Stretching the rules: monocentric chromosomes with multiple centromere domains. [PDF]
PLoS Genetics, 2012 The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
Pavel Neumann +8 more
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Simulation and Quantitative Analysis of Spatial Centromere Distribution Patterns [PDF]
CellsA prominent feature of eukaryotic chromosomes are centromeres, which are specialized regions of repetitive DNA required for faithful chromosome segregation during cell division.
Adib Keikhosravi +3 more
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Centromere-size reduction and chromatin state dynamics following intergenomic hybridization in cotton. [PDF]
PLoS GeneticsCentromeres are pivotal for accurate chromosome segregation, yet their regulation and evolutionary dynamics remain poorly understood. Here, we investigate centromeres of the diploid species Gossypium anomalum (Ga, B-genome) that were transferred into ...
Jinlei Han +21 more
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PBRM1 directs PBAF to pericentromeres and protects centromere integrity [PDF]
Nature CommunicationsThe specialised structure of the centromere is critical for effective chromosome segregation, but its repetitive nature makes it vulnerable to rearrangements.
Karen A. Lane +12 more
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Only the Rye Derived Part of the 1BL/1RS Hybrid Centromere Incorporates CENH3 of Wheat
Frontiers in Plant Science, 2021 The precise assembly of the kinetochore complex at the centromere is epigenetically determined by substituting histone H3 with the centromere-specific histone H3 variant CENH3 in centromeric nucleosomes.
Raheleh Karimi-Ashtiyani +3 more
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The cotton centromere contains a Ty3-gypsy-like LTR retroelement. [PDF]
PLoS ONE, 2012 The centromere is a repeat-rich structure essential for chromosome segregation; with the long-term aim of understanding centromere structure and function, we set out to identify cotton centromere sequences. To isolate centromere-associated sequences from
Song Luo +7 more
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A role for the CAL1-partner Modulo in centromere integrity and accurate chromosome segregation in Drosophila. [PDF]
PLoS ONE, 2012 The relationship between the nucleolus and the centromere, although documented, remains one of the most elusive aspects of centromere assembly and maintenance.
Chin-Chi Chen +3 more
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Gross Chromosomal Rearrangement at Centromeres
Biomolecules, 2023 Centromeres play essential roles in the faithful segregation of chromosomes. CENP-A, the centromere-specific histone H3 variant, and heterochromatin characterized by di- or tri-methylation of histone H3 9th lysine (H3K9) are the hallmarks of centromere ...
Ran Xu, Ziyi Pan, Takuro Nakagawa
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Centromere size scales with genome size across Eukaryotes
Scientific Reports, 2021 Previous studies on grass species suggested that the total centromere size (sum of all centromere sizes in a cell) may be determined by the genome size, possibly because stable scaling is important for proper cell division. However, it is unclear whether
Klára Plačková +2 more
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Chromosome Y centromere array deletion leads to impaired centromere function. [PDF]
PLoS ONE, 2014 The centromere is an essential chromosomal structure that is required for the faithful distribution of replicated chromosomes to daughter cells. Defects in the centromere can compromise the stability of chromosomes resulting in segregation errors.
Alison N Graham, Paul Kalitsis
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