Results 1 to 10 of about 26,260 (212)

Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations

open access: yeseLife, 2020
Although originally thought to be silent chromosomal regions, centromeres are instead actively transcribed. However, the behavior and contributions of centromere-derived RNAs have remained unclear.
Leah Bury   +5 more
doaj   +2 more sources

De Novo Centromere Formation and Centromeric Sequence Expansion in Wheat and its Wide Hybrids. [PDF]

open access: yesPLoS Genetics, 2016
Centromeres typically contain tandem repeat sequences, but centromere function does not necessarily depend on these sequences. We identified functional centromeres with significant quantitative changes in the centromeric retrotransposons of wheat (CRW ...
Xiang Guo   +7 more
doaj   +2 more sources

Centromere Structure and Function. [PDF]

open access: yesProgress in molecular and subcellular biology, 2017
The centromere is the genetic locus that specifies the site of kinetochore assembly, where the chromosome will attach to the kinetochore microtubule. The pericentromere is the physical region responsible for the geometry of bi-oriented sister kinetochores in metaphase.
K. Bloom, V. Costanzo
semanticscholar   +5 more sources

The Ins and Outs of Aurora B Inner Centromere Localization

open access: yesFrontiers in Cell and Developmental Biology, 2017
Error-free chromosome segregation is essential for the maintenance of genomic integrity during cell division. Aurora B, the enzymatic subunit of the Chromosomal Passenger Complex (CPC), plays a crucial role in this process.
Sanne Hindriksen   +2 more
doaj   +2 more sources

Only the Rye Derived Part of the 1BL/1RS Hybrid Centromere Incorporates CENH3 of Wheat

open access: yesFrontiers in Plant Science, 2021
The precise assembly of the kinetochore complex at the centromere is epigenetically determined by substituting histone H3 with the centromere-specific histone H3 variant CENH3 in centromeric nucleosomes.
Raheleh Karimi-Ashtiyani   +3 more
doaj   +1 more source

The cotton centromere contains a Ty3-gypsy-like LTR retroelement. [PDF]

open access: yesPLoS ONE, 2012
The centromere is a repeat-rich structure essential for chromosome segregation; with the long-term aim of understanding centromere structure and function, we set out to identify cotton centromere sequences. To isolate centromere-associated sequences from
Song Luo   +7 more
doaj   +1 more source

Centromeres [PDF]

open access: yesCurrent Biology, 2016
Centromeres, chromosomal regions that become physically linked to the spindle during cell division, ensure equal division of genetic material between daughter cells. They are ubiquitous and essential in eukaryotic life. In this primer, we ask the questions 'What defines a functional centromere?' and 'What do all centromeres have in common?' To address ...
Lisa E, Kursel, Harmit S, Malik
openaire   +2 more sources

A role for the CAL1-partner Modulo in centromere integrity and accurate chromosome segregation in Drosophila. [PDF]

open access: yesPLoS ONE, 2012
The relationship between the nucleolus and the centromere, although documented, remains one of the most elusive aspects of centromere assembly and maintenance.
Chin-Chi Chen   +3 more
doaj   +1 more source

Gross Chromosomal Rearrangement at Centromeres

open access: yesBiomolecules, 2023
Centromeres play essential roles in the faithful segregation of chromosomes. CENP-A, the centromere-specific histone H3 variant, and heterochromatin characterized by di- or tri-methylation of histone H3 9th lysine (H3K9) are the hallmarks of centromere ...
Ran Xu, Ziyi Pan, Takuro Nakagawa
doaj   +1 more source

Centromere Repositioning [PDF]

open access: yesGenome Research, 1999
Primate pericentromeric regions recently have been shown to exhibit extraordinary evolutionary plasticity. In this paper we report an additional peculiar feature of these regions that we discovered while analyzing, by FISH, the evolutionary conservation of primate phylogenetic chromosome IX.
Montefalcone G   +3 more
openaire   +2 more sources

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