Results 111 to 120 of about 55,531 (223)

Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao, Yuan Zong, Tao Wang, Jianan Li, Zengrong Ye, Famei Zhang, Guoying Zhou   +6 more
wiley   +1 more source

A Near Telomere‐to‐Telomere Genome of Belamcanda chinensis Provides Insights Into Genome Evolution and the Biosynthesis of Characteristic Isoflavones

Plant Biotechnology Journal, EarlyView.
ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Yuan‐Yuan Wang, Bi‐Huan Chen, Gui‐Sheng Xiang, Yi‐Na Wang, Run Yang, Xiao‐Bo Li, Shi‐Yan Yuan, Yu‐Cheng Zhao, Guang‐Hui Zhang, Min‐Jian Qin, Sheng‐Chao Yang   +10 more
wiley   +1 more source

A Natural LTR Retrotransposon Insertion in the Promoter of GhNAC140‐Dt Boosts Cotton Lint Yield

Plant Biotechnology Journal, EarlyView.
ABSTRACT Transposable elements (TEs) are fundamental drivers of crop evolution and domestication. Whereas the underlying mechanisms of TE‐mediated gene activation remain poorly understood. Lint percentage is an important yield component in cotton. Here, we report a retrotransposon insertion in the promoter of GhNAC140‐Dt, a secondary wall NAC encoding ...
Yujia Yu, Xiaoguang Shang, Haitang Wang, Lijie Zhu, Xu Han, Qingfei He, Weixi Li, Yonglin Tan, Guozhong Zhu, Wangzhen Guo   +9 more
wiley   +1 more source

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

CTCF maintains centromere function and mitotic fidelity. [PDF]

J Cell Sci
Walsh E, Laskarzewski T, Maresca TJ, Stephens AD.   +3 more
europepmc   +1 more source

Assessing the adaptive potential of European beech populations to temperature and precipitation along a steep environmental gradient in the south‐eastern Carpathians

Plant Biology, EarlyView.
This study focuses on the identification of candidate SNPs involved in local adaptation to altitude by environmental association analysis conducted on different natural European beech (Fagus sylvatica) populations. Abstract It is necessary to assess the adaptive potential of European beech populations to climate change.
M. Tost, O. Grigoriadou‐Zormpa, S. Wilhelmi, M. Müller, H. Wildhagen, A. L. Curtu, O. Gailing   +6 more
wiley   +1 more source

Optimized dicentric chromosome dose-response curves with centromere probes improve low-dose radiation biodosimetry. [PDF]

Sci Rep
Jeong MH, Choi HS, Jeong SK, Kang YR, Lee CG, Kim HJ, Kye YU, Baek JH, Park MT, Kim JS, Oh SJ, Jo WS.   +11 more
europepmc   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

RB dependent transcriptional regulation at mitotic centromeres preserves genome stability. [PDF]

Life Sci Alliance
Crowley EA, Manning AL.
europepmc   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source