Results 121 to 130 of about 20,027 (280)

Centriole maturation to motherhood [PDF]

Nature Reviews Molecular Cell Biology, 2015
Cep135, Ana1 (Cep295) and Asterless (Cep152) are sequentially recruited to daughter centrioles to enable their maturation into duplication-competent mother centrioles.
openaire   +3 more sources

9-fold symmetry is not essential for centriole elongation and formation of new centriole-like structures

Nature Communications
As daughter centrioles assemble during G2, they recruit conserved Ana3/RTTN followed by its partner Rcd4/PPP1R35. Together, this contributes to the subsequent recruitment of Ana1/CEP295, required for the centriole’s conversion to a centrosome.
Pallavi Panda, Mark S. Ladinsky, David M. Glover   +2 more
doaj   +1 more source

CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

Cell Reports, 2018
Summary: The centrosome is the main microtubule-organizing center in animal cells and comprises a mother and daughter centriole surrounded by pericentriolar material.
Maren Mönnich, Louise Borgeskov, Loretta Breslin, Lis Jakobsen, Michaela Rogowski, Canan Doganli, Jacob M. Schrøder, Johanne B. Mogensen, Louise Blinkenkjær, Lea M. Harder, Emma Lundberg, Stefan Geimer, Søren T. Christensen, Jens S. Andersen, Lars A. Larsen, Lotte B. Pedersen   +15 more
doaj   +1 more source

Role for polo-like kinase 4 in mediation of cytokinesis. [PDF]

, 2019
The mitotic protein polo-like kinase 4 (PLK4) plays a critical role in centrosome duplication for cell division. By using immunofluorescence, we confirm that PLK4 is localized to centrosomes.
Brugge, Joan S, Davenport, Simon, Guzman, Roberta, Mak, Tak W, Nolan, Garry P, O'Brien, Neil, Palazzolo, Michael, Press, Michael F, Slamon, Dennis J, Xie, Bin, Zhou, Yu   +10 more
core  

Fifteen years of research on oral–facial–digital syndromes: from 1 to 16 causal genes [PDF]

, 2017
Oral–facial–digital syndromes (OFDS) gather rare genetic disorders characterised by facial, oral and digital abnormalities associated with a wide range of additional features (polycystic kidney disease, cerebral malformations and several others) to ...
Aral, B, Argente, J, Attie-Bitach, T, Baumann, C, Birnbaum, D, Blacque, OE, Bongers, E, Bruel, A-L, Burglen, L, Chevrier, V, Cormier-Daire, V, David, A, Deleuze, J-F, Desguerres, I, Dieux, A, Doray, B, Doummar, D, Duffourd, Y, Eguether, T, Faivre, L, Fargeot-Espaliat, A, Franco, B, Gaillard, D, Gigot, N, Gilbert-Dussardier, B, Giles, RH, Goldenberg, A, Goldstein, JS, Herranz-Pérez, V, Huynen, MA, Jego, L, Johnson, CA, Leroux, MR, Loget, P, Lopez, E, Morleo, M, Mégarbané, A, Nachury, MV, Panigrahi, I, Pasquier, L, Pazour, GJ, Phadke, SR, Pierquin, G, Reversade, B, Rivière, J-B, Rosnet, O, Saunier, S, St-Onge, J, Steichen-Gersdorf, E, Thauvin-Robinet, C, Thevenon, J, Wallingford, JB   +51 more
core   +2 more sources

Embryonic Development of Caenorhabditis elegans Sense Organs

Journal of Comparative Neurology, Volume 533, Issue 9, September 2025.
A high‐resolution electron microscopy dataset of a mid‐morphogenesis (comma stage) C. elegans embryo was used to reconstruct developmental intermediates as sensory neurons and their glial partners assemble into sense organs. ABSTRACT Caenorhabditis elegans sense organs provide a powerful model for understanding how different cell types interact to ...
Leland R. Wexler, Irina Kolotuev, Maxwell G. Heiman   +2 more
wiley   +1 more source

Assembly and mother centriole recruitment of IFT-B subcomplexes to form IFT-B holocomplex

Cell Structure and Function
For the biogenesis and maintenance of cilia, bidirectional protein trafficking within cilia is crucial, and is conducted by intraflagellar transport (IFT) trains containing the IFT-A and IFT-B complexes that are powered by dynein-2 and kinesin-II motors.
Koshi Tasaki, Yohei Katoh, Hye-Won Shin, Kazuhisa Nakayama   +3 more
doaj   +1 more source

The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression

Molecular Cancer, 2011
Background Infection with high-risk human papillomaviruses (HPVs) such as HPV-16 is intimately associated with squamous cell carcinomas (SCCs) of the anogenital tract and a subset of oropharyngeal carcinomas.
Duensing Stefan, Treat Benjamin, Korzeniewski Nina   +2 more
doaj   +1 more source

The basal bodies of Chlamydomonas reinhardtii [PDF]

, 2016
The unicellular green alga, Chlamydomonas reinhardtii, is a biflagellated cell that can swim or glide. C. reinhardtii cells are amenable to genetic, biochemical, proteomic, and microscopic analysis of its basal bodies.
Dutcher, Susan, O\u27Toole, Eileen T
core   +2 more sources

The Genetics of Acne

Annals of Human Genetics, Volume 89, Issue 5, Page 333-341, September 2025.
ABSTRACT This review addresses the genetics of acne vulgaris, the most common skin disease. It is characterized by the presence of comedones (blackheads), papules, and pustules. The condition is associated with sebaceous glands in the face and chest, which produce an oily substance called sebum.
Maurice A. M. Van Steensel
wiley   +1 more source