Results 111 to 120 of about 18,948 (224)

Separase prevents genomic instability by controlling replication fork speed [PDF]

open access: yes, 2016
Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development.
Cucco, Francesco   +11 more
core   +4 more sources

The mother centriole plays an instructive role in defining cell geometry.

open access: yesPLoS Biology, 2007
Centriole positioning is a key step in establishment and propagation of cell geometry, but the mechanism of this positioning is unknown. The ability of pre-existing centrioles to induce formation of new centrioles at a defined angle relative to ...
Jessica L Feldman   +2 more
doaj   +1 more source

Production of Basal Bodies in bulk for dense multicilia formation [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Centriole number is normally under tight control and is directly linked to ciliogenesis. In cells that use centrosomes as mitotic spindle poles, one pre-existing mother centriole is allowed to duplicate only one daughter centriole per cell cycle.
Xiumin Yan, Huijie Zhao, Xueliang Zhu
doaj   +1 more source

The importance of a single primary cilium [PDF]

open access: yes, 2013
The centrosome is the main microtubule-organizing center in animal cells, and helps to influence the morphology of the microtubule cytoskeleton in interphase and mitosis. The centrosome also templates the assembly of the primary cilium, and together they
Mahjoub, Moe R
core   +2 more sources

Atypical Centrioles During Sexual Reproduction

open access: yesFrontiers in Cell and Developmental Biology, 2015
Centrioles are conserved, self-replicating, microtubule-based 9-fold symmetric subcellular organelles that are essential for proper cell division and function.
Tomer eAvidor-Reiss   +3 more
doaj   +1 more source

Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly

open access: yeseLife, 2013
Centrioles organise centrosomes and template cilia and flagella. Several centriole and centrosome proteins have been linked to microcephaly (MCPH), a neuro-developmental disease associated with small brain size. CPAP (MCPH6) and STIL (MCPH7) are required
Matthew A Cottee   +9 more
doaj   +1 more source

Sperm morphology in five species of cicadettine cicadas (Hemiptera: Cicadomorpha: Cicadidae) [PDF]

open access: yes, 2006
Mature spermatozoa from five species of cicadas of the subfamily Cicadettinae (Quintilia wealei, Melampsalta leucoptera, Stagira simplex, Xosopsaltria thunbergi and Monomatapa matoposa) were examined by light and electron microscopy.
Chawanji, A S   +2 more
core   +2 more sources

Male gametogenesis without centrioles

open access: yesDevelopmental Biology, 2011
The orientation of the mitotic spindle plays a central role in specifying stem cell-renewal by enabling interaction of the daughter cells with external cues: the daughter cell closest to the hub region is instructed to self-renew, whereas the distal one starts to differentiate.
Riparbelli, Maria Giovanna   +1 more
openaire   +3 more sources

9-fold symmetry is not essential for centriole elongation and formation of new centriole-like structures

open access: yesNature Communications
As daughter centrioles assemble during G2, they recruit conserved Ana3/RTTN followed by its partner Rcd4/PPP1R35. Together, this contributes to the subsequent recruitment of Ana1/CEP295, required for the centriole’s conversion to a centrosome.
Pallavi Panda   +2 more
doaj   +1 more source

CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

open access: yesCell Reports, 2018
Summary: The centrosome is the main microtubule-organizing center in animal cells and comprises a mother and daughter centriole surrounded by pericentriolar material.
Maren Mönnich   +15 more
doaj   +1 more source

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