duplication of centrioles remained ...
openaire   +2 more sources

mTOR controls ependymal cell differentiation by targeting the alternative cell cycle and centrosomal proteins

EMBO Reports
Ependymal cells are multiciliated glial cells lining the ventricles of the mammalian brain. Their differentiation from progenitor cells involves cell enlargement and progresses through centriole amplification phases and ciliogenesis.
Alexia Bankolé, Ayush Srivastava, Asm Shihavuddin, Khaled Tighanimine, Marion Faucourt, Vonda Koka, Solene Weill, Ivan Nemazanyy, Alissa J Nelson, Matthew P Stokes, Nathalie Delgehyr, Auguste Genovesio, Alice Meunier, Stefano Fumagalli, Mario Pende, Nathalie Spassky   +15 more
doaj   +1 more source

Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole

Nature Communications, 2016
Newly formed centrioles mature into functional mother centrioles. Here the authors show that the scaffolding protein Cep295 is recruited to the procentriole assembly site and assists daughter centriole assembly and daughter-to-mother centriole conversion.
Yuki Tsuchiya, Satoko Yoshiba, Akshari Gupta, Koki Watanabe, Daiju Kitagawa   +4 more
doaj   +1 more source