Results 181 to 190 of about 26,352 (303)

Cytoduction Preserves Genetic Diversity Following Plasmid Transfer Into Pooled Yeast Libraries

Yeast, EarlyView.
Unlike transformation, cytoduction (mating without nuclear fusion) is efficient at introducing plasmids into high‐diversity libraries with minimal impact on population diversity. ABSTRACT Introducing plasmids into yeast is a critical step for many phenotypic assays and genetic engineering applications.
Han‐Ying Jhuang, Dimitra Aggeli, Gregory I. Lang   +2 more
wiley   +1 more source

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis. [PDF]

, 1987
Carol Cooke, Margarete M. S. Heck, William C. Earnshaw   +2 more
openalex   +1 more source

RepeatOBserver: Tandem Repeat Visualisation and Putative Centromere Detection

Molecular Ecology Resources, EarlyView.
ABSTRACT Tandem repeats play an important role in centromere structure, subtelomeric regions, DNA methylation, recombination and the regulation of gene activity. Analysis of their distribution in genomes offers a potential means for predicting putative centromere locations, which continues to be a challenge for genome annotation.
Cassandra Elphinstone, Rob Elphinstone, Marco Todesco, Loren H. Rieseberg   +3 more
wiley   +1 more source

Strong Signatures of Selection on Candidate Genes Underlying Core Speciation Mechanisms in Desert Tortoises

Molecular Ecology Resources, EarlyView.
ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty, Raúl Araya‐Donoso, Avery Paulsen, Avery Williams, Dale F. DeNardo, Kenro Kusumi, Greer A. Dolby   +6 more
wiley   +1 more source

A centromere’s obsession with transposons [PDF]

Nature Plants
Transposable elements frequently invade centromeres, yet their influence on centromere function has long been enigmatic. A new study reveals that epigenetic silencing of centromeric transposable elements is essential for chromosome cohesion and proper segregation during cell division.
openaire   +3 more sources

Distribution of kinetochore (centromere) antigen in mammalian cell nuclei. [PDF]

, 1981
Y Möroi, A L Hartman, Paul K. Nakane, Eng M. Tan   +3 more
openalex   +1 more source

The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex

Nature Cell Biology, 2019
Prasad D. Trivedi, F. Palomba, E. Niedzialkowska, M. Digman, E. Gratton, P. Stukenberg   +5 more
semanticscholar   +1 more source

A Guide to Screening for Autoimmune Diseases in Patients With Vulvar Lichen Sclerosus

Australasian Journal of Dermatology, EarlyView.
ABSTRACTBackgroundThe aetiology of vulvar lichen sclerosus (VLS) remains unknown. However, there is evidence that in addition to a genetic predisposition, autoimmunity contributes to the pathogenesis.ObjectivesThe objective of this study was to determine the prevalence of autoimmune disease and positive autoantibody serology in patients with VLS ...
Annabel Guttentag, Marlene Wijaya, Gayle O. Fischer, Angela Lee, Ken Liu, Rebecca Bronwyn Saunderson   +5 more
wiley   +1 more source

Recombination between two mouset-haplotypes (t^w12tfandt^Lub-1): segregation of lethal factors relative to centromere and tufted (tf) locus [PDF]

, 1983
Hubert Condamine, Jean‐Louis Guénet, François Jacob   +2 more
openalex   +1 more source

Innovative all‐in‐one exome sequencing strategy for diagnostic genetic testing in male infertility: Validation and 10‐month experience

Andrology, EarlyView.
Abstract Background Current guidelines indicate that patients with extreme oligozoospermia or azoospermia should be tested for chromosomal imbalances, azoospermia factor (AZF) deletions and/or CFTR variants. For other sperm abnormalities, no genetic diagnostics are recommended.
Manon S. Oud, Nicole de Leeuw, Dominique F. C. M. Smeets, Liliana Ramos, Godfried W. van der Heijden, Raoul G. J. Timmermans, Maartje van de Vorst, Tom Hofste, Marlies J. E. Kempers, Marijn F. Stokman, Kathleen W. M. D'Hauwers, Brigitte H. W. Faas, Dineke Westra   +12 more
wiley   +1 more source