De Novo Centromere Formation and Centromeric Sequence Expansion in Wheat and its Wide Hybrids. [PDF]
PLoS Genetics, 2016 Centromeres typically contain tandem repeat sequences, but centromere function does not necessarily depend on these sequences. We identified functional centromeres with significant quantitative changes in the centromeric retrotransposons of wheat (CRW ...
Xiang Guo +7 more
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Centromeres in budding yeasts are conserved in chromosomal location but not in structure. [PDF]
PLoS GeneticsThe budding yeast Saccharomyces cerevisiae has 'point' centromeres, which are much smaller and simpler than centromeres of most other eukaryotes and have a defined DNA sequence.
Conor Hession +3 more
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Kinetochore mutations and histone phosphorylation pattern changes accompany holo- and macro-monocentromere evolution [PDF]
Nature CommunicationsCentromeres are essential for kinetochore assembly and spindle attachment. While chromosomes of most species are monocentric with a single centromere, a minority exhibit holocentricity, with a centromere along the chromatid length.
Yi-Tzu Kuo +12 more
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Anti-centromere antibody positivity with coexisting idiopathic portal hypertension and primary biliary cholangitis progressing to limited cutaneous systemic sclerosis: a case report [PDF]
Journal of Medical Case ReportsBackground Anti-centromere antibodies are autoantibodies that selectively bind to the centromere region of chromosomes. Studies have indicated that anti-centromere antibodies can induce microvascular alterations and tissue remodeling, ultimately leading ...
Yuya Ando +11 more
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ZSCAN4 functions as a safeguard to maintain centromere integrity during oocyte meiosis [PDF]
Genome BiologyBackground Centromeres play a vital role in ensuring accurate chromosome segregation during meiosis by serving as the foundation for kinetochore assembly and microtubule attachment.
Da Yi Choi +3 more
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Only the Rye Derived Part of the 1BL/1RS Hybrid Centromere Incorporates CENH3 of Wheat
Frontiers in Plant Science, 2021 The precise assembly of the kinetochore complex at the centromere is epigenetically determined by substituting histone H3 with the centromere-specific histone H3 variant CENH3 in centromeric nucleosomes.
Raheleh Karimi-Ashtiyani +3 more
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Current Biology, 2016 Centromeres, chromosomal regions that become physically linked to the spindle during cell division, ensure equal division of genetic material between daughter cells. They are ubiquitous and essential in eukaryotic life. In this primer, we ask the questions 'What defines a functional centromere?' and 'What do all centromeres have in common?' To address ...
Lisa E, Kursel, Harmit S, Malik
openaire +2 more sources
The cotton centromere contains a Ty3-gypsy-like LTR retroelement. [PDF]
PLoS ONE, 2012 The centromere is a repeat-rich structure essential for chromosome segregation; with the long-term aim of understanding centromere structure and function, we set out to identify cotton centromere sequences. To isolate centromere-associated sequences from
Song Luo +7 more
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EWSR1 maintains centromere identity
Cell Reports, 2023 Summary: The centromere is essential for ensuring high-fidelity transmission of chromosomes. CENP-A, the centromeric histone H3 variant, is thought to be the epigenetic mark of centromere identity.
Risa Kitagawa +4 more
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Variation in the CENP-A sequence association landscape across diverse inbred mouse strains
Cell Reports, 2023 Summary: Centromeres are crucial for chromosome segregation, but their underlying sequences evolve rapidly, imposing strong selection for compensatory changes in centromere-associated kinetochore proteins to assure the stability of genome transmission ...
Uma P. Arora +2 more
doaj +1 more source