Unveiling the Evolutionary History of European Vipers and Their Venoms From a Multi‐Omic Approach
ABSTRACT Snake genomes attract significant attention from multiple disciplines, including medicine, drug bioprospection, and evolutionary biology. However, genomic research within the Viperidae family has mostly focused on the subfamily Crotalinae, while the true vipers (Viperinae) have largely been overlooked.
Adrián Talavera+15 more
wiley +1 more source
Multiple Origins of Sex Chromosomes in Nothobranchius Killifishes
ABSTRACT Sex chromosomes have evolved repeatedly across eukaryotes. The emergence of a sex‐determining (SD) locus is expected to progressively restrict recombination, driving convergent molecular differentiation. However, evidence from taxa like teleost fishes, representing over half of vertebrate species with unmatched diversity in SD systems ...
Monika Hospodářská+19 more
wiley +1 more source
Hypogammaglobulinemia in patients affected by limited cutaneous systemic sclerosis: Case series and review of the literature. [PDF]
Danieli MG+5 more
europepmc +1 more source
Homeostatic Influence of Fig4 Outside of the Fab1‐Vac14‐Fig4 Complex in Saccharomyces cerevisiae
Disease‐related Fig4 mutants displaying impaired association with the Fab1‐Vac14‐Fig4 complex confer rapamycin tolerance in Saccharomyces cerevisiae independent of Vac14 and Fig4 catalytic function. Fig4 may thus modulate homeostasis through uncharacterized molecular interactions that lead to altered function when not bound to Vac14. ABSTRACT The lipid
Hannah E. Reeves+13 more
wiley +1 more source
Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis. [PDF]
Herklotz V+12 more
europepmc +1 more source
Dynamic patterns of repeats and retrotransposons in the centromeres of Humulus lupulus L.
Summary The centromere has a conserved function across eukaryotes; however, the associated DNA sequences exhibit remarkable diversity in both size and structure. In plants, some species possess well‐defined centromeres dominated by tandem satellite repeats and centromeric retrotransposons, while others have centromeric regions composed almost entirely ...
Lucie Horáková+13 more
wiley +1 more source
Comparative analysis of cattle (Bos taurus, 2n = 60) and river buffalo (Bubalus bubalis, 2n = 50) genome assemblies reveals two evolutionary conserved inversions and invalid centromere-telomere orientation of some autosomes. [PDF]
Pistucci R+7 more
europepmc +1 more source
Lipedema: Progress, Challenges, and the Road Ahead
ABSTRACT Introduction Lipedema is a chronic and progressive disease that predominantly affects women, characterized by a disproportionate increase in subcutaneous adipose tissue (AT), particularly in the lower limbs. It is associated with significant physical disability, chronic pain, thromboembolism, and psychosocial distress.
Vincenza Cifarelli
wiley +1 more source
Summary Leaf colour mutants are ideal germplasm resources for investigating the mechanisms of chlorophyll (Chl) synthesis, chloroplast development and photosynthesis. In this study, we obtained a yellow‐leaf mutant, designated SN288‐2. The variant presented a yellow‐leaf phenotype and halted the development of chloroplasts at the seedling stage, with ...
Fei Qi+5 more
wiley +1 more source
The effects of Non3 mutations on chromatin organization in Drosophila melanogaster. [PDF]
Yushkova AA+5 more
europepmc +1 more source