Results 91 to 100 of about 88,605 (330)

Comparative gene mapping in Arabidopsis lyrata chromosomes 6 and 7 and A thaliana chromosome IV: evolutionary history, rearrangements and local recombination rates [PDF]

open access: yes, 2006
We have increased the density of genetic markers on the Arabidopsis lyrata chromosomes AL6 and AL7 corresponding to the A. thaliana chromosome IV, in order to determine chromosome rearrangements between these two species, and to compare recombination ...
Charlesworth, Deborah   +4 more
core   +1 more source

Centromere Structure and Function [PDF]

open access: yes, 2017
The centromere is the genetic locus that specifies the site of kinetochore assembly, where the chromosome will attach to the kinetochore microtubule. The pericentromere is the physical region responsible for the geometry of bi-oriented sister kinetochores in metaphase.
K. Bloom, V. Costanzo
openaire   +4 more sources

The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability

open access: yesCytoskeleton, EarlyView.
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou   +6 more
wiley   +1 more source

The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo

open access: yeseLife, 2014
In budding yeast, a single cenH3 (Cse4) nucleosome occupies the ∼120-bp functional centromere, however conflicting structural models for the particle have been proposed. To resolve this controversy, we have applied H4S47C-anchored cleavage mapping, which
Steven Henikoff   +8 more
doaj   +1 more source

Esperanto for histones : CENP-A, not CenH3, is the centromeric histone H3 variant [PDF]

open access: yes, 2013
The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease.
A. D. McAinsh   +72 more
core   +8 more sources

A PSHaver for Centromeric Histones [PDF]

open access: yesMolecular Cell, 2010
In this issue of Molecular Cell, Hewawasam et al. (2010) and Ranjitkar et al. (2010) identify and characterize Psh1, an E3 ubiquitin ligase that specifically targets the centromeric histone Cse4 in budding yeast and limits its misincorporation at noncentromeric regions.
H. Diego Folco, Arshad Desai
openaire   +3 more sources

Interaction Between Actin and Microtubules During Plant Development

open access: yesCytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu   +3 more
wiley   +1 more source

A time out for CENP-A

open access: yesMolecular & Cellular Oncology, 2017
Proper chromosome segregation relies on a functional centromere–kinetochore interface. We showed that chromatin containing CENtromere Protein A (CENP-A) is essential for centromere assembly, but dispensable for chromosome segregation in the presence of ...
S. Hoffmann, D. Fachinetti
doaj   +1 more source

DNA content of a functioning chicken kinetochore [PDF]

open access: yes, 2014
© The Author(s) 2014. In order to understand the three-dimensional structure of the functional kinetochore in vertebrates, we require a complete list and stoichiometry for the protein components of the kinetochore, which can be provided by genetic and ...
A Alonso   +39 more
core   +3 more sources

Centromere Emergence in Evolution [PDF]

open access: yesGenome Research, 2001
Evolutionary centromere repositioning is a paradox we have recently discovered while studying the conservation of the phylogenetic chromosome IX in primates. Two explanations were proposed: a conservative hypothesis assuming sequential pericentric inversions, and a more challenging assumption involving centromere emergence during evolution. The complex
VENTURA, MARIO   +2 more
openaire   +4 more sources

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