EWSR1 maintains centromere identity
Cell Reports, 2023 Summary: The centromere is essential for ensuring high-fidelity transmission of chromosomes. CENP-A, the centromeric histone H3 variant, is thought to be the epigenetic mark of centromere identity.
Risa Kitagawa +4 more
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Cenh3: An Emerging Player in Haploid Induction Technology. [PDF]
, 2016 True-breeding lines are required for the development and production of crop varieties. In a classical breeding approach these lines are obtained through inbreeding, and often 7-9 generations of inbreeding is performed to achieve the desired level of ...
Britt, Anne B, Kuppu, Sundaram
core +5 more sources
Variation in the CENP-A sequence association landscape across diverse inbred mouse strains
Cell Reports, 2023 Summary: Centromeres are crucial for chromosome segregation, but their underlying sequences evolve rapidly, imposing strong selection for compensatory changes in centromere-associated kinetochore proteins to assure the stability of genome transmission ...
Uma P. Arora +2 more
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Sequential assembly of centromeric proteins in male mouse meiosis. [PDF]
PLoS Genetics, 2009 The assembly of the mitotic centromere has been extensively studied in recent years, revealing the sequence and regulation of protein loading to this chromosome domain. However, few studies have analyzed centromere assembly during mammalian meiosis. This
María Teresa Parra +6 more
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Sex Differences in Recombination in Sticklebacks. [PDF]
, 2018 Recombination often differs markedly between males and females. Here we present the first analysis of sex-specific recombination in Gasterosteus sticklebacks. Using whole-genome sequencing of 15 crosses between G. aculeatus and G.
Cheng, Changde +6 more
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CENH3-GFP: a visual marker for gametophytic and somatic ploidy determination in Arabidopsis thaliana [PDF]
, 2016 Background: The in vivo determination of the cell-specific chromosome number provides a valuable tool in several aspects of plant research. However, current techniques to determine the endosystemic ploidy level do not allow non-destructive, cell-specific
Angenon, Geert +4 more
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Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase. [PDF]
PLoS Genetics, 2010 Eukaryotic centromeres are maintained at specific chromosomal sites over many generations. In the budding yeast Saccharomyces cerevisiae, centromeres are genetic elements defined by a DNA sequence that is both necessary and sufficient for function ...
Amnon Koren +5 more
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Holocentric Chromosomes of Luzula elegans Are Characterized by a Longitudinal Centromere Groove, Chromosome Bending, and a Terminal Nucleolus Organizer Region [PDF]
, 2011 The structure of holocentric chromosomes was analyzed in mitotic cells of Luzula elegans. Light and scanning electron microscopy observations provided evidence for the existence of a longitudinal groove along each sister chromatid.
A. Houben +53 more
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Atypical centromeres in plants – what they can tell us
Frontiers in Plant Science, 2015 The centromere, visible as the primary constriction of condensed metaphase chromosomes, is a defined chromosomal locus essential for genome stability. It mediates transient assembly of a multi-protein complex, the kinetochore, which enables interaction ...
Maria eCuacos +2 more
doaj +1 more source
Centromere plasmid: a new genetic tool for the study of Plasmodium falciparum. [PDF]
PLoS ONE, 2012 The introduction of transgenes into Plasmodium falciparum, a highly virulent human malaria parasite, has been conducted either by single crossover recombination or by using episomal plasmids.
Shiroh Iwanaga +3 more
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