Results 11 to 20 of about 92,899 (342)
Stretching the rules: monocentric chromosomes with multiple centromere domains. [PDF]
PLoS Genetics, 2012 The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
Pavel Neumann +8 more
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The cotton centromere contains a Ty3-gypsy-like LTR retroelement. [PDF]
PLoS ONE, 2012 The centromere is a repeat-rich structure essential for chromosome segregation; with the long-term aim of understanding centromere structure and function, we set out to identify cotton centromere sequences. To isolate centromere-associated sequences from
Song Luo +7 more
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EWSR1 maintains centromere identity
Cell Reports, 2023 Summary: The centromere is essential for ensuring high-fidelity transmission of chromosomes. CENP-A, the centromeric histone H3 variant, is thought to be the epigenetic mark of centromere identity.
Risa Kitagawa +4 more
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Chromosome Y centromere array deletion leads to impaired centromere function. [PDF]
PLoS ONE, 2014 The centromere is an essential chromosomal structure that is required for the faithful distribution of replicated chromosomes to daughter cells. Defects in the centromere can compromise the stability of chromosomes resulting in segregation errors.
Alison N Graham, Paul Kalitsis
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Centromere domain organization and histone modifications [PDF]
Brazilian Journal of Medical and Biological Research, 2002 Centromere function requires the proper coordination of several subfunctions, such as kinetochore assembly, sister chromatid cohesion, binding of kinetochore microtubules, orientation of sister kinetochores to opposite spindle poles, and their movement ...
P. Bjerling, K. Ekwall
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Centromere Structure and Function [PDF]
Progress in molecular and subcellular biology, 2017 The centromere is the genetic locus that specifies the site of kinetochore assembly, where the chromosome will attach to the kinetochore microtubule.
K. Bloom, Vincenzo Costanzo
semanticscholar +2 more sources
Current Biology, 2016 Centromeres, chromosomal regions that become physically linked to the spindle during cell division, ensure equal division of genetic material between daughter cells. They are ubiquitous and essential in eukaryotic life. In this primer, we ask the questions 'What defines a functional centromere?' and 'What do all centromeres have in common?' To address ...
Lisa E, Kursel, Harmit S, Malik
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A role for the CAL1-partner Modulo in centromere integrity and accurate chromosome segregation in Drosophila. [PDF]
PLoS ONE, 2012 The relationship between the nucleolus and the centromere, although documented, remains one of the most elusive aspects of centromere assembly and maintenance.
Chin-Chi Chen +3 more
doaj +1 more source
Variation in the CENP-A sequence association landscape across diverse inbred mouse strains
Cell Reports, 2023 Summary: Centromeres are crucial for chromosome segregation, but their underlying sequences evolve rapidly, imposing strong selection for compensatory changes in centromere-associated kinetochore proteins to assure the stability of genome transmission ...
Uma P. Arora +2 more
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Centromere Repositioning [PDF]
Genome Research, 1999 Primate pericentromeric regions recently have been shown to exhibit extraordinary evolutionary plasticity. In this paper we report an additional peculiar feature of these regions that we discovered while analyzing, by FISH, the evolutionary conservation of primate phylogenetic chromosome IX.
Montefalcone G +3 more
openaire +2 more sources