Results 11 to 20 of about 87,751 (339)

Kinetochore mutations and histone phosphorylation pattern changes accompany holo- and macro-monocentromere evolution [PDF]

open access: yesNature Communications
Centromeres are essential for kinetochore assembly and spindle attachment. While chromosomes of most species are monocentric with a single centromere, a minority exhibit holocentricity, with a centromere along the chromatid length.
Yi-Tzu Kuo   +12 more
doaj   +2 more sources

Two Gap-free Reference Genomes and a Global View of the Centromere Architecture in Rice.

open access: yesMolecular Plant, 2021
Rice (Oryza sativa), a major staple throughout the world and a model system for plant genomics and breeding, was the first crop genome sequenced almost two decades ago.
Jia-Ming Song   +24 more
semanticscholar   +1 more source

Only the Rye Derived Part of the 1BL/1RS Hybrid Centromere Incorporates CENH3 of Wheat

open access: yesFrontiers in Plant Science, 2021
The precise assembly of the kinetochore complex at the centromere is epigenetically determined by substituting histone H3 with the centromere-specific histone H3 variant CENH3 in centromeric nucleosomes.
Raheleh Karimi-Ashtiyani   +3 more
doaj   +1 more source

Diverse mechanisms of centromere specification

open access: yesCurrent Biology, 2021
Summary The centromere performs a universally conserved function, to accurately partition genetic information upon cell division. Yet, centromeres are among the most rapidly evolving regions of the genome and are bound by varying assortments of ...
B. Mellone, D. Fachinetti
semanticscholar   +1 more source

The cotton centromere contains a Ty3-gypsy-like LTR retroelement. [PDF]

open access: yesPLoS ONE, 2012
The centromere is a repeat-rich structure essential for chromosome segregation; with the long-term aim of understanding centromere structure and function, we set out to identify cotton centromere sequences. To isolate centromere-associated sequences from
Song Luo   +7 more
doaj   +1 more source

Centromeres [PDF]

open access: yesCurrent Biology, 2016
Centromeres, chromosomal regions that become physically linked to the spindle during cell division, ensure equal division of genetic material between daughter cells. They are ubiquitous and essential in eukaryotic life. In this primer, we ask the questions 'What defines a functional centromere?' and 'What do all centromeres have in common?' To address ...
Lisa E, Kursel, Harmit S, Malik
openaire   +2 more sources

A role for the CAL1-partner Modulo in centromere integrity and accurate chromosome segregation in Drosophila. [PDF]

open access: yesPLoS ONE, 2012
The relationship between the nucleolus and the centromere, although documented, remains one of the most elusive aspects of centromere assembly and maintenance.
Chin-Chi Chen   +3 more
doaj   +1 more source

Variation in the CENP-A sequence association landscape across diverse inbred mouse strains

open access: yesCell Reports, 2023
Summary: Centromeres are crucial for chromosome segregation, but their underlying sequences evolve rapidly, imposing strong selection for compensatory changes in centromere-associated kinetochore proteins to assure the stability of genome transmission ...
Uma P. Arora   +2 more
doaj   +1 more source

Gross Chromosomal Rearrangement at Centromeres

open access: yesBiomolecules, 2023
Centromeres play essential roles in the faithful segregation of chromosomes. CENP-A, the centromere-specific histone H3 variant, and heterochromatin characterized by di- or tri-methylation of histone H3 9th lysine (H3K9) are the hallmarks of centromere ...
Ran Xu, Ziyi Pan, Takuro Nakagawa
doaj   +1 more source

What makes a centromere?

open access: yesExperimental Cell Research, 2020
Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and meiosis.
P. Talbert, S. Henikoff
semanticscholar   +1 more source

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