Results 41 to 50 of about 88,605 (330)
Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast [PDF]
, 2012 The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To understand the process of epigenetic inheritance, or propagation of histones and histone variants, as ...
Allshire, Robin C +11 more
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SEQUENCE OF CENTROMERE SEPARATION: ROLE OF CENTROMERIC HETEROCHROMATIN [PDF]
Genetics, 1982 ABSTRACT The late metaphase-early anaphase cells from various tissues of male Mus musculus, M. poschiavinus, M. spretus, M. castaneus, female and male Bos taurus (cattle) and female Myopus schisticolor (wood lemming) were analyzed for centromeres that showed separation into two daughter centromeres and those that did not show such ...
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Conservation of centromeric histone 3 interaction partners in plants [PDF]
, 2020 The loading and maintenance of centromeric histone 3 (CENH3) at the centromere are critical processes ensuring appropriate kinetochore establishment and equivalent segregation of the homologous chromosomes during cell division.
Geelen, Danny +3 more
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Centromere Assembly and Propagation [PDF]
Cell, 2007 Centromere assembly provides a unique example of how elaborate protein structures can be assembled onto DNA, independent of sequence, and then stably propagated through numerous cell divisions. Here, we review the possible epigenetic strategies that organisms ranging from yeast to human use to assemble and propagate active centromeres.
Danesh Moazed, Corey A. Morris
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Epigenetics & Chromatin, 2018 Background The centromere is the specialized chromatin region that directs chromosome segregation. The kinetochore assembles on the centromere, attaching chromosomes to microtubules in mitosis.
Jing Zhu +2 more
doaj +1 more source
Holocentric Chromosomes Probably Do Not Prevent Centromere Drive in Cyperaceae
Frontiers in Plant Science, 2021 Centromere drive model describes an evolutionary process initiated by centromeric repeats expansion, which leads to the recruitment of excess kinetochore proteins and consequent preferential segregation of an expanded centromere to the egg during female ...
Marie Krátká +4 more
doaj +1 more source
The architecture of chicken chromosome territories changes during differentiation [PDF]
, 2004 BACKGROUND: Between cell divisions the chromatin fiber of each chromosome is restricted to a subvolume of the interphase cell nucleus called chromosome territory.
Bonifer, C. +7 more
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The CINs of the centromere [PDF]
Biochemical Society Transactions, 2013 Replication stress is a significant contributor to genome instability. Recent studies suggest that the centromere is particularly susceptible to replication stress and prone to rearrangements and genome damage, as well as chromosome loss. This effect is enhanced by loss of heterochromatin.
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A Positive Spin on the Centromere [PDF]
Journal of End-to-End-testing, 2009 The properties of centromeric nucleosomes have been the subject of considerable debate and controversy. Furuyama and Henikoff (2009) now provide surprising evidence that centromeric nucleosomes wrap DNA in an orientation that is opposite to that of canonical nucleosomes.
Karolin Luger +2 more
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PLoS Biology, 2021 Centromere protein A (CENP-A) is a histone H3 variant that defines centromeric chromatin and is essential for centromere function. In most eukaryotes, CENP-A-containing chromatin is epigenetically maintained, and centromere identity is inherited from one
Reinier F Prosée +7 more
doaj +1 more source