Results 111 to 120 of about 51,411 (295)
Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
International Journal of Cancer, EarlyView.Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert +3 more
wiley +1 more source
CYTOLOGICAL IDENTIFICATION OF THE CHROMOSOMES INVOLVED IN SEARLE'S TRANSLOCATION AND THE LOCATION OF THE CENTROMERE IN THE X CHROMOSOME OF THE MOUSE [PDF]
, 1972 Eva M. Eicher +2 more
openalex +1 more source
iLABMED, EarlyView.Extrachromosomal circular DNA (eccDNA) has quite recently turned out to be a cardinal component in cardiovascular diseases (CVD), governing the gene expression and mechanisms of disease causation. Studies indicated an upregulation of eccDNA in pulmonary arterial hypertension (PAH), which makes it strikingly potential as a sensitive and specific ...
Saim Mahmood Khan +6 more
wiley +1 more source
A new method of detecting centromere linkage in homothallic yeast [PDF]
, 1974 A. P. James
openalex +1 more source
Performance Evaluation of a New HRD Assay (HRDsig) in Ovarian Carcinomas in Australia
Journal of Clinical Laboratory Analysis, EarlyView.In this study we have evaluated the performance of a new HRD assay (HRDsig) against two accredited HRD assays, as well as against commercial controls and inter‐laboratory comparison samples. HRDsig has demonstrated a high concordance rate for determining HRD status in ovarian carcinomas.
Pranav Dorwal +11 more
wiley +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
PROTEOMICS, EarlyView.ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Analysis of centromere co-orientation in intervarietal hybrids of common wheat (Triticum aestivum L.), by means of C-banding [PDF]
, 1985 A. Fominaya, N. Jouve
openalex +1 more source
Rheumatology &Autoimmunity, EarlyView.The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao +6 more
wiley +1 more source
Distribution of kinetochore (centromere) antigen in mammalian cell nuclei. [PDF]
, 1981 Y Möroi +3 more
openalex +1 more source