Results 101 to 110 of about 118,231 (380)
Arthritis Care &Research, Accepted Article.Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histological markers of skin fibrosis has not been reported. We evaluated the US‐based skin assessments for their face validity (differentiation between involved SSc and ...
Ruhani Desai +12 more
wiley +1 more source
Centromere mechanical maturation during mammalian cell mitosis
Nature Communications, 2019 During mitosis, tension at the centromere occurs from the spindle but the role of centromere mechanics in controlling metaphase tension is poorly understood.
Lauren A. Harasymiw +4 more
doaj +1 more source
Cell Reports, 2013 The centromere of many eukaryotes contains highly repetitive sequences marked by methylation of histone H3K9 by Clr4KMT1. This recruits multiple heterochromatin proteins, including Swi6 and Chp1, to form a rigid centromere and ensure accurate chromosome ...
Pao-Chen Li +5 more
doaj +1 more source
Centromere Identity and the Regulation of Chromosome Segregation
Frontiers in Cell and Developmental Biology, 2022 Eukaryotes segregate their chromosomes during mitosis and meiosis by attaching chromosomes to the microtubules of the spindle so that they can be distributed into daughter cells.
Kousik Sundararajan, Aaron F. Straight
doaj +1 more source
Genome biology, 2004 The complete sequence of rice centromere 8 reveals a small amount of centromere-specific satellite sequence in blocks interrupted by retrotransposons and other repetitive DNA, in an arrangement that is strikingly similar in overall size and content to other centromeres of multicellular eukaryotes.
James Theuri +2 more
openaire +3 more sources
A New Histone at the Centromere? [PDF]
Cell, 2012 The centromere is a classic system to study epigenetic specification, and most research has focused on a specialized histone variant, CENP-A, that is required for kinetochore assembly. Now Nishino et al. reveal a new level of complexity for centromeric chromatin, by showing that the kinetochore complex CENP-T-W-S-X shares structural and functional ...
P. Todd Stukenberg, Daniel R. Foltz
openaire +3 more sources
Chromosomal diversification and karyotype evolution of diploids in the cytologically diverse genus Prospero (Hyacinthaceae) [PDF]
, 2013 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Andrew R Leitch +7 more
core +2 more sources
Advanced Science, EarlyView.Genes associated with endometriosis risk are highly expressed in M2 macrophages, particularly ligands IL1A and IL1B. Endometrial‐type epithelium and stroma are likely recipients of these ligands. While IL1B treatment disturbs epithelial organization, blockage of the signaling results in a dose‐dependent decrease in spontanesous and evoked pain, reduces
Soledad Ochoa +15 more
wiley +1 more source
FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability
Frontiers in Cell and Developmental Biology, 2022 Alterations in the gene encoding the E3 ubiquitin ligase substrate receptor FBXO38 have been associated with several diseases, including early-onset motor neuronopathy.
Nikol Dibus +2 more
doaj +1 more source
The Ins and Outs of Aurora B Inner Centromere Localization
Front. Cell Dev. Biol., 2017 Error-free chromosome segregation is essential for the maintenance of genomic integrity during cell division. Aurora B, the enzymatic subunit of the Chromosomal Passenger Complex (CPC), plays a crucial role in this process.
Sanne Hindriksen, S. Lens, M. Hadders
semanticscholar +1 more source