Results 71 to 80 of about 59,497 (285)

Centromere DNA Dynamics: Latent Centromeres and Neocentromere Formation [PDF]

The American Journal of Human Genetics, 1997
The centromere is a vital chromosomal structure that provides all living cells with the ability to faithfully partition their genetic material during mitotic and meiotic cell divisions. It functions by holding newly replicated sister chromatids together, allowing the attachment of spindle microtubules, and orchestrating the ordered movement of ...
openaire   +2 more sources

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

Arthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean, Carrie Richardson, Anthony Esposito, Katy Bedjeti, George E. Georges   +4 more
wiley   +1 more source

Centromeres [PDF]

Current Biology, 2001
Allshire, Robin, Pidoux, Alison
openaire   +2 more sources

Functional and Comparative Analysis of Centromeres Reveals Clade-Specific Genome Rearrangements in Candida auris and a Chromosome Number Change in Related Species

, 2021
Aswathy Narayanan, Rakesh Netha Vadnala, Promit Ganguly, Pavitra Selvakumar, Shivaprakash M. Rudramurthy, Rajendra Prasad, Arunaloke Chakrabarti, Rahul Siddharthan, Kaustuv Sanyal   +8 more
openalex   +1 more source

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

PBRM1 directs PBAF to pericentromeres and protects centromere integrity

Nature Communications
The specialised structure of the centromere is critical for effective chromosome segregation, but its repetitive nature makes it vulnerable to rearrangements.
Karen A. Lane, Alison Harrod, Lillian Wu, Theodoros I. Roumeliotis, Hugang Feng, Shane Foo, Katheryn A. G. Begg, Federica Schiavoni, Noa Amin, Frank T. Zenke, Alan A. Melcher, Jyoti S. Choudhary, Jessica A. Downs   +12 more
doaj   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

Reconstruction of the kinetochore: a prelude to meiosis

Cell Division, 2007
In eukaryotic organisms, chromosomes are spatially organized within the nucleus. Such nuclear architecture provides a physical framework for the genetic activities of chromosomes, and changes its functional organization as the cell moves through the ...
Haraguchi Tokuko, Asakawa Haruhiko, Hiraoka Yasushi   +2 more
doaj   +1 more source

Zipping up the Synaptonemal Complex: Pathways to Homologous Chromosome Synapsis. [PDF]

Bioessays
The synaptonemal complex (SC) is a conserved protein structure that assembles between homologous chromosomes during meiosis. Here, we review pathways promoting homologous synapsis across model organisms, examining coordination with homolog pairing and recombination, spatiotemporal regulation of SC assembly, and the conserved molecular modules coupling ...
Gold AL, Kim Y.
europepmc   +2 more sources

Centromere-Specifying Nucleosomes Persist in Aging Mouse Oocytes in the Absence of Nascent Assembly

, 2023
Arunika Das, Katelyn G. Boese, Kikuë Tachibana, Sung Hee Baek, Michael A. Lampson, Ben E. Black   +5 more
openalex   +1 more source