Results 61 to 70 of about 88,605 (330)
Advanced Science, EarlyView.This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai +9 more
wiley +1 more source
Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations
eLife, 2020 Although originally thought to be silent chromosomal regions, centromeres are instead actively transcribed. However, the behavior and contributions of centromere-derived RNAs have remained unclear.
Leah Bury +5 more
doaj +1 more source
Mechanism of 2n gametes formation and centromere mapping in citrus : S02O03 [PDF]
, 2012 Citrus triploid hybrids can be recovered by 2x X 2x hybridisations as a consequence of 2n gamete formation. Two main meiotic processes are at the origin of such gametes, the first division restitution (FDR) and the second division restitution (SDR ...
Aleza, Pablo +4 more
core
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]
, 2010 Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel +2 more
core +2 more sources
Centromere repositioning in mammals [PDF]
Heredity, 2011 The evolutionary history of chromosomes can be tracked by the comparative hybridization of large panels of bacterial artificial chromosome clones. This approach has disclosed an unprecedented phenomenon: 'centromere repositioning', that is, the movement of the centromere along the chromosome without marker order variation.
M. Rocchi +4 more
openaire +4 more sources
Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa
Advanced Science, EarlyView.Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang +13 more
wiley +1 more source
Bod1, a novel kinetochore protein required for chromosome biorientation [PDF]
, 2007 We have combined the proteomic analysis of Xenopus laevis in vitro–assembled chromosomes with RNA interference and live cell imaging in HeLa cells to identify novel factors required for proper chromosome segregation. The first of these is Bod1, a protein
Andersen, Jens S. +7 more
core +3 more sources
Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Advanced Science, EarlyView.Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska +18 more
wiley +1 more source
Structure and Stability of Telocentric Chromosomes in Wheat. [PDF]
PLoS ONE, 2015 In most eukaryotes, centromeres assemble at a single location per chromosome. Naturally occurring telocentric chromosomes (telosomes) with a terminal centromere are rare but do exist.
Dal-Hoe Koo +3 more
doaj +1 more source
Genome biology, 2004 The complete sequence of rice centromere 8 reveals a small amount of centromere-specific satellite sequence in blocks interrupted by retrotransposons and other repetitive DNA, in an arrangement that is strikingly similar in overall size and content to other centromeres of multicellular eukaryotes.
James Theuri +2 more
openaire +3 more sources