Results 21 to 30 of about 59,497 (285)
Centromere domain organization and histone modifications
Brazilian Journal of Medical and Biological Research, 2002 Centromere function requires the proper coordination of several subfunctions, such as kinetochore assembly, sister chromatid cohesion, binding of kinetochore microtubules, orientation of sister kinetochores to opposite spindle poles, and their movement ...
P. Bjerling, K. Ekwall
doaj +1 more source
Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii.
PLoS Genetics, 2021 Deletion of native centromeres in the human fungal pathogen Cryptococcus deuterogattii leads to neocentromere formation. Native centromeres span truncated transposable elements, while neocentromeres do not and instead span actively expressed genes.
Klaas Schotanus +2 more
doaj +1 more source
Centromeric transcription maintains centromeric cohesion in human cells [PDF]
Journal of Cell Biology, 2021 Centromeric transcription has been shown to play an important role in centromere functions. However, lack of approaches to specifically manipulate centromeric transcription calls into question that the proposed functions are a direct consequence of centromeric transcription.
Yujue Chen +3 more
openaire +2 more sources
Temporal characterization of homology-independent centromere coupling in meiotic prophase. [PDF]
PLoS ONE, 2010 Over the past thirty years several reports of the pairing or association of non-homologous centromeres during meiotic prophase have appeared in the literature.
David Obeso, Dean S Dawson
doaj +1 more source
Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation. [PDF]
PLoS Genetics, 2018 Centromere is a specialized chromatin domain that plays a vital role in chromosome segregation. In most eukaryotes, centromere is surrounded by the epigenetically distinct heterochromatin domain. Heterochromatin has been shown to contribute to centromere
Jinpu Yang +7 more
doaj +1 more source
Atypical centromeres in plants – what they can tell us
Frontiers in Plant Science, 2015 The centromere, visible as the primary constriction of condensed metaphase chromosomes, is a defined chromosomal locus essential for genome stability. It mediates transient assembly of a multi-protein complex, the kinetochore, which enables interaction ...
Maria eCuacos +2 more
doaj +1 more source
Sequential assembly of centromeric proteins in male mouse meiosis. [PDF]
PLoS Genetics, 2009 The assembly of the mitotic centromere has been extensively studied in recent years, revealing the sequence and regulation of protein loading to this chromosome domain. However, few studies have analyzed centromere assembly during mammalian meiosis. This
María Teresa Parra +6 more
doaj +1 more source
Cell Reports, 2021 Summary: Functional tags are ubiquitous in cell biology, and for studies of one chromosomal locus, the centromere, tags have been remarkably useful. The centromere directs chromosome inheritance at cell division. The location of the centromere is defined
Catalina Salinas-Luypaert +6 more
doaj +1 more source
Key centromere proteins in Physcomitrella patens identified via SPIDER and IP-MS
Shenzhen Daxue xuebao. Ligong banPlant artificial chromosomes play a crucial role in synthetic biology, wherein key centromere proteins represent essential components in synthesizing these chromosomes. However, the identification of centromere proteins in plants remains limited.
LIU Xuedong +3 more
doaj +1 more source
Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase. [PDF]
PLoS Genetics, 2010 Eukaryotic centromeres are maintained at specific chromosomal sites over many generations. In the budding yeast Saccharomyces cerevisiae, centromeres are genetic elements defined by a DNA sequence that is both necessary and sufficient for function ...
Amnon Koren +5 more
doaj +1 more source