Chromosome Centromeres: Structural and Analytical Investigations with High Resolution Scanning Electron Microscopy in Combination with Focused Ion Beam Milling [PDF]
, 2009 Whole mount mitotic metaphase chromosomes of different plants and animals were investigated with high resolution field emission scanning electron microscopy (FESEM) to study the ultrastructural organization of centromeres, including metacentric ...
Schroeder-Reiter, E., Wanner, Gerhard
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Centromere domain organization and histone modifications
Brazilian Journal of Medical and Biological Research, 2002 Centromere function requires the proper coordination of several subfunctions, such as kinetochore assembly, sister chromatid cohesion, binding of kinetochore microtubules, orientation of sister kinetochores to opposite spindle poles, and their movement ...
P. Bjerling, K. Ekwall
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Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii.
PLoS Genetics, 2021 Deletion of native centromeres in the human fungal pathogen Cryptococcus deuterogattii leads to neocentromere formation. Native centromeres span truncated transposable elements, while neocentromeres do not and instead span actively expressed genes.
Klaas Schotanus +2 more
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Comparative Analysis of Tandem Repeats from Hundreds of Species Reveals Unique Insights into Centromere Evolution [PDF]
, 2012 Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied, centromeres contain megabase-scale arrays of tandem repeats.
Bradnam, Keith R. +16 more
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Centromeric transcription maintains centromeric cohesion in human cells [PDF]
Journal of Cell Biology, 2021 Centromeric transcription has been shown to play an important role in centromere functions. However, lack of approaches to specifically manipulate centromeric transcription calls into question that the proposed functions are a direct consequence of centromeric transcription.
Yujue Chen +3 more
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Temporal characterization of homology-independent centromere coupling in meiotic prophase. [PDF]
PLoS ONE, 2010 Over the past thirty years several reports of the pairing or association of non-homologous centromeres during meiotic prophase have appeared in the literature.
David Obeso, Dean S Dawson
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Fluorescence in situ hybridisation study of micronuclei in C3A cells following exposure to ELF-magnetic fields [PDF]
, 2019 Human C3A cells were exposed to extremely low frequency (50 Hz) magnetic fields (ELF-MF's) up to 500 mu T. They were subjected to the micronucleus assay using a Fluorescence In Situ Hybridization (FISH) technique with an in-house pan-centromere probe. We
Antonissen, Roel +4 more
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Phosphorylation of CENP-A on serine 7 does not control centromere function [PDF]
, 2019 CENP-A is the histone H3 variant necessary to specify the location of all eukaryotic centromeres via its CENP-A targeting domain and either one of its terminal regions.
Aslanian A. +9 more
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Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation. [PDF]
PLoS Genetics, 2018 Centromere is a specialized chromatin domain that plays a vital role in chromosome segregation. In most eukaryotes, centromere is surrounded by the epigenetically distinct heterochromatin domain. Heterochromatin has been shown to contribute to centromere
Jinpu Yang +7 more
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The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA [PDF]
, 2018 Centromeres are the chromosomal domains required to ensure faithful transmission of the genome during cell division. They have a central role in preventing aneuploidy, by orchestrating the assembly of several components required for chromosome separation.
Barra V., Fachinetti D.
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