Assembly of specialised chromatin at Fission Yeast Centromeres [PDF]
, 2015 Despite the conserved essential function of centromeres, centromeric DNA is not conserved between species. There is strong evidence indicating that centromeres are epigenetically regulated. Although centromeres normally assemble on preferred sequences,
Pidoux, Alison L.
core
Automatic Classification of Human Epithelial Type 2 Cell Indirect Immunofluorescence Images using Cell Pyramid Matching [PDF]
, 2014 This paper describes a novel system for automatic classification of images obtained from Anti-Nuclear Antibody (ANA) pathology tests on Human Epithelial type 2 (HEp-2) cells using the Indirect Immunofluorescence (IIF) protocol.
Hobson, Peter +5 more
core +3 more sources
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]
, 2010 Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel +2 more
core +2 more sources
HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons. [PDF]
, 2012 Major human pathologies are caused by nuclear replicative viruses establishing life-long latent infection in their host. During latency the genomes of these viruses are intimately interacting with the cell nucleus environment.
Catez, Frédéric +8 more
core +5 more sources
PLoS Genetics, 2019 Sister centromere fusion is a process unique to meiosis that promotes co-orientation of the sister kinetochores, ensuring they attach to microtubules from the same pole during metaphase I.
Lin-Ing Wang, Arunika Das, Kim S McKim
doaj +1 more source
Structure and Stability of Telocentric Chromosomes in Wheat. [PDF]
PLoS ONE, 2015 In most eukaryotes, centromeres assemble at a single location per chromosome. Naturally occurring telocentric chromosomes (telosomes) with a terminal centromere are rare but do exist.
Dal-Hoe Koo +3 more
doaj +1 more source
The Role of Human Centromeric RNA in Chromosome Stability
Frontiers in Molecular Biosciences, 2021 Chromosome instability is a hallmark of cancer and is caused by inaccurate segregation of chromosomes. One cellular structure used to avoid this fate is the kinetochore, which binds to the centromere on the chromosome.
Simon Leclerc, Katsumi Kitagawa
doaj +1 more source
Transcription of satellite DNAs in insects [PDF]
, 2011 Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic +3 more
core +1 more source
Pan-centromere reveals widespread centromere repositioning of soybean genomes
Proceedings of the National Academy of Sciences, 2023 Centromere repositioning refers to a de novo centromere formation at another chromosomal position without sequence rearrangement. This phenomenon was frequently encountered in both mammalian and plant species and has been implicated in genome evolution and speciation.
Yang Liu +11 more
openaire +2 more sources
Centromere mechanical maturation during mammalian cell mitosis
Nature Communications, 2019 During mitosis, tension at the centromere occurs from the spindle but the role of centromere mechanics in controlling metaphase tension is poorly understood.
Lauren A. Harasymiw +4 more
doaj +1 more source