Shape And Copy Number Of Centriole Duplication
, 2016 Centrioles are microtubule-based, 9-fold symmetrical cylinder-like structures that duplicate exactly once per cell cycle. The 9-fold symmetry is defined by a geometric scaffold known as the cartwheel, upon which all centrioles are formed.
Kim, Minhee
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Positioning centrioles and centrosomes
Journal of Cell BiologyCentrosomes are the primary microtubule organizer in eukaryotic cells. In addition to shaping the intracellular microtubule network and the mitotic spindle, centrosomes are responsible for positioning cilia and flagella. To fulfill these diverse functions, centrosomes must be properly located within cells, which requires that they undergo intracellular
Matthew R. Hannaford, Nasser M. Rusan
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The physiology of the reproductive cycle of the powan of Loch Lomond, Coregonus lavaretus (L) (Euteleostei, Salmonidae) in relation to the deposition and mobilization of storage products [PDF]
, 2012 There have been numerous studies in which the reproductive cycles of teleosts have been correlated with either environmental cycles or associated physiological cycles, or both. Such correlation is seldom accurately achieved; usually because
Rashid, Karim Hamid
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Molecular Architecture of the Centriole Proteome [PDF]
, 2009 Centrioles are intriguing cylindrical organelles composed of triplet microtubules. We used mass-spectrometry based MudPIT (multidimensional protein identification technology) to identify the protein composition of centrioles isolated from the green alga ...
Keller, Lani C.
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CDK5RAP2 Regulates Centriole Licensing to Restrict Centriole Duplication in Mice
, 2009 Cells division is a highly coordinated series of events that must occur with extreme precision. Defects during segregation of genetic material (DNA) can have adverse effects on the health of the cell, surrounding tissue, organ, and the organism as a ...
Barrera, Jose Anselmo
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Centriole biogenesis: a tale of two pathways
, 2011 Two recent studies in Drosophila demonstrate that overexpression of proteins required for centriole duplication can not only induce centriole over-duplication in cells containing centrioles, but can also drive de novo centriole assembly in unfertilized ...
Khodjakov, Alexey +2 more
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Plk4-induced Centriole Biogenesis in Human Cells [PDF]
, 2008 Kleylein-Sohn, Julia
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Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity
Nature CommunicationsCentrioles define centrosome structure and function. Deregulation of centriole numbers can cause developmental defects and cancer. The p53 tumor suppressor limits the growth of cells lacking or harboring additional centrosomes and can be engaged by the ...
Marina A. Schapfl +8 more
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Human CPAP and CP110 in centriole elongation and ciliogenesis [PDF]
, 2010 Schmidt, Thorsten
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Centrobin serves as a safeguard to guide timely centriole maturation during the cell cycle
Scientific ReportsCentrioles assemble and segregate in link to the cell cycle. Daughter centrioles assemble at S phase, and become young mother centrioles after M phase. Since distal appendages (DAs) are installed to young mother centrioles at the second G2/M transition ...
Dohyong Lee +6 more
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