Results 121 to 130 of about 18,948 (224)

The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression

open access: yesMolecular Cancer, 2011
Background Infection with high-risk human papillomaviruses (HPVs) such as HPV-16 is intimately associated with squamous cell carcinomas (SCCs) of the anogenital tract and a subset of oropharyngeal carcinomas.
Duensing Stefan   +2 more
doaj   +1 more source

Centrioles take center stage [PDF]

open access: yesCurrent Biology, 2001
Centrioles are among the most beautiful and mysterious of all cell organelles. Although the ultrastructure of centrioles has been studied in great detail ever since the advent of electron microscopy, these studies raised as many questions as they answered, and for a long time both the function and mode of duplication of centrioles remained ...
openaire   +2 more sources

mTOR controls ependymal cell differentiation by targeting the alternative cell cycle and centrosomal proteins

open access: yesEMBO Reports
Ependymal cells are multiciliated glial cells lining the ventricles of the mammalian brain. Their differentiation from progenitor cells involves cell enlargement and progresses through centriole amplification phases and ciliogenesis.
Alexia Bankolé   +15 more
doaj   +1 more source

Ultrastructures of spermatozoon tail in rice water weevil, Lissorhoptrus oryzophilus Kuschel (Coleoptera, Curculionidae)

open access: yes浙江大学学报. 农业与生命科学版, 2008
Ultrastructures of spermatozoon tail in the rice water weevil, Lissorhoptrus oryzophilus, were observed via transmission electron microscopy at selected sperm developmental stages with the aim at clarifying spermiogenesis in this weevil.
HE Yan   +3 more
doaj   +1 more source

A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family [PDF]

open access: yes, 2017
Asymmetric cell division is essential for normal human brain development. Mutations in several genes encoding centrosomal proteins that participate in accurate cell division have been reported to cause autosomal recessive primary microcephaly (MCPH).
Altmüller, Janine   +16 more
core  

Laser Microirradiation of Chinese Hamster Cells at Wavelength 365 nm [PDF]

open access: yes, 1981
Cells of a V79 subline of the Chinese hamster were microirradiated at wavelength 365 nm in the presence of the psoralen derivative, trioxsalen. Microirradiation was accomplished by a pulsed argon laser microbeam either in anaphase or in interphase 3 hr ...
Berns, Michael W.   +3 more
core  

Geometry of Morphogenesis

open access: yes, 2014
We introduce a formalism for the geometry of eukaryotic cells and organisms.Cells are taken to be star-convex with good biological reason. This allows for a convenient description of their extent in space as well as all manner of cell surface gradients ...
Morozova, Nadya, Penner, Robert
core   +1 more source

Positioning centrioles and centrosomes

open access: yesJournal of Cell Biology
Centrosomes are the primary microtubule organizer in eukaryotic cells. In addition to shaping the intracellular microtubule network and the mitotic spindle, centrosomes are responsible for positioning cilia and flagella. To fulfill these diverse functions, centrosomes must be properly located within cells, which requires that they undergo intracellular
Matthew R. Hannaford, Nasser M. Rusan
openaire   +2 more sources

The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles [PDF]

open access: yes, 2002
The centrosomal protein C-Nap1 is thought to play an important role in centrosome cohesion during interphase of the cell cycle. At the onset of mitosis, when centrosomes separate for bipolar spindle formation, C-Nap1 dissociates from centrosomes. Here we
Hacker, Ulrike   +3 more
core  

Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity

open access: yesNature Communications
Centrioles define centrosome structure and function. Deregulation of centriole numbers can cause developmental defects and cancer. The p53 tumor suppressor limits the growth of cells lacking or harboring additional centrosomes and can be engaged by the ...
Marina A. Schapfl   +8 more
doaj   +1 more source

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